Search Results - "Masumoto, Shuji"

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  1. 1

    Catalytic Enantioselective Strecker Reaction of Ketoimines by Masumoto, Shuji, Usuda, Hiroyuki, Suzuki, Masato, Kanai, Motomu, Shibasaki, Masakatsu

    Published in Journal of the American Chemical Society (14-05-2003)
    “…A new method for the catalytic enantioselective Strecker reaction (cyanation) of N-diphenylphosphinoyl ketoimines is described. The asymmetric catalyst is a…”
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    Design, synthesis and structure–activity relationships of novel benzoxazolone derivatives as 18kDa translocator protein (TSPO) ligands by Fukaya, Takayuki, Kodo, Toru, Ishiyama, Takeo, Kakuyama, Hiroyoshi, Nishikawa, Hiroyuki, Baba, Satoko, Masumoto, Shuji

    Published in Bioorganic & medicinal chemistry (01-09-2012)
    “…Benzoxazolone derivatives were designed and synthesized as novel TSPO ligands. In view of initial SAR study, we selected compound 14 as lead compound. Further…”
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    Catalytic asymmetric synthesis of ( S)-oxybutynin and a versatile intermediate for antimuscarinic agents by Masumoto, Shuji, Suzuki, Masato, Kanai, Motomu, Shibasaki, Masakatsu

    Published in Tetrahedron (08-11-2004)
    “…A practical synthesis of ( S)-oxybutynin, a muscarinic receptor antagonist, using catalytic enantioselective cyanosilylation of cyclohexyl phenyl ketone ( 9a )…”
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  5. 5

    Studies toward practical synthesis of (20 S)-camptothecin family through catalytic enantioselective cyanosilylation of ketones: improved catalyst efficiency by ligand-tuning by Yabu, Kazuo, Masumoto, Shuji, Kanai, Motomu, Curran, Dennis P., Shibasaki, Masakatsu

    Published in Tetrahedron letters (15-04-2002)
    “…Enantioselective catalyst efficiency for the synthesis of the camptothecin family was improved through ligand-tuning. Key intermediates of two convergent…”
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  6. 6

    Rat leucine-rich protein binds and activates the promoter of the beta isoform of Ca2+/calmodulin-dependent protein kinase II gene by Ochiai, Nagahiro, Masumoto, Shuji, Sakagami, Hiroyuki, Yoshimura, Yoshiyuki, Yamauchi, Takashi

    Published in Neuroscience research (01-05-2007)
    “…We previously found the neuronal cell-type specific promoter and binding partner of the beta isoform of Ca(2+)/calmodulin-dependent protein kinase II (beta CaM…”
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  7. 7

    Rat leucine-rich protein binds and activates the promoter of the β isoform of Ca 2+/calmodulin-dependent protein kinase II gene by Ochiai, Nagahiro, Masumoto, Shuji, Sakagami, Hiroyuki, Yoshimura, Yoshiyuki, Yamauchi, Takashi

    Published in Neuroscience research (01-05-2007)
    “…We previously found the neuronal cell-type specific promoter and binding partner of the β isoform of Ca 2+/calmodulin-dependent protein kinase II (β CaM kinase…”
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    Identification of a Novel Benzoxazolone Derivative as a Selective, Orally Active 18 kDa Translocator Protein (TSPO) Ligand by Fukaya, Takayuki, Ishiyama, Takeo, Baba, Satoko, Masumoto, Shuji

    Published in Journal of medicinal chemistry (24-10-2013)
    “…Optimization of the pharmacokinetic properties for a series of benzoxazolone derivatives led to the identification of 9b, which showed anxiolytic effect in a…”
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  10. 10

    Synthesis of Unsymmetrically Substituted Antimony(V) Tetraphenylporphyrins by Satoh, Wataru, Masumoto, Shuji, Shimizu, Masakazu, Yamamoto, Yohsuke, Akiba, Kin-ya

