Search Results - "Massimi, P"

Human papillomaviruses, cervical cancer and cell polarity by Thomas, M, Narayan, N, Pim, D, Tomaić, V, Massimi, P, Nagasaka, K, Kranjec, C, Gammoh, N, Banks, L

“…Human papillomaviruses (HPVs) are the causative agents of a number of human cancers, of which cervical cancer is the most important. This occurs following…”
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HPV E6 degradation of p53 and PDZ containing substrates in an E6AP null background by Massimi, P, Shai, A, Lambert, P, Banks, L

“…Human papillomavirus (HPV) type 16 and 18 E6 proteins target many of their cellular substrates for proteasome-mediated degradation. In the case of p53, this is…”
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The cell polarity regulator hScrib controls ERK activation through a KIM site-dependent interaction by Nagasaka, K, Pim, D, Massimi, P, Thomas, M, Tomaić, V, Subbaiah, V K, Kranjec, C, Nakagawa, S, Yano, T, Taketani, Y, Myers, M, Banks, L

“…The cell polarity regulator, human Scribble (hScrib), is a potential tumour suppressor whose loss is a frequent event in late-stage cancer development. Little…”
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Dissection of the C-Terminal Region of E1A Redefines the Roles of CtBP and Other Cellular Targets in Oncogenic Transformation by Cohen, M J, Yousef, A F, Massimi, P, Fonseca, G J, Todorovic, B, Pelka, P, Turnell, A S, Banks, L, Mymryk, J S

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Phosphorylation of the discs large tumour suppressor protein controls its membrane localisation and enhances its susceptibility to HPV E6-induced degradation by MASSIMI, P, NARAYAN, N, CUENDA, A, BANKS, L

“…The Discs Large (Dlg) protein is intimately involved in regulating cell polarity and cell proliferation, and is targeted by the high-risk Human Papillomavirus…”
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Human and primate tumour viruses use PDZ binding as an evolutionarily conserved mechanism of targeting cell polarity regulators by Tomaić, V, Gardiol, D, Massimi, P, Ozbun, M, Myers, M, Banks, L

“…A unique feature of the cancer-causing mucosotropic human papillomaviruses (HPVs) is the ability of their E6 proteins to interact with a number of PDZ…”
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Modeling of salt tectonics by Massimi, P., Quarteroni, A., Saleri, F., Scrofani, G.

“…In this work a general framework for the simulation of sedimentary basins in presence of salt structures is addressed. Sediments and evaporites are modeled as…”
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Differential Phosphorylation of the HPV-16 E7 Oncoprotein during the Cell Cycle by Massimi, Paola, Banks, Lawrence

“…The human papillomavirus type 16 encodes two principal oncoproteins, E6 and E7. The E7 protein has been shown to deregulate the cell cycle through interactions…”
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Human papillomavirus type 16 E7 binds to the conserved carboxy-terminal region of the TATA box binding protein and this contributes to E7 transforming activity by Massimi, P, Pim, D, Banks, L

“…P Massimi, D Pim and L Banks International Centre for Genetic Engineering and Biotechnology, Trieste, Italy. We have previously shown that the human…”
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HPV-16 E7 and adenovirus E1a complex formation with TATA box binding protein is enhanced by casein kinase II phosphorylation by Massimi, P, Pim, D, Storey, A, Banks, L

“…The major transforming protein of HPV-16 is encoded by the E7 gene. This has been shown to cooperate with EJ-ras in the immortalisation of primary rodent cells…”
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Human papillomavirus type 16 E7 impairs the activation of the interferon regulatory factor-1 by Perea, S E, Massimi, P, Banks, L

“…We had previously observed that HPV-16 E7 disturbs the Guanylate Binding Protein (GBP)-ISRE reporter activation by IFN-gamma thus suggesting an alteration of…”
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Adeno-Associated Virus Type 2 Rep Protein Inhibits Human Papillomavirus Type 16 E2 Recruitment of the Transcriptional Coactivator p300 by Marcello, A, Massimi, P, Banks, L, Giacca, M

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Regulation of the human papillomavirus oncoproteins by differential phosphorylation by Massimi, P, Pim, D, Kühne, C, Banks, L

“…Human papillomaviruses (HPVs) are intimately associated with the development of cervical cancer. The virus encodes two oncoproteins, E6 and E7, that are…”
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Neuropeptides in skin from patients with atopic dermatitis: an immunohistochemical study by Pincelli, C, Fantini, F, Massimi, P, Girolomoni, G, Seidenari, S, Giannetti, A

“…The distribution and localization of several neuropeptides were investigated in the lichenified lesions of 11 patients with atopic dermatitis using indirect…”
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Activation of the protein kinase B pathway by the HPV-16 E7 oncoprotein occurs through a mechanism involving interaction with PP2A by PIM, David, MASSIMI, Paola, DILWORTH, Stephen M, BANKS, Lawrence

“…Protein kinase B (PKB) or Akt is one of several second messenger kinases that are activated by cell attachment and growth factor signaling, and that transmit…”
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Mutations in the human papillomavirus type 16 E2 protein identify multiple regions of the protein involved in binding to E1 by Piccini, Antonella, Storey, Alan, Massimi, Paola, Banks, Lawrence

“…1 International Centre for Genetic Engineering and Biotechnology, AREA Science Park, Padriciano 99, I-34012 Trieste, Italy and 2 Department of Experimental…”
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Mutations in the human papillomavirus type 16 E2 protein identify a region of the protein involved in binding to E1 protein by Storey, Alan, Piccini, Antonella, Massimi, Paola, Bouvard, Veronique, Banks, Lawrence

“…International Centre for Genetic Engineering and Biotechnology, Padriciano 99, I-34012 Trieste, Italy Papillomavirus DNA replication is primarily dependent…”
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HPV E6 specifically targets different cellular pools of its PDZ domain-containing tumour suppressor substrates for proteasome-mediated degradation by MASSIMI, Paola, GAMMOH, Noor, THOMAS, Miranda, BANKS, Lawrence

“…The high-risk HPV E6 proteins have been shown to direct the degradation of a variety of cellular proteins that contain PDZ domains. Although some of these…”
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The hScrib Dlg apico-basal control complex is differentially targeted by HPV-16 and HPV-18 E6 proteins by THOMAS, Miranda, MASSIMI, Paola, NAVARRO, Christel, BORG, Jean-Paul, BANKS, Lawrence

“…The E6 proteins of the high-risk Human papillomaviruses (HPV) types have a well-documented ability to target certain cellular proteins for ubiquitin-mediated…”
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Serum IgG subclass concentrations in healthy subjects at different age: age normal percentile charts by PLEBANI, A, UGAZIO, A. G, AVANZINI, M. A, MASSIMI, P, MONAFO, V, BURGIO, G. R

“…IgG subclass levels were determined in 448 normal children from 6 months to 18 years of age and in 141 healthy adults by radial immunodiffusion using…”
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