Search Results - "Mastracci, L"

Krt19+/Lgr5− Cells Are Radioresistant Cancer-Initiating Stem Cells in the Colon and Intestine by Asfaha, Samuel, Hayakawa, Yoku, Muley, Ashlesha, Stokes, Sarah, Graham, Trevor A., Ericksen, Russell E., Westphalen, Christoph B., von Burstin, Johannes, Mastracci, Teresa L., Worthley, Daniel L., Guha, Chandhan, Quante, Michael, Rustgi, Anil K., Wang, Timothy C.

“…Epithelium of the colon and intestine are renewed every 3 days. In the intestine there are at least two principal stem cell pools. The first contains rapid…”
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Exocrine-Endocrine Crosstalk: The Influence of Pancreatic Cellular Communications on Organ Growth, Function and Disease by Overton, Danielle L, Mastracci, Teresa L

“…Diabetes mellitus, a disease that affects nearly 536.6 million people worldwide, is characterized by the death or dysfunction of insulin-producing beta cells…”
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Regulation of Neurod1 contributes to the lineage potential of Neurogenin3+ endocrine precursor cells in the pancreas by Mastracci, Teresa L, Anderson, Keith R, Papizan, James B, Sussel, Lori

“…During pancreatic development, transcription factor cascades gradually commit precursor populations to the different endocrine cell fate pathways. Although…”
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Deoxyhypusine synthase deficiency syndrome zebrafish model: aberrant morphology, epileptiform activity, and reduced arborization of inhibitory interneurons by Shojaeinia, Elham, Mastracci, Teresa L, Soliman, Remon, Devinsky, Orrin, Esguerra, Camila V, Crawford, Alexander D

“…DHPS deficiency syndrome is an ultra-rare neurodevelopmental disorder (NDD) which results from biallelic mutations in the gene encoding the enzyme…”
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Hypusinated eIF5A is expressed in the pancreas and spleen of individuals with type 1 and type 2 diabetes by Mastracci, Teresa L, Colvin, Stephanie C, Padgett, Leah R, Mirmira, Raghavendra G

“…The gene encoding eukaryotic initiation factor 5A (EIF5A) is found in diabetes-susceptibility loci in mouse and human. eIF5A is the only protein known to…”
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Evaluating mismatch repair deficiency in colorectal cancer biopsy specimens by Grillo, F., Paudice, M., Gambella, A., Bozzano, S., Sciallero, S., Puccini, A., Lastraioli, S., Dono, M., Parente, P., Vanoli, A., Angerilli, V., Fassan, M., Mastracci, L.

“…Mismatch repair (MMR) testing on all new cases of colorectal cancer (CRC) has customarily been preferably performed on surgical specimens, as more tissue is…”
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Combining germline, tissue and liquid biopsy analysis by comprehensive genomic profiling to improve the yield of actionable variants in a real-world cancer cohort by Vanni, I, Pastorino, L, Andreotti, V, Comandini, D, Fornarini, G, Grassi, M, Puccini, A, Tanda, E T, Pastorino, A, Martelli, V, Mastracci, L, Grillo, F, Cabiddu, F, Guadagno, A, Coco, S, Allavena, E, Barbero, F, Bruno, W, Dalmasso, B, Bellomo, S E, Marchiò, C, Spagnolo, F, Sciallero, S, Berrino, E, Ghiorzo, P

“…Comprehensive next-generation sequencing is widely used for precision oncology and precision prevention approaches. We aimed to determine the yield of…”
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Polyamine biosynthesis is critical for growth and differentiation of the pancreas by Mastracci, Teresa L., Robertson, Morgan A., Mirmira, Raghavendra G., Anderson, Ryan M.

“…The pancreas, in most studied vertebrates, is a compound organ with both exocrine and endocrine functions. The exocrine compartment makes and secretes…”
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Quality control in diagnostic immunohistochemistry: integrated on-slide positive controls by Bragoni, A., Gambella, A., Pigozzi, S., Grigolini, M., Fiocca, R., Mastracci, L., Grillo, F.

“…Standardization in immunohistochemistry is a priority in modern pathology and requires strict quality control. Cost containment has also become fundamental and…”
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Tumor regression grading after neoadjuvant treatment of esophageal and gastroesophageal junction adenocarcinoma: results of an international Delphi consensus survey by Saliba, G., Detlefsen, S., Carneiro, F., Conner, J., Dorer, R., Fléjou, J.F., Hahn, H., Kamaradova, K., Mastracci, L., Meijer, S.L., Sabo, E., Sheahan, K., Riddell, R., Wang, N., Yantiss, R.K., Lundell, L., Low, D., Vieth, M., Klevebro, F.