    Published in Bulletin of the Chemical Society of Japan (01-03-1999)
    “…The following nine unsymmetrically axially substituted antimony(V) tetraphenylporphyrins with an antimony–carbon bond or an antimony–fluorine bond were…”
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    Design, synthesis and structure―activity relationships of novel benzoxazolone derivatives as 18 kDa translocator protein (TSPO) ligands by FUKAYA, Takayuki, KODO, Toru, ISHIYAMA, Takeo, KAKUYAMA, Hiroyoshi, NISHIKAWA, Hiroyuki, BABA, Satoko, MASUMOTO, Shuji

    Published in Bioorganic & medicinal chemistry (15-09-2012)
    “…Selective 18 kDa translocator protein (TSPO) ligands are expected to be therapeutic agents with a wide spectrum of action on psychiatric disorders and fewer…”
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  12. 12

    Design, synthesis and structure-activity relationship of novel tricyclic benzimidazolone derivatives as potent 18 kDa translocator protein (TSPO) ligands by Fukaya, Takayuki, Kodo, Toru, Ishiyama, Takeo, Nishikawa, Hiroyuki, Baba, Satoko, Masumoto, Shuji

    Published in Bioorganic & medicinal chemistry (01-03-2013)
    “…The 18 kDa translocator protein (TSPO) was identified as a discrete receptor for diazepam (1). Since TSPO in the central nervous system (CNS) is believed to…”
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    Design, synthesis and structure–activity relationship of novel tricyclic benzimidazolone derivatives as potent 18kDa translocator protein (TSPO) ligands by Fukaya, Takayuki, Kodo, Toru, Ishiyama, Takeo, Nishikawa, Hiroyuki, Baba, Satoko, Masumoto, Shuji

    Published in Bioorganic & medicinal chemistry (01-03-2013)
    “…We obtained dihydroimidazoquinolinone derivatives with potent affinity for TSPO (subnanomolar Ki values), by conversion of the benzoxazolone skeleton to a…”
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  15. 15

    A practical synthesis of ( S)-oxybutynin by Masumoto, Shuji, Suzuki, Masato, Kanai, Motomu, Shibasaki, Masakatsu

    Published in Tetrahedron letters (25-11-2002)
    “…( S)-Oxybutynin, an important drug acting as muscarinic receptor antagonist, was practically synthesized using catalytic enantioselective cyanosilylation of…”
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    Practical synthesis of chiral ligands for catalytic enantioselective cyanosilylation of ketones by Masumoto, Shuji, Yabu, Kazuo, Kanai, Motomu, Shibasaki, Masakatsu

    Published in Tetrahedron letters (15-04-2002)
    “…A practical and more environmentally benign synthetic route of chiral ligands that are useful for catalytic enantioselective cyanosilylation of ketones is…”
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  18. 18

    Tricyclic Indole-2-carboxylic Acids:  Highly in Vivo Active and Selective Antagonists for the Glycine Binding Site of the NMDA Receptor by Katayama, Seiji, Ae, Nobuyuki, Kodo, Toru, Masumoto, Shuji, Hourai, Shinji, Tamamura, Chika, Tanaka, Hiroyasu, Nagata, Ryu

    Published in Journal of medicinal chemistry (27-02-2003)
    “…A series of tricyclic indole-2-carboxylic acid derivatives were synthesized and evaluated by the radioligand binding assay and the anticonvulsant effects in…”
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  19. 19

    Synthesis and Electrochemistry of Tetraphenylporphyrins Containing an Antimony−Carbon σ-Bond by Kadish, Karl M, Autret, Marie, Ou, Zhongping, Akiba, Kin-ya, Masumoto, Shuji, Wada, Ryosuke, Yamamoto, Yohsuke

    Published in Inorganic chemistry (11-09-1996)
    “…The following five antimony(V) tetraphenylporphyrins with σ-bonded antimony−carbon bonds were synthesized:  [(TPP)Sb(CH3)2]+PF6 -, [(TPP)Sb(OCH3)(OH)]+PF6 -,…”
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