Search Results - "Massari, Júlio"
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Singlet oxygen generation by the reaction of acrolein with peroxynitrite via a 2-hydroxyvinyl radical intermediate
Published in Free radical biology & medicine (20-05-2020)“…Acrolein (2-propenal) is an environmental pollutant, food contaminant, and endogenous toxic by-product formed in the thermal decomposition and peroxidation of…”
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Generation of Singlet Oxygen by the Glyoxal–Peroxynitrite System
Published in Journal of the American Chemical Society (28-12-2011)“…Diacetyl, methylglyoxal, and glyoxal are α-dicarbonyl catabolites prone to nucleophilic additions of amino groups of proteins and nucleobases, thereby…”
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Acetyl Radical Production by the Methylglyoxal−Peroxynitrite System: A Possible Route for l-Lysine Acetylation
Published in Chemical research in toxicology (15-11-2010)“…Methylglyoxal is an α-oxoaldehyde putatively produced in excess from triose phosphates, aminoacetone, and acetone in some disorders, particularly in diabetes…”
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Electrospray Ionization Mass Spectrometry Applied to Study the Radical Acetylation of Amino Acids, Peptides and Proteins
Published in Journal of the Brazilian Chemical Society (01-12-2013)“…Recently, our group proposed a process that generated acetyl radicals in a reaction medium buffered with a diacetyl/peroxynitrite system. Diacetyl is a…”
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Excited singlet molecular O2 (1Δg) is generated enzymatically from excited carbonyls in the dark
Published in Scientific reports (04-08-2014)“…In mammalian tissues, ultraweak chemiluminescence arising from biomolecule oxidation has been attributed to the radiative deactivation of singlet molecular…”
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Ferricytochrome (c) directly oxidizes aminoacetone to methylglyoxal, a catabolite accumulated in carbonyl stress
Published in PloS one (2013)“…Age-related diseases are associated with increased production of reactive oxygen and carbonyl species such as methylglyoxal. Aminoacetone, a putative threonine…”
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Ferricytochrome c Directly Oxidizes Aminoacetone to Methylglyoxal, a Catabolite Accumulated in Carbonyl Stress
Published in PloS one (06-03-2013)“…Age-related diseases are associated with increased production of reactive oxygen and carbonyl species such as methylglyoxal. Aminoacetone, a putative threonine…”
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Radical Acetylation of 2′-Deoxyguanosine and l-Histidine Coupled to the Reaction of Diacetyl with Peroxynitrite in Aerated Medium
Published in Chemical research in toxicology (01-04-2008)“…Diacetyl, like other α-dicarbonyl compounds, is reportedly cytotoxic and genotoxic. A food and cigarette contaminant, it is related with alcohol hepatotoxicity…”
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