Search Results - "Massimo, C."
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Quercetin and its derivates as antiviral potentials: A comprehensive review
Published in Phytotherapy research (01-01-2022)“…Quercetin, widely distributed in fruits and vegetables, is a flavonoid known for its antioxidant, antiviral, antimicrobial, and antiinflammatory properties…”
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Mechanistic Aspects of the Palladium‐Catalyzed Suzuki‐Miyaura Cross‐Coupling Reaction
Published in Chemistry : a European journal (24-09-2021)“…The story of C−C bond formation includes several reactions, and surely Suzuki‐Miyaura is among the most outstanding ones. Herein, a brief historical overview…”
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Tunable “In-Chain” and “At the End of the Branches” Methyl Acrylate Incorporation in the Polyolefin Skeleton through Pd(II) Catalysis
Published in ACS catalysis (18-03-2022)“…The synthesis of functionalized polyolefins through coordination–insertion polymerization is a highly challenging reaction. The ideal catalyst, in addition to…”
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4
Patterns of Rare and Abundant Marine Microbial Eukaryotes
Published in Current biology (14-04-2014)“…Biological communities are normally composed of a few abundant and many rare species. This pattern is particularly prominent in microbial communities, in which…”
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Marine protist diversity in European coastal waters and sediments as revealed by high-throughput sequencing
Published in Environmental microbiology (01-10-2015)“…Summary Although protists are critical components of marine ecosystems, they are still poorly characterized. Here we analysed the taxonomic diversity of…”
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Large variability of bathypelagic microbial eukaryotic communities across the world’s oceans
Published in The ISME Journal (01-04-2016)“…In this work, we study the diversity of bathypelagic microbial eukaryotes (0.8–20 μm) in the global ocean. Seawater samples from 3000 to 4000 m depth from 27…”
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A fungi hotspot deep in the ocean: explaining the presence of Gjaerumia minor in equatorial Pacific bathypelagic waters
Published in Scientific reports (08-05-2024)“…A plant parasite associated with the white haze disease in apples, the Basidiomycota Gjaerumia minor, has been found in most samples of the global bathypelagic…”
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Update on the Therapeutic Efficacy of Tregs in IBD: Thumbs up or Thumbs down?
Published in Inflammatory bowel diseases (01-10-2017)“…Crohn's disease and ulcerative colitis, the 2 major forms of inflammatory bowel disease (IBD) in humans, arise in genetically predisposed individuals because…”
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Automated flow cytometry as a tool to obtain a fine-grain picture of marine prokaryote community structure along an entire oceanographic cruise
Published in Frontiers in microbiology (06-01-2023)“…On a standard oceanographic cruise, flow cytometry data are usually collected sparsely through a bottle-based sampling and with stations separated by…”
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Response Assessed by Ultrasonography as Target of Biological Treatment for Crohn’s Disease
Published in Clinical gastroenterology and hepatology (01-08-2020)“…Mucosal healing, determined by ileocolonoscopy, is a goal for treatment of Crohn’s disease (CD), but this is an invasive assessment procedure. We investigated…”
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Marked changes in diversity and relative activity of picoeukaryotes with depth in the world ocean
Published in The ISME Journal (01-02-2020)“…Microbial eukaryotes are key components of the ocean plankton. Yet, our understanding of their community composition and activity in different water layers of…”
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Large-scale ocean connectivity and planktonic body size
Published in Nature communications (10-01-2018)“…Global patterns of planktonic diversity are mainly determined by the dispersal of propagules with ocean currents. However, the role that abundance and body…”
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13
JAK inhibitors: an evidence-based choice of the most appropriate molecule
Published in Frontiers in pharmacology (29-10-2024)“…Janus kinase inhibitors (JAKis) represent a fundamental therapeutic tool for the treatment of patients with immune-mediated inflammatory diseases. Although…”
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The Role of Gut Microbiota Biomodulators on Mucosal Immunity and Intestinal Inflammation
Published in Cells (Basel, Switzerland) (16-05-2020)“…Alterations of the gut microbiota may cause dysregulated mucosal immune responses leading to the onset of inflammatory bowel diseases (IBD) in genetically…”
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Multiple Orocutaneous Extraintestinal Manifestations in Ulcerative Colitis Patient: Complete Response to Ustekinumab
Published in Inflammatory bowel diseases (01-09-2023)Get full text
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Mongersen, an Oral SMAD7 Antisense Oligonucleotide, and Crohn’s Disease
Published in The New England journal of medicine (19-03-2015)“…The chronic inflammation of Crohn's disease is caused, at least in part, by repression of TGF-β1 signaling, which is caused by high levels of SMAD7. This trial…”
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Cryo-electron microscopy of extracellular vesicles associated with the marine toxic dinoflagellate Alexandrium minutum
Published in Harmful algae (01-03-2023)“…•The presence of extracellular vesicles was proven with cryo-electron microscopy in a near-axenic culture of the toxic dinoflagellate Alexandrium minutum.•Five…”
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Nonalcoholic fatty liver disease in patients with inflammatory bowel disease: Beyond the natural history
Published in World journal of gastroenterology : WJG (07-10-2019)“…Nonalcoholic fatty liver disease (NAFLD) is a frequently reported condition in patients with inflammatory bowel disease (IBD). Both intestinal inflammation and…”
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Tbet Expression in Regulatory T Cells Is Required to Initiate Th1-Mediated Colitis
Published in Frontiers in immunology (11-09-2019)“…In normal conditions gut homeostasis is maintained by the suppressive activity of regulatory T cells (Tregs), characterized by the expression of the…”
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Phase I Clinical Trial of Smad7 Knockdown Using Antisense Oligonucleotide in Patients With Active Crohn's Disease
Published in Molecular therapy (01-04-2012)“…In the gut of patients with Crohn's disease (CD), high Smad7 blocks the immune-suppressive activity of transforming growth factor (TGF)-β1, thereby…”
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