“…Complete histopathologic tumor regression after neoadjuvant treatment is a well-known prognostic factor for survival among patients with adenocarcinomas of the…”
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Dissociation of the Glucose and Lipid Regulatory Functions of FoxO1 by Targeted Knockin of Acetylation-Defective Alleles in Mice by Banks, Alexander S., Kim-Muller, Ja Young, Mastracci, Teresa L., Kofler, Natalie M., Qiang, Li, Haeusler, Rebecca A., Jurczak, Michael J., Laznik, Dina, Heinrich, Garrett, Samuel, Varman T., Shulman, Gerald I., Papaioannou, Virginia E., Accili, Domenico

“…FoxO1 integrates multiple metabolic pathways. Nutrient levels modulate FoxO1 acetylation, but the functional consequences of this posttranslational…”
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GABAergic Differentiation Induced by Mash1 Is Compromised by the bHLH Proteins Neurogenin2, NeuroD1, and NeuroD2 by Roybon, Laurent, Mastracci, Teresa L., Ribeiro, Diogo, Sussel, Lori, Brundin, Patrik, Li, Jia-Yi

“…During forebrain development, Mash1 directs γ-aminobutyric acid (GABA)ergic neuron differentiation ventrally in the ganglionic eminences. Repression of Mash1…”
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The dynamics of the oesophageal squamous epithelium ‘normalisation’ process in patients with gastro‐oesophageal reflux disease treated with long‐term acid suppression or anti‐reflux surgery by Mastracci, L., Fiocca, R., Engström, C., Attwood, S., Ell, C., Galmiche, J. P., Hatlebakk, J. G., Långström, G., Eklund, S., Lind, T., Lundell, L.

“…Summary Background Proton pump inhibitors and laparoscopic anti‐reflux surgery (LARS) offer long‐term symptom control to patients with gastro‐oesophageal…”
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Deoxyhypusine synthase mutations alter the post-translational modification of eukaryotic initiation factor 5A resulting in impaired human and mouse neural homeostasis by Padgett, Leah R., Shinkle, Mollie R., Rosario, Spencer, Stewart, Tracy Murray, Foley, Jackson R., Casero, Robert A., Park, Myung Hee, Chung, Wendy K., Mastracci, Teresa L.

“…DHPS deficiency is a rare genetic disease caused by biallelic hypomorphic variants in the Deoxyhypusine synthase (DHPS) gene. The DHPS enzyme functions in mRNA…”
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Nkx2.2 and Arx genetically interact to regulate pancreatic endocrine cell development and endocrine hormone expression by Mastracci, Teresa L., Wilcox, Crystal L., Arnes, Luis, Panea, Casandra, Golden, Jeffrey A., May, Catherine Lee, Sussel, Lori

“…Nkx2.2 and Arx are essential pancreatic transcription factors. Nkx2.2 is necessary for the appropriate specification of the islet alpha, beta, PP and epsilon…”
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The novel enterochromaffin marker Lmx1a regulates serotonin biosynthesis in enteroendocrine cell lineages downstream of Nkx2.2 by Gross, Stefanie, Garofalo, Diana C, Balderes, Dina A, Mastracci, Teresa L, Dias, José M, Perlmann, Thomas, Ericson, Johan, Sussel, Lori

“…Intestinal hormone-producing cells represent the largest endocrine system in the body, but remarkably little is known about enteroendocrine cell type…”
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Molecular characterization of an Italian series of sporadic GISTs by Origone, P., Gargiulo, S., Mastracci, L., Ballestrero, A., Battistuzzi, L., Casella, C., Comandini, D., Cusano, R., Dei Tos, A. P., Fiocca, R., Garuti, A., Ghiorzo, P., Martinuzzi, C., Toffolatti, L., Bianchi Scarrà, G.

“…Purpose Gastrointestinal stromal tumors (GISTs) are mesenchymal tumors of the gastrointestinal tract. Most (80 %) contain activating mutations in the KIT…”
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Gastric exocrine and endocrine cell morphology under prolonged acid inhibition therapy: results of a 5-year follow-up in the LOTUS trial by Fiocca, R., Mastracci, L., Attwood, S. E., Ell, C., Galmiche, J.-P., Hatlebakk, J., Bärthel, A., Långström, G., Lind, T., Lundell, L.

“…Summary Background Sustained acid inhibition with PPI stimulates gastrin secretion, exerting a proliferative drive on enterochromaffin‐like cells (ECL cells)…”
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The Origin, Development and Molecular Diversity of Rodent Olfactory Bulb Glutamatergic Neurons Distinguished by Expression of Transcription Factor NeuroD1 by Roybon, Laurent, Mastracci, Teresa L, Li, Joyce, Stott, Simon R W, Leiter, Andrew B, Sussel, Lori, Brundin, Patrik, Li, Jia-Yi

“…Production of olfactory bulb neurons occurs continuously in the rodent brain. Little is known, however, about cellular diversity in the glutamatergic neuron…”
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Editorial: the diminishing returns of normalisation of the oesophageal mucosa―Authors' reply by Mastracci, L., Fiocca, R., Engstrom, C., Attwood, S., Ell, C., Galmiche, J. P., Hatlebakk, J. G., Långström, G., Eklund, S., Lind, T., Lundell, L.

“…Linked ContentThis article is linked to Mastracci et al and Genta papers. To view these articles visit https://doi.org/10.1111/apt.14038 and…”
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