Search Results - "Massa, Mark A."

Systematic Investigation of EDC/sNHS-Mediated Bioconjugation Reactions for Carboxylated Peptide Substrates by Totaro, Kyle A, Liao, Xiaoli, Bhattacharya, Keshab, Finneman, Jari I, Sperry, Justin B, Massa, Mark A, Thorn, Jennifer, Ho, Sa V, Pentelute, Bradley L

“…1-Ethyl-3-(3-(dimethylamino)­propyl)­carbodiimide (EDC) bioconjugations have been utilized in preparing variants for medical research. While there have been…”
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Effects of Conformational Changes in Peptide–CRM197 Conjugate Vaccines by Jaffe, Jake, Wucherer, Kristin, Sperry, Justin, Zou, Qin, Chang, Qing, Massa, Mark A, Bhattacharya, Keshab, Kumar, Sandeep, Caparon, Maire, Stead, David, Wright, Paul, Dirksen, Anouk, Francis, Matthew B

“…Conjugate vaccines prepared with the cross-reactive material 197 (CRM197) carrier protein have been successful in the clinic and are of great interest in the…”
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Effects of Conformational Changes in Peptide-CRM 197 Conjugate Vaccines by Jaffe, Jake, Wucherer, Kristin, Sperry, Justin, Zou, Qin, Chang, Qing, Massa, Mark A, Bhattacharya, Keshab, Kumar, Sandeep, Caparon, Maire, Stead, David, Wright, Paul, Dirksen, Anouk, Francis, Matthew B

“…Conjugate vaccines prepared with the cross-reactive material 197 (CRM ) carrier protein have been successful in the clinic and are of great interest in the…”
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Discovery of a Simple Picomolar Inhibitor of Cholesteryl Ester Transfer Protein by Reinhard, Emily J, Wang, Jane L, Durley, Richard C, Fobian, Yvette M, Grapperhaus, Margaret L, Hickory, Brian S, Massa, Mark A, Norton, Monica B, Promo, Michele A, Tollefson, Michael B, Vernier, William F, Connolly, Daniel T, Witherbee, Bryan J, Melton, Michele A, Regina, Karen J, Smith, Mark E, Sikorski, James A

“…A novel series of substituted N-[3-(1,1,2,2-tetrafluoroethoxy)benzyl]-N-(3-phenoxyphenyl)-trifluoro-3-amino-2-propanols is described which potently and…”
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Thiometalate complexes containing arene, thiophene, and cyclobutadiene coligands. Are thiometalate clusters good models for desulfurization catalysts? by Howard, Kevin E, Lockemeyer, John R, Massa, Mark A, Rauchfuss, Thomas B, Wilson, Scott R, Yang, Xiaoguang

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Novel heteroaryl replacements of aromatic 3-tetrafluoroethoxy substituents in trifluoro-3-(tertiaryamino)-2-propanols as potent inhibitors of cholesteryl ester transfer protein by Massa, Mark A., Spangler, Dale P., Durley, Richard C., Hickory, Brian S., Connolly, Daniel T., Witherbee, Bryan J., Smith, Mark E., Sikorski, James A.

“…A series of novel N, N-disubstituted trifluoro-3-amino-2-propanols has been prepared as potent inhibitors of cholesteryl ester transfer protein (CETP)…”
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Functionalization of Cp4Fe4(CO)4:  Contrasts and Comparisons with Ferrocene by Westmeyer, Mark D, Massa, Mark A, Rauchfuss, Thomas B, Wilson, Scott R

“…Thermolysis of a xylene solution of Cp2Fe2(CO)4 and PPh3 yields primarily Cp4Fe4(CO)4 (1) together with smaller amounts of (C5H4Ph)Cp3Fe4(CO)4 and…”
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Chiral N,N-Disubstituted Trifluoro-3-Amino-2-Propanols Are Potent Inhibitors of Cholesteryl Ester Transfer Protein by Durley, Richard C, Grapperhaus, Margaret L, Hickory, Brian S, Massa, Mark A, Wang, Jane L, Spangler, Dale P, Mischke, Deborah A, Parnas, Barry L, Fobian, Yvette M, Rath, Nigam P, Honda, Dorothy D, Zeng, Ming, Connolly, Daniel T, Heuvelman, Deborah M, Witherbee, Bryan J, Melton, Michele A, Glenn, Kevin C, Krul, Elaine S, Smith, Mark E, Sikorski, James A

“…A novel series of substituted N-benzyl-N-phenyl-trifluoro-3-amino-2-propanols are described that reversibly inhibit cholesteryl ester transfer protein (CETP)…”
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The total synthesis of the natural product endothelin converting enzyme (ECE) inhibitor, WS75624 B by Patt, William C., Massa, Mark A.

