Search Results - "Masui, Colin"

High-throughput screening and scale-up of cocrystals using resonant acoustic mixing by Nagapudi, Karthik, Umanzor, Evelyn Yanez, Masui, Colin

“…[Display omitted] This paper explores the effectiveness of resonant acoustic mixing RAM for screening and scale up of cocrystals. 16 cocrystal systems were…”
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Synthesis of Selective Estrogen Receptor Degrader GDC-0810 via Stereocontrolled Assembly of a Tetrasubstituted All-Carbon Olefin by Savage, Scott, McClory, Andrew, Zhang, Haiming, Cravillion, Theresa, Lim, Ngiap-Kie, Masui, Colin, Robinson, Sarah J, Han, Chong, Ochs, Christoph, Rege, Pankaj D, Gosselin, Francis

“…We report an efficient synthesis of GDC-0810 on the basis of a sequence involving a highly stereoselective lithium tert-butoxide-mediated…”
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Achiral–Chiral Two-Dimensional Liquid Chromatography Platform to Support Automated High-Throughput Experimentation in the Field of Drug Development by Goyon, Alexandre, Masui, Colin, Sirois, Lauren E, Han, Chong, Yehl, Peter, Gosselin, Francis, Zhang, Kelly

“…Automated high-throughput experimentation (HTE) is a powerful tool for scientists to explore and optimize chemical transformations by simultaneously screening…”
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GNE-781, A Highly Advanced Potent and Selective Bromodomain Inhibitor of Cyclic Adenosine Monophosphate Response Element Binding Protein, Binding Protein (CBP) by Romero, F. Anthony, Murray, Jeremy, Lai, Kwong Wah, Tsui, Vickie, Albrecht, Brian K, An, Le, Beresini, Maureen H, de Leon Boenig, Gladys, Bronner, Sarah M, Chan, Emily W, Chen, Kevin X, Chen, Zhongguo, Choo, Edna F, Clagg, Kyle, Clark, Kevin, Crawford, Terry D, Cyr, Patrick, de Almeida Nagata, Denise, Gascoigne, Karen E, Grogan, Jane L, Hatzivassiliou, Georgia, Huang, Wei, Hunsaker, Thomas L, Kaufman, Susan, Koenig, Stefan G, Li, Ruina, Li, Yingjie, Liang, Xiaorong, Liao, Jiangpeng, Liu, Wenfeng, Ly, Justin, Maher, Jonathan, Masui, Colin, Merchant, Mark, Ran, Yingqing, Taylor, Alexander M, Wai, John, Wang, Fei, Wei, Xiaocang, Yu, Dong, Zhu, Bing-Yan, Zhu, Xiaoyu, Magnuson, Steven

“…Inhibition of the bromodomain of the transcriptional regulator CBP/P300 is an especially interesting new therapeutic approach in oncology. We recently…”
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Imido and amido complexes of hydrotris(pyrazolyl)borate-rhenium by Masui, Colin S., Mayer, James M.

“…Rhenium(V) para-tolylimido complexes TpRe(NTol)X 2 (X = Cl ( 2a); I ( 2b)) are formed on refluxing the oxo derivatives TpRe(O)X 2 (X = Cl ( 1a); I ( 1b)) with…”
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