Search Results - "Masterson, Victoria M"

Evaluating particle hardness of pharmaceutical solids using AFM nanoindentation by Masterson, Victoria M., Cao, Xiaoping

“…Understanding mechanical properties of pharmaceutical solids at the submicron scale can be very important to pharmaceutical research & development. In this…”
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C-Aryl glycoside inhibitors of SGLT2: Exploration of sugar modifications including C-5 spirocyclization by Robinson, Ralph P., Mascitti, Vincent, Boustany-Kari, Carine M., Carr, Christopher L., Foley, Patrick M., Kimoto, Emi, Leininger, Michael T., Lowe, Andre, Klenotic, Michelle K., MacDonald, James I., Maguire, Robert J., Masterson, Victoria M., Maurer, Tristan S., Miao, Zhuang, Patel, Jigna D., Préville, Cathy, Reese, Matthew R., She, Li, Steppan, Claire M., Thuma, Benjamin A., Zhu, Tong

“…Modifications to the sugar portion of C-aryl glycoside sodium glucose transporter 2 (SGLT2) inhibitors were explored, including systematic deletion and…”
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Estimating the refractive index of pharmaceutical solids using predictive methods by Cao, Xiaoping, Hancock, Bruno C., Leyva, Norma, Becker, Jennifer, Yu, Weili, Masterson, Victoria M.

“…Refractive index is a basic physical property of pharmaceutical solids. In this paper, the refractive index values of 424 pharmaceutical solids from the…”
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Discovery of a Clinical Candidate from the Structurally Unique Dioxa-bicyclo[3.2.1]octane Class of Sodium-Dependent Glucose Cotransporter 2 Inhibitors by Mascitti, Vincent, Maurer, Tristan S, Robinson, Ralph P, Bian, Jianwei, Boustany-Kari, Carine M, Brandt, Thomas, Collman, Benjamin M, Kalgutkar, Amit S, Klenotic, Michelle K, Leininger, Michael T, Lowe, André, Maguire, Robert J, Masterson, Victoria M, Miao, Zhuang, Mukaiyama, Emi, Patel, Jigna D, Pettersen, John C, Préville, Cathy, Samas, Brian, She, Li, Sobol, Zhanna, Steppan, Claire M, Stevens, Benjamin D, Thuma, Benjamin A, Tugnait, Meera, Zeng, Dongxiang, Zhu, Tong

“…Compound 4 (PF-04971729) belongs to a new class of potent and selective sodium-dependent glucose cotransporter 2 inhibitors incorporating a unique…”
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Correlating particle hardness with powder compaction performance by Cao, Xiaoping, Morganti, Mikayla, Hancock, Bruno C, Masterson, Victoria M

“…Assessing particle mechanical properties of pharmaceutical materials quickly and with little material can be very important to early stages of pharmaceutical…”
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Design and Synthesis of Diazatricyclodecane Agonists of the G‑Protein-Coupled Receptor 119 by Darout, Etzer, Robinson, Ralph P, McClure, Kim F, Corbett, Matthew, Li, Bryan, Shavnya, Andrei, Andrews, Melissa P, Jones, Christopher S, Li, Qifang, Minich, Martha L, Mascitti, Vincent, Guimarães, Cristiano R. W, Munchhof, Michael J, Bahnck, Kevin B, Cai, Cuiman, Price, David A, Liras, Spiros, Bonin, Paul D, Cornelius, Peter, Wang, Ruduan, Bagdasarian, Victoria, Sobota, Colleen P, Hornby, Sam, Masterson, Victoria M, Joseph, Reena M, Kalgutkar, Amit S, Chen, Yue

“…A series of GPR119 agonists based on a 2,6-diazatricyclo[3.3.1.1∼3,7∼]decane ring system is described. Also provided is a detailed account of the development…”
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