Search Results - "Masterson, R."
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The Business Case for Women Leaders: Meta-Analysis, Research Critique, and Path Forward
Published in Journal of management (01-07-2018)“…Since the 1990s, a growing body of research has sought to quantify the relationship between women’s representation in leadership positions and organizational…”
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Dynamics connect substrate recognition to catalysis in protein kinase A
Published in Nature chemical biology (01-11-2010)“…Structural analysis of protein kinase A had previously focused on static pictures with bound inhibitors. The first analyses of the protein with a substrate…”
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Dynamically committed, uncommitted, and quenched states encoded in protein kinase A revealed by NMR spectroscopy
Published in Proceedings of the National Academy of Sciences - PNAS (26-04-2011)“…Protein kinase A (PKA) is a ubiquitous phosphoryl transferase that mediates hundreds of cell signaling events. During turnover, its catalytic subunit (PKA-C)…”
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ABO Incompatible Renal Transplantation Without Antibody Removal Using Conventional Immunosuppression Alone
Published in American journal of transplantation (01-12-2014)“…ABO incompatible living donor renal transplantation (ABOi) can achieve outcomes comparable to ABO compatible transplantation (ABOc). However, with the…”
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Allosteric cooperativity in protein kinase A
Published in Proceedings of the National Academy of Sciences - PNAS (15-01-2008)“…Allosteric signaling in proteins requires long-range communication mediated by highly conserved residues, often triggered by ligand binding. In this article,…”
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Dysfunctional conformational dynamics of protein kinase A induced by a lethal mutant of phospholamban hinder phosphorylation
Published in Proceedings of the National Academy of Sciences - PNAS (24-03-2015)“…Significance In the heart, phospholamban regulates Ca ²⁺-ATPase function, controlling cardiac output. A single deletion (R14del) in the phospholamban…”
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Regolith X-Ray Imaging Spectrometer (REXIS) Aboard the OSIRIS-REx Asteroid Sample Return Mission
Published in Space science reviews (01-02-2018)“…The Regolith X-ray Imaging Spectrometer (REXIS) is the student collaboration experiment proposed and built by an MIT-Harvard team, launched aboard NASA’s…”
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Synchronous Opening and Closing Motions Are Essential for cAMP-Dependent Protein Kinase A Signaling
Published in Structure (London) (02-12-2014)“…Conformational fluctuations play a central role in enzymatic catalysis. However, it is not clear how the rates and the coordination of the motions affect the…”
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Structure and dynamics of a primordial catalytic fold generated by in vitro evolution
Published in Nature chemical biology (01-02-2013)“…Structural characterization of an artificial zinc-dependent enzyme created by in vitro evolution yields a new, flexible fold that challenges straightforward…”
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Lethal Arg9Cys phospholamban mutation hinders Ca²⁺-ATPase regulation and phosphorylation by protein kinase A
Published in Proceedings of the National Academy of Sciences - PNAS (15-02-2011)“…The regulatory interaction of phospholamban (PLN) with Ca²⁺-ATPase controls the uptake of calcium into the sarcoplasmic reticulum, modulating heart muscle…”
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Allostery and Binding Cooperativity of the Catalytic Subunit of Protein Kinase A by NMR Spectroscopy and Molecular Dynamics Simulations
Published in Advances in Protein Chemistry and Structural Biology (2012)“…The catalytic subunit of cAMP-dependent protein kinase A (PKA-C) is an exquisite example of a single molecule allosteric enzyme, where classical and modern…”
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A Myristoyl/Phosphoserine Switch Controls cAMP-Dependent Protein Kinase Association to Membranes
Published in Journal of molecular biology (26-08-2011)“…The cAMP-dependent protein kinase [protein kinase A (PKA)] mediates a myriad of cellular signaling events, and its activity is tightly regulated in both space…”
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DEVELOPMENT AND VALIDATION OF REACTION WHEEL DISTURBANCE MODELS: EMPIRICAL MODEL
Published in Journal of sound and vibration (17-01-2002)“…Accurate disturbance models are necessary to predict the effects of vibrations on the performance of precision space-based telescopes, such as the Space…”
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Clinically relevant doses of lidocaine and bupivacaine do not impair cutaneous wound healing in mice
Published in British journal of anaesthesia : BJA (01-06-2010)“…Background Lidocaine and bupivacaine are commonly infiltrated into surgical cutaneous wounds to provide local anaesthesia after surgical procedures. However,…”
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FLAMEnGO: A fuzzy logic approach for methyl group assignment using NOESY and paramagnetic relaxation enhancement data
Published in Journal of magnetic resonance (1997) (01-01-2012)“…[Display omitted] ► A new assignment procedure (FLAMEnGO) for methyl groups based on NOEs. ► FLAMEnGO uses fuzzy logic, Monte Carlo sampling, and…”
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X-chromosome inactivation in monkey embryos and pluripotent stem cells
Published in Developmental biology (15-11-2012)“…Inactivation of one X chromosome in female mammals (XX) compensates for the reduced dosage of X-linked gene expression in males (XY). However, the inner cell…”
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Prediction of pre‐eclampsia in early pregnancy by estimating the spot urinary albumin: creatinine ratio using high‐performance liquid chromatography
Published in BJOG : an international journal of obstetrics and gynaecology (01-08-2011)“…Please cite this paper as: Baweja S, Kent A, Masterson R, Roberts S, McMahon L. Prediction of pre‐eclampsia in early pregnancy by estimating the spot urinary…”
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Self‐ambivalence: Naming a contemporary work–family problem that has no name
Published in Journal of organizational behavior (01-02-2024)“…Summary As workers and family members, individuals ought to celebrate seemingly positive events (e.g., a promotion and the purchase of a home). Yet, the…”
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Case Report: Thrombotic Microangiopathy Post-intravenous Immunoglobulin in the Context of BK Nephropathy and Renal Transplantation
Published in Transplantation proceedings (2014)“…Abstract Intravenous immunoglobulin (IVIg) is a blood product with immunomodulating properties that have been widely applied in the management of renal…”
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