Search Results - "Massa, Christopher"
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Histologic and biochemical alterations predict pulmonary mechanical dysfunction in aging mice with chronic lung inflammation
Published in PLoS computational biology (01-08-2017)“…Both aging and chronic inflammation produce complex structural and biochemical alterations to the lung known to impact work of breathing. Mice deficient in…”
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2
Acute chlorine gas exposure produces transient inflammation and a progressive alteration in surfactant composition with accompanying mechanical dysfunction
Published in Toxicology and applied pharmacology (01-07-2014)“…Acute Cl2 exposure following industrial accidents or military/terrorist activity causes pulmonary injury and severe acute respiratory distress. Prior studies…”
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3
Biological Mechanisms of S-Nitrosothiol Formation and Degradation: How Is Specificity of S-Nitrosylation Achieved?
Published in Antioxidants (12-07-2021)“…The modification of protein cysteine residues underlies some of the diverse biological functions of nitric oxide (NO) in physiology and disease. The formation…”
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4
Implementation of an electroencephalogram‐guided propofol anesthesia education program in an academic pediatric anesthesia practice
Published in Pediatric anesthesia (01-11-2022)“…Background Propofol total intravenous anesthesia (TIVA) is increasingly popular in pediatric anesthesia, but education on its use is variable and over‐dosage…”
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Implementation of an electroencephalogram‐guided propofol anesthesia practice in a large academic pediatric hospital: A quality improvement project
Published in Pediatric anesthesia (01-02-2024)“…Background Propofol‐based total intravenous anesthesia is gaining popularity in pediatric anesthesia. Electroencephalogram can be used to guide propofol dosing…”
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6
Ozone-induced injury and oxidative stress in bronchiolar epithelium are associated with altered pulmonary mechanics
Published in Toxicological sciences (01-06-2013)“…In these studies, we analyzed the effects of ozone on bronchiolar epithelium. Exposure of rats to ozone (2 ppm, 3 h) resulted in rapid (within 3 h) and…”
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7
Pentoxifylline attenuates nitrogen mustard-induced acute lung injury, oxidative stress and inflammation
Published in Experimental and molecular pathology (01-08-2014)“…Nitrogen mustard (NM) is a toxic alkylating agent that causes damage to the respiratory tract. Evidence suggests that macrophages and inflammatory mediators…”
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8
Prolonged injury and altered lung function after ozone inhalation in mice with chronic lung inflammation
Published in American journal of respiratory cell and molecular biology (01-12-2012)“…Surfactant protein-D (Sftpd) is a pulmonary collectin important in down-regulating macrophage inflammatory responses. In these experiments, we analyzed the…”
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9
Age-related increases in ozone-induced injury and altered pulmonary mechanics in mice with progressive lung inflammation
Published in American journal of physiology. Lung cellular and molecular physiology (15-10-2013)“…In these studies we determined whether progressive pulmonary inflammation associated with aging in surfactant protein D (Sftpd)-/- mice leads to an exacerbated…”
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10
Modeling the dynamics of recruitment and derecruitment in mice with acute lung injury
Published in Journal of applied physiology (1985) (01-12-2008)“…1 Bioengineering Program, College of Engineering and Mathematical Sciences and 2 Vermont Lung Center, Department of Medicine, University of Vermont,…”
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11
The role of inducible nitric oxide synthase for interstitial remodeling of alveolar septa in surfactant protein D-deficient mice
Published in American journal of physiology. Lung cellular and molecular physiology (01-11-2015)“…Surfactant protein D (SP-D) modulates the lung's immune system. Its absence leads to NOS2-independent alveolar lipoproteinosis and NOS2-dependent chronic…”
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12
Low-dose AgNPs reduce lung mechanical function and innate immune defense in the absence of cellular toxicity
Published in Nanotoxicology (02-01-2016)“…Multiple studies have examined the direct cellular toxicity of silver nanoparticles (AgNPs). However, the lung is a complex biological system with multiple…”
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13
Exposure to Silver Nanospheres Leads to Altered Respiratory Mechanics and Delayed Immune Response in an in Vivo Murine Model
Published in Frontiers in pharmacology (26-03-2018)“…Here we examine the organ level toxicology of both carbon black (CB) and silver nanoparticles (AgNP). We aim to determine metal-specific effects to respiratory…”
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14
Multimodality molecular imaging of the alveolar-capillary barrier in lung disease using albumin based optical and PET tracers
Published in Molecular biomedicine (20-12-2020)“…Inflammatory changes caused by viruses, bacteria, exposure to toxins, commonly used drugs and even surgical intervention have the potential of causing abnormal…”
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15
Reliability of estimating stochastic lung tissue heterogeneity from pulmonary impedance spectra: a forward-inverse modeling study
Published in Annals of biomedical engineering (01-10-2007)“…Heterogeneity of regional lung mechanics is an important determinant of the work of breathing and may be a risk factor for ventilator associated lung injury…”
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16
Reliability of Estimating Stochastic Lung Tissue Heterogeneity from Pulmonary Impedance Spectra: A Forward-Inverse Modeling Study
Published in Annals of biomedical engineering (01-10-2007)“…The online version of the original article can be found under doi: 10.1007/s10439-007-9339-1…”
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17
Parenchymal and Inflammatory Cell Responses to Single and Repeated Ozone Exposure in Healthy and Surfactant Protein-C Mutant Lung
Published in Toxicological sciences (25-08-2022)“…Abstract Mutations in the alveolar epithelial-specific gene encoding for surfactant protein C (SP-C) are linked to pulmonary disease. Ozone (O3) is a…”
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18
A Transcription for Piccolo Trumpet With Historical Context and Methodology: Oboe Quartet KV 370/368b by Wolfgang Amadeus Mozart
Published 01-01-2024“…This document explores the challenges of transcribing Mozart's Oboe Quartet for piccolo trumpet, emphasizing performance practices. Both oboe and trumpet…”
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Dissertation -
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Multisystem Inflammatory Syndrome in Children (MIS-C): Experiences With a New Disease Process
Published in Journal of neurosurgical anesthesiology (01-01-2022)“…On March 20, 2021, the Columbia University Department of Anesthesiology hosted the Papper virtual event dedicated to an academic discussion of various aspects…”
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Histologic and biochemical alterations predict mechanical dysfunction in aging and chronically inflamed mice (717.4)
Published in The FASEB journal (01-04-2014)“…Aging produces structural and biochemical alterations to the lung, which impact work of breathing. Mice deficient in surfactant protein D (SP‐D) develop…”
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