Search Results - "Massimiliano, Salati"
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Noncoding RNA in Cholangiocarcinoma
Published in Seminars in liver disease (01-02-2019)“…Cholangiocarcinomas (CCAs) are tumors with a dismal prognosis. Early diagnosis is a key challenge because of the lack of specific symptoms, and the curability…”
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2
MicroRNAs (miRNAs) and Long Non-Coding RNAs (lncRNAs) as New Tools for Cancer Therapy: First Steps from Bench to Bedside
Published in Targeted oncology (01-06-2020)“…Non-coding RNAs represent a significant proportion of the human genome. After having been considered as ‘junk’ for a long time, non-coding RNAs are now well…”
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3
Can IDO activity predict primary resistance to anti-PD-1 treatment in NSCLC?
Published in Journal of translational medicine (06-08-2018)“…Immune checkpoint inhibitors have revolutionized the treatment paradigm of highly lethal malignancies like advanced non-small cell lung cancer (NSCLC),…”
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4
Medical treatment for cholangiocarcinoma
Published in Liver international (01-05-2019)“…Most of the patients with cholangiocarcinoma (CCA) present with advanced (inoperable or metastatic) disease, and relapse rates are high in those undergoing…”
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5
A nomogram to predict survival in non-small cell lung cancer patients treated with nivolumab
Published in Journal of translational medicine (27-03-2019)“…The advent of immune checkpoint inhibitors (ICIs) has considerably expanded the armamentarium against non-small cell lung cancer (NSCLC) contributing to…”
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6
Adjuvant chemotherapy in resected bile duct cancer: A systematic review and meta-analysis of randomized trials
Published in Critical reviews in oncology/hematology (01-11-2019)“…•The role of adjuvant chemotherapy for biliary tract cancers is still unclear.•We performed a meta-analysis to assess benefit and risks of adjuvant…”
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The prognostic nutritional index predicts survival and response to first‐line chemotherapy in advanced biliary cancer
Published in Liver international (01-03-2020)“…Background An accurate risk‐stratification is key to optimize the benefit‐to‐risk ratio of palliative treatment in advanced biliary cancer. We aimed at…”
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8
Circulating Tumor DNA in Gastric Adenocarcinoma: Future Clinical Applications and Perspectives
Published in International journal of molecular sciences (29-05-2023)“…Gastric cancer (GC) is still one of the most aggressive cancers with a few targetable alterations and a dismal prognosis. A liquid biopsy allows for…”
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Clinical Significance of Molecular Subtypes in Western Advanced Gastric Cancer: A Real-World Multicenter Experience
Published in International journal of molecular sciences (03-01-2023)“…In recent years, the molecular subtyping of gastric cancer has led to the identification of novel clinically relevant biomarkers as well as promising…”
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10
Ascites and resistance to immune checkpoint inhibition in dMMR/MSI-H metastatic colorectal and gastric cancers
Published in Journal for immunotherapy of cancer (01-02-2022)“…BackgroundDespite unprecedented benefit from immune checkpoint inhibitors (ICIs) in patients with mismatch repair deficient (dMMR)/microsatellite instability…”
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11
Bone Metastases from Intrahepatic Cholangiocarcinoma Confer Worse Prognosis
Published in Current oncology (Toronto) (22-02-2023)“…Metastatic intrahepatic cholangiocarcinoma still has a dismal prognosis. The aim of our study was to investigate the prognostic role of bone metastases in…”
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Integrated Genomics Identifies miR-181/TFAM Pathway as a Critical Driver of Drug Resistance in Melanoma
Published in International journal of molecular sciences (11-02-2021)“…MicroRNAs (miRNAs) are attractive therapeutic targets and promising candidates as molecular biomarkers for various therapy-resistant tumors. However, the…”
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13
Successes and failures of angiogenesis blockade in gastric and gastro-esophageal junction adenocarcinoma
Published in Frontiers in oncology (23-09-2022)“…Gastric and gastro-esophageal junction adenocarcinoma (GEA) remains a considerable major public health problem worldwide, being the fifth most common cancer…”
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A phase II/III randomized clinical trial of CisPlatin plUs Gemcitabine and Nabpaclitaxel (GAP) as pReoperative chemotherapy versus immediate resection in patIents with resecTable BiliarY Tract Cancers (BTC) at high risk for recurrence: PURITY study
Published in BMC cancer (08-04-2024)“…Biliary tract cancers (BTCs) are rare and lethal cancers, with a 5-year survival inferior to 20%(1-3). The only potential curative treatment is surgical…”
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15
The quality of palliative sedation in end-stage disease: audit from a department of oncology and haematology
Published in Supportive care in cancer (01-05-2022)“… Purpose Palliative sedation (PS) plays a critical role to give suffering relief from refractory symptoms at the end of life. Our audit aimed to assess and…”
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Micro-RNA in Cholangiocarcinoma: Implications for Diagnosis, Prognosis, and Therapy
Published in Journal of Molecular Pathology (01-06-2022)“…Bile-duct cancers (BDC) are a group of solid tumors arising from the biliary tree. Despite their classification as rare cancers, the incidence of BDC is…”
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Correction to: A phase II/III randomized clinical trial of CisPlatin plUs Gemcitabine and Nabpaclitaxel (GAP) as pReoperative chemotherapy versus immediate resection in patIents with resecTable BiliarY tract cancers (BTC) at high risk for recurrence: PURITY study
Published in BMC cancer (06-05-2024)Get full text
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18
Irinotecan-based chemotherapy in extrapulmonary neuroendocrine carcinomas: survival and safety data from a multicentric Italian experience
Published in Endocrine (01-12-2021)“…Purpose Neuroendocrine carcinomas (NECs) are a rare subgroup of neuroendocrine neoplasms that occasionally originate from gastro-entero-pancreatic (GEP) tract…”
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Second-Line Chemotherapy for Intrahepatic Cholangiocarcinomas: What Is the Real Gain?
Published in Life (Basel, Switzerland) (01-11-2023)“…The presence of actionable alterations in advanced biliary tract cancer patients opened new therapeutic possibilities for second-line treatments. However, for…”
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Spontaneous Regression of an Inflammatory Myofibroblastic Tumor: A Case Report and a Review of the Literature
Published in Case reports in oncology (01-01-2024)“…Spontaneous tumor regression is the volumetric reduction or complete disappearance of a primary tumor or metastatic sites (single or multiple) without the…”
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