Search Results - "Mataija, Diane"

Carbamates with Differential Mechanism of Inhibition Toward Acetylcholinesterase and Butyrylcholinesterase by Darvesh, Sultan, Darvesh, Katherine V, McDonald, Robert S, Mataija, Diane, Walsh, Ryan, Mothana, Sam, Lockridge, Oksana, Martin, Earl

“…Most carbamates are pseudoirreversible inhibitors of cholinesterases. Phenothiazine carbamates exhibit this inhibition of acetylcholinesterase but produce…”
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Selective reversible inhibition of human butyrylcholinesterase by aryl amide derivatives of phenothiazine by Darvesh, Sultan, McDonald, Robert S., Darvesh, Katherine V., Mataija, Diane, Conrad, Sarah, Gomez, Geraldine, Walsh, Ryan, Martin, Earl

“…Synthesized N-(10)-aromatic amides of phenothiazine were specific butyrylcholinesterase inhibitors. Molecular volumes, steric and electronic factors…”
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Differential binding of phenothiazine urea derivatives to wild-type human cholinesterases and butyrylcholinesterase mutants by Darvesh, Sultan, Pottie, Ian R., Darvesh, Katherine V., McDonald, Robert S., Walsh, Ryan, Conrad, Sarah, Penwell, Andrea, Mataija, Diane, Martin, Earl

“…Most phenothiazine urea derivatives are specific butyrylcholinesterase inhibitors. Aminourea derivatives inhibit both acetylcholinesterase and…”
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A qualitative proteome investigation of the sediment portion of human urine: Implications in the biomarker discovery process by Mataija‐Botelho, Diane, Murphy, Patrick, Pinto, Devanand M., MacLellan, Dawn L., Langlois, Chantale, Doucette, Alan A.

“…Inherent to the biomarker discovery process is a comparative analysis of physiological states. It is therefore critical that the proteome detection protocol…”
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Alterations in urinary metabolites due to unilateral ureteral obstruction in a rodent model by MacLellan, Dawn L, Mataija, Diane, Doucette, Alan, Huang, Weei, Langlois, Chantale, Trottier, Greg, Burton, Ian W, Walter, John A, Karakach, Tobias K

“…Urinary tract obstruction (UTO) results in renal compensatory mechanisms and may progress to irrecoverable functional loss and histologic alterations. The…”
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On the active site for hydrolysis of aryl amides and choline esters by human cholinesterases by Darvesh, Sultan, McDonald, Robert S., Darvesh, Katherine V., Mataija, Diane, Mothana, Sam, Cook, Holly, Carneiro, Karina M., Richard, Nicole, Walsh, Ryan, Martin, Earl

“…A series of substituted anilides were examined as substrates for aryl acylamidase activity. The cholinesterase-catalyzed hydrolysis of anilides generally…”
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Structure–activity relationships for inhibition of human cholinesterases by alkyl amide phenothiazine derivatives by Darvesh, Sultan, McDonald, Robert S., Penwell, Andrea, Conrad, Sarah, Darvesh, Katherine V., Mataija, Diane, Gomez, Geraldine, Caines, Angela, Walsh, Ryan, Martin, Earl

“…A number of phenothiazine N-alkyl amide derivatives were synthesized in order to examine the structure–activity relationships for inhibition of human…”
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