“…The first total synthesis of WS75624 B, 1, an endothelin converting enzyme inhibitor produced in a fermentation broth of Saccharothrix sp. No. 75624 is…”
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Effects of Conformational Changes in Peptide–CRM^sub 197^ Conjugate Vaccines by Jaffe, Jake, Wucherer, Kristin, Sperry, Justin, Zou, Qin, Chang, Qing, Massa, Mark A, Bhattacharya, Keshab, Kumar, Sandeep, Caparon, Maire, Stead, David, Wright, Paul, Dirksen, Anouk, Francis, Matthew B

“…Conjugate vaccines prepared with the cross-reactive material 197 (CRM197) carrier protein have been successful in the clinic and are of great interest in the…”
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Synthesis of 3‘‘-Desmethoxyazithromycin:  Regioselectivity and Stereoselectivity of SmI2-Mediated α-Deoxygenation Reaction by Yang, Bingwei V, Massa, Mark A

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Butenolide Endothelin Antagonists with Improved Aqueous Solubility by Patt, William C, Cheng, Xue-Min, Repine, Joseph T, Lee, Chet, Reisdorph, Bill R, Massa, Mark A, Doherty, Annette M, Welch, Kathleen M, Bryant, John W, Flynn, Michael A, Walker, Donnelle M, Schroeder, Richard L, Haleen, Stephen J, Keiser, Joan A

“…Continued development around our ETA-selective endothelin (ET) antagonist 1 (CI-1020) has led to the synthesis of analogues with improved aqueous solubility…”
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Synthesis of the functionalized cluster (CH:CH2C5H4)Cp3Fe4(CO)4 and its incorporation into poly(methyl methacrylate) by Massa, Mark A, Rauchfuss, Thomas B

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A unidentate thiometalate complex: (MeCp)(dppe)Ru-S-ReS3 [bis(diphenylphosphinoethane][methyl cyclopentadienyl-.mu.-sulfidotrisulfidorheniumruthenium] by Massa, Mark A, Rauchfuss, Thomas B, Wilson, Scott R

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3-Methyl-4H-[1,2,4]-oxadiazol-5-one: a versatile synthon for protecting monosubstituted acetamidines by Moormann, Alan E., Wang, Jane L., Palmquist, Katherine E., Promo, Michele A., Snyder, Jeffery S., Scholten, Jeffrey A., Massa, Mark A., Sikorski, James A., Webber, R. Keith

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3-Methyl-4 H-[1,2,4]-oxadiazol-5-one: a versatile synthon for protecting monosubstituted acetamidines by Moormann, Alan E., Wang, Jane L., Palmquist, Katherine E., Promo, Michele A., Snyder, Jeffery S., Scholten, Jeffrey A., Massa, Mark A., Sikorski, James A., Webber, R. Keith

“…The utilization of 3-methyl-4 H-[1,2,4]-oxadiazol-5-one as a versatile protected acetamidine is demonstrated through employment in a variety of synthetic…”
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Synthesis of 3‘‘-Desmethoxyazithromycin:  Regioselectivity and Stereoselectivity of SmI 2 -Mediated α-Deoxygenation Reaction by Yang, Bingwei V., Massa, Mark A.

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Discovery of Chiral N,N-Disubstituted Trifluoro-3-amino-2-propanols as Potent Inhibitors of Cholesteryl Ester Transfer Protein by Durley, Richard C, Grapperhaus, Margaret L, Massa, Mark A, Mischke, Deborah A, Parnas, Barry L, Fobian, Yvette M, Rath, Nigam P, Honda, Dorothy D, Zeng, Ming, Connolly, Daniel T, Heuvelman, Deborah M, Witherbee, Bryan J, Glenn, Kevin C, Krul, Elaine S, Smith, Mark E, Sikorski, James A

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Functionalization of Cp 4 Fe 4 (CO) 4 :  Contrasts and Comparisons with Ferrocene by Westmeyer, Mark D., Massa, Mark A., Rauchfuss, Thomas B., Wilson, Scott R.

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Synthesis of novel substituted pyridines as inhibitors of endothelin coverting enzyme-1 (ECE-1) by Massa, Mark A., Patt, William C., Ahn, Kyunghye, Sisneros, Andre M., Herman, Sarah B., Doherty, Annette

“…A series of bi-aryl pyridine carboxylic acids has been prepared and evaluated as inhibitors of ECE-1. The analogs were prepared by Pd catalyzed cross couplings…”
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