Search Results - "Matěj, R"
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Proteinase-activated receptor-2 expression in breast cancer and the role of trypsin on growth and metabolism of breast cancer cell line MDA MB-231
Published in Physiological research (01-01-2007)“…Proteinase-activated receptor-2 (PAR-2) is a ubiquitous surface molecule participating in many biological processes. It belongs to the family of G…”
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Human prion diseases in the Czech Republic
Published in Epidemiologie, mikrobiologie, imunologie (01-09-2015)“…Human prion diseases are a group of very rare diseases with a unique pathogenesis and, due to an inauspicious prognosis and unavailability of therapy, with…”
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PAR2: The Cornerstone of Pancreatic Diseases
Published in Physiological research (31-10-2022)“…It has been 30 years since the first member of the protease-activated receptor (PAR) family was discovered. This was followed by the discovery of three other…”
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PAR2 knock-out C57Bl6 mice as a model for evaluating metastases of cancer cells: pilot in vivo study of the metastatic potential of B16 melanoma in knock-out (PAR2-/-) animals
Published in Folia biologica (2012)“…Proteinase-activated receptor 2 (PAR-2) is a ubiquitous surface molecule. It belongs to the family of G protein-coupled receptors activated by site-specific…”
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PPY-cell hyperplasia accompanying NENs: Immunohistochemical and nuclear medicine analysis
Published in Pathology, research and practice (01-01-2024)“…Pancreatic polypeptide cell hyperplasia (PPY-H) is a multiplication of the neuroendocrine cells producing pancreatic polypeptide (PPY). The development and…”
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Metastatic intracranial spread of adenocarcinoma mimicking Creutzfeldt-Jakob disease in two cases
Published in Revue neurologique (01-10-2021)Get full text
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Relationship between ALS and the degree of cognitive impairment, markers of neurodegeneration and predictors for poor outcome. A prospective study
Published in European journal of neurology (01-01-2010)“…Introduction: Amyotrophic lateral sclerosis (ALS) is a common neurodegenerative disease affecting motor neurons and may be associated with impaired cognition…”
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The frequency of primary cilia, CD8+ tumor infiltrating lymphocytes and PD-1 expression in renal cell carcinoma of clear-cell type
Published in Annals of oncology (01-10-2018)Get full text
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Differential expression and processing of matrix metalloproteinase 19 marks progression of gastrointestinal diseases
Published in Folia biologica (01-01-2014)“…Matrix metalloproteinases (MMPs), responsible for extracellular matrix remodelling and processing of numerous soluble and cell-surface proteins, appear to play…”
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Clinical and molecular practice of European thoracic pathology laboratories during the COVID-19 pandemic. The past and the near future
Published in ESMO open (01-02-2021)“…This study evaluated the consequences in Europe of the COVID-19 outbreak on pathology laboratories orientated toward the diagnosis of thoracic diseases. A…”
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Proteinase-activated receptor-2 expression on cerebral neurones after radiation damage: immunohistochemical observation in Wistar rats
Published in International journal on tissue reactions (2002)“…Radiation damage results in blood-brain barrier damage followed by blood plasma transfer into the neuropil. The transferred liquid contains high amounts of…”
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Amyotrophic lateral sclerosis and Alzheimer's disease - clinical and neuropathological considerations in two cases
Published in European journal of neurology (01-07-2007)“…Amyotrophic lateral sclerosis (ALS) may be accompanied by cognitive impairment; when present, it is mainly in the form of frontotemporal impairment. We report…”
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Anterior opercular syndrome in frontotemporal lobar degeneration with ubiquitin-only immunoreactive neuronal changes
Published in European journal of neurology (01-06-2007)“…This paper presents for the first time an anterior opercular syndrome in association with a gait disorder, dropped head syndrome, dysphagia, and sialorrhea in…”
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Acute pancreatitis: proteinase-activated receptor-2 as Dr. Jekyll and Mr. Hyde
Published in Physiological research (01-01-2006)“…"Proteinase-activated" receptor-2 (PAR-2) is a G protein-coupled transmembrane receptor with seven transmembrane domains activated by trypsin. It has been…”
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Multiple system atrophy and Alzheimer's disease: a case report of a rare association of two neuro-degenerative disorders
Published in Revue neurologique (01-12-2007)“…Multiple system atrophy (MSA) is a neurodegenerative disorder typically characterised by cerebellar dysfunction, parkinsonism, pyramidal signs and dysautonomy…”
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Evaluation of safe resection margins in tumours of parenchymatous organs
Published in Rozhledy v chirurgii (01-02-2014)“…The definition of a safe surgical margin in tumours of parenchymatous organs has been the subject of frequent debates and a number of studies. This topic is…”
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Evaluation of Inflammatory Cells (Tumor Infiltrating Lymphocytes) in Solid Tumors
Published in Klinická onkologie (2017)“…The tumor microenvironment plays an important role in tumorigenesis and the tumor-host relationship. An important part of the tumor microenvironment is…”
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Retrospective sequence analysis of the human PRNP gene from the formaldehyde-fixed paraffin-embedded tissues: report of two cases of Creutzfeldt-Jakob disease
Published in Folia microbiologica (2006)“…The definitive diagnosis of the CJD (Creutzfeldt-Jakob disease; very rare neurodegenerative disorder) can be established only on the basis of post-mortem…”
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Argyrophilic grain disease: case report of the first two cases in the Czech Republic and review of the literature
Published in Ceskoslovenské patologie (01-04-2006)“…Argyrophilic grain disease (AgD) is a relatively newly described neurodegenerative disease with late-onset dementia. Morphologically it is characterized by the…”
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