Search Results - "Masuyer, G."

Structure based drug design of angiotensin-I converting enzyme inhibitors by Anthony, C S, Masuyer, G, Sturrock, E D, Acharya, K R

“…Cardiovascular disease (CVD) is responsible for ∼27% of deaths worldwide, with 80% of these occuring in developing countries. Hypertension is one of the most…”
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Isolation and pharmacological characterization of AdTx1, a natural peptide displaying specific insurmountable antagonism of the α 1A ‐adrenoceptor by Quinton, L, Girard, E, Maiga, A, Rekik, M, Lluel, P, Masuyer, G, Larregola, M, Marquer, C, Ciolek, J, Magnin, T, Wagner, R, Molgó, J, Thai, R, Fruchart‐Gaillard, C, Mourier, G, Chamot‐Rooke, J, Ménez, A, Palea, S, Servent, D, Gilles, N

“…Background and purpose:  Venoms are a rich source of ligands for ion channels, but very little is known about their capacity to modulate G‐protein coupled…”
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Isolation and pharmacological characterization of AdTx1, a natural peptide displaying specific insurmountable antagonism of the α1A‐adrenoceptor by Quinton, L, Girard, E, Maiga, A, Rekik, M, Lluel, P, Masuyer, G, Larregola, M, Marquer, C, Ciolek, J, Magnin, T, Wagner, R, Molgó, J, Thai, R, Fruchart‐Gaillard, C, Mourier, G, Chamot‐Rooke, J, Ménez, A, Palea, S, Servent, D, Gilles, N

“…Background and purpose:  Venoms are a rich source of ligands for ion channels, but very little is known about their capacity to modulate G‐protein coupled…”
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NUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine by Valerie, Nicholas C K, Hagenkort, Anna, Page, Brent D G, Masuyer, Geoffrey, Rehling, Daniel, Carter, Megan, Bevc, Luka, Herr, Patrick, Homan, Evert, Sheppard, Nina G, Stenmark, Pål, Jemth, Ann-Sofie, Helleday, Thomas

“…Thiopurines are a standard treatment for childhood leukemia, but like all chemotherapeutics, their use is limited by inherent or acquired resistance in…”
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Isolation and pharmacological characterization of AdTx1, a natural peptide displaying specific insurmountable antagonism of the alpha1A-adrenoceptor by Quinton, L, Girard, E, Maiga, A, Rekik, M, Lluel, P, Masuyer, G, Larregola, M, Marquer, C, Ciolek, J, Magnin, T, Wagner, R, Molgó, J, Thai, R, Fruchart-Gaillard, C, Mourier, G, Chamot-Rooke, J, Ménez, A, Palea, S, Servent, D, Gilles, N

“…Venoms are a rich source of ligands for ion channels, but very little is known about their capacity to modulate G-protein coupled receptor (GPCR) activity. We…”
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Structural and functional insight into the interaction of Clostridioides difficile toxin B and FZD7 by Kinsolving, Julia, Bous, Julien, Kozielewicz, Pawel, Košenina, Sara, Shekhani, Rawan, Grätz, Lukas, Masuyer, Geoffrey, Wang, Yuankai, Stenmark, Pål, Dong, Min, Schulte, Gunnar

“…The G protein-coupled receptors of the Frizzled (FZD) family, in particular FZD1,2,7, are receptors that are exploited by Clostridioides difficile toxin B…”
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Mechanism of Peptide Binding and Cleavage by the Human Mitochondrial Peptidase Neurolysin by Teixeira, Pedro F., Masuyer, Geoffrey, Pinho, Catarina M., Branca, Rui M.M., Kmiec, Beata, Wallin, Cecilia, Wärmländer, Sebastian K.T.S., Berntsson, Ronnie P.-A., Ankarcrona, Maria, Gräslund, Astrid, Lehtiö, Janne, Stenmark, Pål, Glaser, Elzbieta

“…Proteolysis plays an important role in mitochondrial biogenesis, from the processing of newly imported precursor proteins to the degradation of mitochondrial…”
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Optimization of N‐Piperidinyl‐Benzimidazolone Derivatives as Potent and Selective Inhibitors of 8‐Oxo‐Guanine DNA Glycosylase 1 by Wallner, Olov, Cázares‐Körner, Armando, Scaletti, Emma Rose, Masuyer, Geoffrey, Bekkhus, Tove, Visnes, Torkild, Mamonov, Kirill, Ortis, Florian, Lundbäck, Thomas, Volkova, Maria, Koolmeister, Tobias, Wiita, Elisée, Loseva, Olga, Pandey, Monica, Homan, Evert, Benítez‐Buelga, Carlos, Davies, Jonathan, Scobie, Martin, Warpman Berglund, Ulrika, Kalderén, Christina, Stenmark, Pål, Helleday, Thomas, Michel, Maurice

“…8‐oxo Guanine DNA Glycosylase 1 is the initiating enzyme within base excision repair and removes oxidized guanines from damaged DNA. Since unrepaired 8‐oxoG…”
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Isolation and pharmacological characterization of AdTx1, a natural peptide displaying specific insurmountable antagonism of the alpha(1A)-adrenoceptor by Quinton, L., Girard, Emmanuelle, Maiga, A., Rekik, M., Lluel, P., Masuyer, G., Larregola, M., Marquer, C., Ciolek, J., Magnin, T., Wagner, R., Molgó, Jordi, Thai, Robert, Fruchart-Gaillard, C., Mourier, Gilles, Chamot-Rooke, J., Ménez, André, Palea, S., Servent, Denis, Gilles, Nicolas

“…Background and purpose: Venoms are a rich source of ligands for ion channels, but very little is known about their capacity to modulate G-protein coupled…”
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Crystal structure of a catalytically active, non-toxic endopeptidase derivative of Clostridium botulinum toxin A by Masuyer, Geoffrey, Thiyagarajan, Nethaji, James, Peter L., Marks, Philip M.H., Chaddock, John A., Acharya, K. Ravi

“…Botulinum neurotoxins (BoNTs) modulate cholinergic nerve terminals to result in neurotransmitter blockade. BoNTs consists of catalytic (LC), translocation (Hn)…”
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Isolation and pharmacological characterization of AdTx1, a natural peptide displaying specific insurmountable antagonism of the [alpha]1A-adrenoceptor by Quinton, L, Girard, E, Maiga, A, Rekik, M, Lluel, P, Masuyer, G, Larregola, M, Marquer, C, Ciolek, J, Magnin, T, Wagner, R, Molgo, J, Thai, R, Fruchart-Gaillard, C, Mourier, G, Chamot-Rooke, J, Menez, A, Palea, S, Servent, D, Gilles, N

“…Background and purpose: Venoms are a rich source of ligands for ion channels, but very little is known about their capacity to modulate G-protein coupled…”
Get full text