Search Results - "Master, Stephen R"

Supervised Multi-View Canonical Correlation Analysis (sMVCCA): Integrating Histologic and Proteomic Features for Predicting Recurrent Prostate Cancer by Lee, George, Singanamalli, Asha, Haibo Wang, Feldman, Michael D., Master, Stephen R., Shih, Natalie N. C., Spangler, Elaine, Rebbeck, Timothy, Tomaszewski, John E., Madabhushi, Anant

“…In this work, we present a new methodology to facilitate prediction of recurrent prostate cancer (CaP) following radical prostatectomy (RP) via the integration…”
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Urine Neutrophil Gelatinase-Associated Lipocalin and Risk of Cardiovascular Disease and Death in CKD: Results From the Chronic Renal Insufficiency Cohort (CRIC) Study by Liu, Kathleen D., MD, PhD, Yang, Wei, PhD, Go, Alan S., MD, Anderson, Amanda H., PhD, Feldman, Harold I., MD, MSCE, Fischer, Michael J., MD, MSPH, He, Jiang, MD, PhD, Kallem, Radhakrishna R., MD, MPH, Kusek, John W., PhD, Master, Stephen R., MD, PhD, Miller, Edgar R., MD, Rosas, Sylvia E., MD, Steigerwalt, Susan, MD, Tao, Kaixiang, PhD, Weir, Matthew R., MD, Hsu, Chi-yuan, MD, MSc

“…Background Chronic kidney disease is common and is associated with increased cardiovascular disease risk. Currently, markers of renal tubular injury are not…”
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Corrigendum to “Development and validation of a multiplexed LC-MS/MS ketone body assay for clinical diagnostics” [J. Mass Spectrom. Adv. Clin. Lab 31 (2024) 49–58] by Kemperman, Robin H.J., Ganetzky, Rebecca D., Master, Stephen R.

“…[This corrects the article DOI: 10.1016/j.jmsacl.2024.01.004.]…”
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Interference from anti-streptavidin antibody by Rulander, Nichole Johnson, Cardamone, David, Senior, Marilyn, Snyder, Peter J, Master, Stephen R

“…Immunoassays are commonly used for clinical diagnosis, although interferences have been well documented. The streptavidin-biotin interaction provides an…”
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Development and validation of a multiplexed LC-MS/MS ketone body assay for clinical diagnostics by Kemperman, Robin H.J., Ganetzky, Rebecca D., Master, Stephen R.

“…•Ketone bodies are critical markers of metabolic status.•Sensitive, reliable mass spectrometry clinical assay was developed to quantify…”
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XPO1 inhibition with selinexor synergizes with proteasome inhibition in neuroblastoma by targeting nuclear export of IkB by Galinski, Basia, Luxemburg, Marcus, Landesman, Yosef, Pawel, Bruce, Johnson, Katherine J., Master, Stephen R., Freeman, Kevin W., Loeb, David M., Hébert, Jean M., Weiser, Daniel A.

“…•XPO1 is overabundant in high-risk neuroblastoma and correlates with poor survival.•Neuroblastoma cells are sensitive to XPO1 inhibition with selinexor.•Use of…”
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How Can We Ensure Reproducibility and Clinical Translation of Machine Learning Applications in Laboratory Medicine? by Haymond, Shannon, Master, Stephen R

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Biochemical characterization of patients with dihydrolipoamide dehydrogenase deficiency by Wongkittichote, Parith, Cuddapah, Sanmati R, Master, Stephen R, Grange, Dorothy K, Dietzen, Dennis, Roper, Stephen M, Ganetzky, Rebecca D

“…Dihydrolipoamide dehydrogenase (DLD; E3) oxidizes lipoic acid. Restoring the oxidized state allows lipoic acid to act as a necessary electron sink for the four…”
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The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor by Fox, Casey J, Hammerman, Peter S, Cinalli, Ryan M, Master, Stephen R, Chodosh, Lewis A, Thompson, Craig B

“…Growth factor withdrawal results in the termination of factor-dependent transcription. One transcript that declines rapidly following growth factor deprivation…”
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Computational expression deconvolution in a complex mammalian organ by Wang, Min, Master, Stephen R, Chodosh, Lewis A

