Search Results - "Masumoto, Mari"
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AS3288802, a highly selective antibody to active plasminogen activator inhibitor-1 (PAI-1), exhibits long efficacy duration in cynomolgus monkeys
Published in Biologicals (01-09-2020)“…Antibodies have strong affinity to their target molecules, a characteristic that is utilized in antibody drugs. For antibody drugs, target molecule specificity…”
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Discovery of a Novel Nicotinamide Phosphoribosyl Transferase (NAMPT) Inhibitor via in Silico Screening
Published in Biological & pharmaceutical bulletin (01-01-2014)“…Nicotinamide phosphoribosyl transferase (NAMPT) is a key enzyme in the salvage pathway of mammalian nicotinamide adenine dinucleotide (NAD) biosynthesis,…”
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Dexamethasone Inhibits Collagen Degradation Induced by the Combination of Interleukin-1 and Plasminogen in Cartilage Explant Culture
Published in Biological & pharmaceutical bulletin (01-07-1999)“…Glucocorticoids ameliorate erosion in animal osteoarthritis (OA) models and suppress synthesis of matrix matalloproteinases (MMP). However, in in vitro…”
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Involvement of MMP-1 and MMP-3 in collagen degradation induced by IL-1 in rabbit cartilage explant culture
Published in Life sciences (1973) (24-04-1998)“…To determine whether matrix metalloproteinase-1 (MMP-1) or MMP-3 is involved in cartilage collagen degradation, polyclonal antibodies were separately raised…”
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Collagen Degradation Induced by the Combination of IL-1α and Plasminogen in Rabbit Articular Cartilage Explant Culture
Published in Journal of biochemistry (Tokyo) (01-07-1997)“…To investigate the effect of plasminogen on cartilage catabolism, we assessed collagen degradation in rabbit articular cartilage explants treated with or…”
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Collagen degradation induced by the combination of IL-1alpha and plasminogen in rabbit articular cartilage explant culture
Published in Journal of biochemistry (Tokyo) (01-07-1997)“…To investigate the effect of plasminogen on cartilage catabolism, we assessed collagen degradation in rabbit articular cartilage explants treated with or…”
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