Search Results - "Master, Iqbal"
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A Trial of a Shorter Regimen for Rifampin-Resistant Tuberculosis
Published in The New England journal of medicine (28-03-2019)“…Globally, there are more than 500,000 new infections with drug-resistant tuberculosis each year. In this trial involving patients with rifampin-resistant…”
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Treatment outcomes for extensively drug-resistant tuberculosis and HIV co-infection
Published in Emerging infectious diseases (01-03-2013)“…High mortality rates have been reported for patients co-infected with extensively drug-resistant tuberculosis (XDR-TB) and HIV, but treatment outcomes have not…”
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3
MDR-TB patients in KwaZulu-Natal, South Africa: Cost-effectiveness of 5 models of care
Published in PloS one (18-04-2018)“…South Africa has a high burden of MDR-TB, and to provide accessible treatment the government has introduced different models of care. We report the most…”
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Association between health systems performance and treatment outcomes in patients co-infected with MDR-TB and HIV in KwaZulu-Natal, South Africa: implications for TB programmes
Published in PloS one (01-04-2014)“…To improve the treatment of MDR-TB and HIV co-infected patients, we investigated the relationship between health system performance and patient treatment…”
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5
Surgical Treatment of Complications of Pulmonary Tuberculosis, including Drug-Resistant Tuberculosis
Published in International journal of infectious diseases (01-03-2015)“…Summary Surgery for drug-resistant tuberculosis has been shown to be safe and effective, with similar level of mortalities associated with surgical…”
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Cellular therapy in Tuberculosis
Published in International journal of infectious diseases (01-03-2015)“…Summary Cellular therapy now offer promise of potential adjunct therapeutic options for treatment of drug-resistant tuberculosis (TB). We review here the role…”
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Survival from XDR-TB is associated with modifiable clinical characteristics in rural South Africa
Published in PloS one (06-03-2012)“…Drug-resistant tuberculosis (TB) is a major threat to global public health. Patients with extensively drug-resistant TB (XDR-TB), particularly those with…”
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Extensively drug-resistant tuberculosis in women, KwaZulu-Natal, South Africa
Published in Emerging infectious diseases (01-10-2011)“…To determine whether women in KwaZulu-Natal, South Africa, with drug-resistant tuberculosis (TB) were more likely than men to have extensively drug-resistant…”
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Effect of bedaquiline on mortality in South African patients with drug-resistant tuberculosis: a retrospective cohort study
Published in The lancet respiratory medicine (01-09-2018)“…Addition of bedaquiline to treatment for multidrug-resistant tuberculosis was associated with an increased risk of death in a phase 2b clinical trial,…”
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High treatment success rate for multidrug-resistant and extensively drug-resistant tuberculosis using a bedaquiline-containing treatment regimen
Published in The European respiratory journal (01-12-2018)“…South African patients with rifampicin-resistant tuberculosis (TB) and resistance to fluoroquinolones and/or injectable drugs (extensively drug-resistant (XDR)…”
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Maternal and Infant Outcomes Among Pregnant Women Treated for Multidrug/Rifampicin-Resistant Tuberculosis in South Africa
Published in Clinical infectious diseases (08-04-2021)“…Abstract Background Data on safety and efficacy of second-line tuberculosis drugs in pregnant women and their infants are severely limited due to exclusion…”
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Spatiotemporal Clustering of Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis Is Associated With Human Immunodeficiency Virus Status and Drug-Susceptibility Patterns in KwaZulu-Natal, South Africa
Published in Clinical infectious diseases (06-05-2020)“…Using an open-access spatiotemporal analytics program, we mapped spatiotemporal heterogeneity loci in tuberculosis (TB) cases (clusters) and dynamic changes,…”
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Effectiveness and Cardiac Safety of Bedaquiline-Based Therapy for Drug-Resistant Tuberculosis: A Prospective Cohort Study
Published in Clinical infectious diseases (06-12-2021)“…Abstract Background Bedaquiline improves treatment outcomes in patients with rifampin-resistant (RR) tuberculosis but prolongs the QT interval and carries a…”
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High Incidence of Hospital Admissions With Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis Among South African Health Care Workers
Published in Annals of internal medicine (19-10-2010)“…Nosocomial transmission has been described in extensively drug-resistant tuberculosis (XDR-TB) and HIV co-infected patients in South Africa. However, little is…”
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Improved Survival and Cure Rates With Concurrent Treatment for Multidrug-Resistant Tuberculosis-Human Immunodeficiency Virus Coinfection in South Africa
Published in Clinical infectious diseases (03-04-2018)“…Mortality in multidrug-resistant (MDR) tuberculosis-human immunodeficiency virus (HIV) coinfection has historically been high, but most studies predated the…”
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Responding to SARS-CoV-2 in South Africa: what can we learn from drug-resistant tuberculosis?
Published in The European respiratory journal (01-07-2020)“…The novel coronavirus strain, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was first reported from China in December 2019 [1]. As of 14 May,…”
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Treatment outcomes in patients with drug-resistant TB-HIV co-infection treated with bedaquiline and linezolid
Published in The international journal of tuberculosis and lung disease (01-10-2020)“…BACKGROUND: Bedaquiline (BDQ) has not been extensively studied among patients co-infected with HIV drug-resistant tuberculosis (DR-TB). We compared treatment…”
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The Impact of Concurrent Antiretroviral Therapy and MDR-TB Treatment on Adverse Events
Published in Journal of acquired immune deficiency syndromes (1999) (01-01-2020)“…South Africa has among the highest incidence of multidrug-resistant tuberculosis (MDR-TB) and more than 70% of patients are HIV co-infected. MDR-TB treatment…”
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The Impact of Concurrent Antiretroviral Therapy and MDR-TB Treatment on Adverse Events
Published in Journal of acquired immune deficiency syndromes (1999) (01-01-2020)“…Background: South Africa has among the highest incidence of multidrug-resistant tuberculosis (MDR-TB) and more than 70% of patients are HIV co-infected. MDR-TB…”
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Dilemma of managing asymptomatic children referred with ‘culture-confirmed’ drug-resistant tuberculosis
Published in Archives of disease in childhood (01-07-2016)“…BackgroundThe diagnosis of drug-resistant tuberculosis (DR-TB) in children is challenging and treatment is associated with many adverse effects.ObjectiveWe…”
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