“…Microarray expression profiling has been widely used to identify differentially expressed genes in complex cellular systems. However, while such methods can be…”
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Supervised regularized canonical correlation analysis: integrating histologic and proteomic measurements for predicting biochemical recurrence following prostate surgery by Golugula, Abhishek, Lee, George, Master, Stephen R, Feldman, Michael D, Tomaszewski, John E, Speicher, David W, Madabhushi, Anant

“…Multimodal data, especially imaging and non-imaging data, is being routinely acquired in the context of disease diagnostics; however, computational challenges…”
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Do You See What I See? Automated IFE Interpretation Using Machine Learning by Master, Stephen R, Haymond, Shannon

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Machine Learning in Laboratory Medicine: Recommendations of the IFCC Working Group by Master, Stephen R, Badrick, Tony C, Bietenbeck, Andreas, Haymond, Shannon

“…Abstract Background Machine learning (ML) has been applied to an increasing number of predictive problems in laboratory medicine, and published work to date…”
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Higher Expression of miR-182 in Cytology Specimens of High-Grade Urothelial Cell Carcinoma: A Potential Diagnostic Marker by Wei, Shuanzeng, Bing, Zhanyong, Yao, Yuan, Master, Stephen R., Gupta, Prabodh

“…Objective: MicroRNAs (miRs) are short noncoding RNA molecules that posttranscriptionally modulate protein expression. There are distinct miR alterations…”
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A human model of inflammatory cardio-metabolic dysfunction; a double blind placebo-controlled crossover trial by Mehta, Nehal N, Heffron, Sean P, Patel, Parth N, Ferguson, Jane, Shah, Rachana D, Hinkle, Christine C, Krishnamoorthy, Parasuram, Shah, Rhia, Tabita-Martinez, Jennifer, Terembula, Karen, Master, Stephen R, Rickels, Michael R, Reilly, Muredach P

“…Chronic inflammation may contribute to insulin resistance (IR), metabolic syndrome and atherosclerosis although evidence of causality is lacking in humans. We…”
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Facilitating Test Status Information Communication in the Time of COVID-19 by Master, Stephen R., Neide, Brandy, Kollu, Sunaina, Mulchandani, Surabhi, Harris, Rebecca M., Obstfeld, Amrom E.

“…The Coronavirus 2019 pandemic has strained nearly every aspect of pathology practice, including preanalytic, analytic, and postanalytic processes. Much of the…”
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Pathogens and Patterns: Does the Internet Contain Your Next Biomarker? by Master, Stephen R

“…Throughout recorded human history-all the way from Biblical law codes through recent efforts to contain Ebola outbreaks-information about the status of…”
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Measurement of waist circumference predicts coronary atherosclerosis beyond plasma adipokines by Bose, Subhasish, Krishnamoorthy, Parasuram, Varanasi, Ajay, Nair, Jayamohan, Schutta, Mark, Braunstein, Seth, Iqbal, Nayyar, Schwartz, Stanley, Clair, Caitlin St, Master, Stephen R., Rader, Daniel J., Reilly, Muredach P., Mehta, Nehal N.

“…Objective: The association of plasma adipokines beyond waist circumference (WC) with coronary artery calcification (CAC), a measure of subclinical…”
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A Common, Under-recognized Cause of Elevated Serum Erythropoietin by Babushok, Daria V., MD, PhD, Cardamone, David, MS, MT, Rulander, Nichole, MS, MT, Master, Stephen R., MD, PhD, Hexner, Elizabeth O., MD, MSTR

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Short-chain 3-hydroxyacyl-coenzyme A dehydrogenase associates with a protein super-complex integrating multiple metabolic pathways by Narayan, Srinivas B, Master, Stephen R, Sireci, Anthony N, Bierl, Charlene, Stanley, Paige E, Li, Changhong, Stanley, Charles A, Bennett, Michael J

“…Proteins involved in mitochondrial metabolic pathways engage in functionally relevant multi-enzyme complexes. We previously described an interaction between…”
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