Search Results - "Masood Husain"

One-Pot Multienzyme Cascades for Stereodivergent Synthesis of Tetrahydroquinolines by Husain, Syed Masood, De, Arijit, Shukla, Ajeet

“…The tetrahydroquinoline (THQ) framework is commonly found in natural products and pharmaceutically relevant molecules. Apart from the use of transition metal…”
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A Redox‐Based Superoxide Generation System Using Quinone/Quinone Reductase by Singh, Shailesh Kumar, Husain, Syed Masood

“…Superoxide (O2.−) generation in biological systems is achieved through some of the most complex enzymatic systems. Of these, only xanthine/xanthine oxidase has…”
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Synthesis of rhein and diacerein: a chemoenzymatic approach using anthrol reductase of Talaromyces islandicus by Rajput, Anshul, Mondal, Amit, Pandey, Satyendra Kumar, Husain, Syed Masood

“…Herein, we report two methods for the synthesis of the osteoarthritis drug rhein and its prodrug diacerein using a chemoenzymatic approach. The strategy relies…”
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Chemoenzymatic total synthesis of nodulones C and D using a naphthol reductase of Magnaporthe grisea by Manna, Tanaya, Rajput, Anshul, Saha, Nirmal, Mondal, Amit, Debnath, Subhas Chandra, Husain, Syed Masood

“…Herein, the asymmetric and chemoenzymatic synthesis of ( )-nodulone C, -nodulone D and related ( )-dihydronaphthalenone is reported. It involves multistep…”
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A Biomimetic Synthesis of Racemic Dihydroanthracen‐1(2H)‐ones Using Sodium Borohydride in Water by Mondal, Amit, Singh, Shailesh Kumar, Saha, Nirmal, Husain, Syed Masood

“…Herein, we report a single step synthesis of racemic dihydroanthracenones by the reduction of anthraquinones using NaBH4 and Na2S2O4 in water. The racemic…”
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Global Incidence and Mortality Trends due to Adverse Effects of Medical Treatment, 1990-2017: A Systematic Analysis from the Global Burden of Diseases, Injuries and Risk Factors Study by Nauman, Javaid, Soteriades, Elpidoforos S, Hashim, Muhammad Jawad, Govender, Romona, Al Darmaki, Reem Saif, Al Falasi, Reem Juma, Ojha, Shreesh Kumar, Masood-Husain, Shamaila, Javaid, Syed Fahad, Khan, Moien Ab

“…Aim To quantify the global incidence and mortality of adverse effects of medical treatment (AEMT) and forecast the possible emerging trends of AEMT. Materials…”
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Chemoenzymatic reduction of citreorosein and its implications on aloe-emodin and rugulosin C (bio)synthesis by Mondal, Amit, Saha, Nirmal, Rajput, Anshul, Singh, Shailesh Kumar, Roy, Brindaban, Husain, Syed Masood

“…A chemoenzymatic reduction of citreorosein by the NADPH-dependent polyhydroxyanthracene reductase from Cochliobolus lunatus or MdpC from Aspergillus nidulans…”
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Insights into the Role of Ketoreductases in the Biosynthesis of Partially Reduced Bacterial Aromatic Polyketides by Husain, Syed Masood, Präg, Andreas, Linnenbrink, Anton, Bechthold, Andreas, Müller, Michael

“…Partially reduced aromatic polyketides are bioactive secondary metabolites or intermediates in the biosynthesis of deoxygenated aromatics. For the antibiotic…”
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Unprecedented Role of Hydronaphthoquinone Tautomers in Biosynthesis by Husain, Syed Masood, Schätzle, Michael A., Lüdeke, Steffen, Müller, Michael

“…Quinones and hydroquinones are among the most common cellular cofactors, redox mediators, and natural products. Here, we report on the reduction of…”
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Global Trends and Forecast of the Burden of Adverse Effects of Medical Treatment: Epidemiological Analysis Based on the Global Burden of Disease Study by Khan, Moien Ab, Soteriades, Elpidoforos S, King, Jeff, Govender, Romona, Hashim, Muhammad Jawad, Masood-Husain, Shamaila, Javaid, Syed Fahad, Debaib Mohammed Saeed Al Darei, Shaikha, Dahi Al Sheryani, Shamma, Nauman, Javaid

“…Aim To quantify and update the years of life lost (YLL), years lived with disability (YLD) and disability-adjusted life years (DALY) due to the adverse effects…”
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Concise chemoenzymatic total synthesis of (−)-rubroskyrin, (−)-deoxyrubroskyrin (−)-luteoskyrin, and (−)-deoxyluteoskyrin by Mondal, Amit, Saha, Nirmal, Husain, Syed Masood

“…Synthesis of complex dimeric natural products (−)-luteoskyrin and (−)-deoxyluteoskyrin isolated from P. islandicum Sopp nearly 70 years ago, remained a…”
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Tautomers of Anthrahydroquinones: Enzymatic Reduction and Implications for Chrysophanol, Monodictyphenone, and Related Xanthone Biosyntheses by Schätzle, Michael A, Husain, Syed Masood, Ferlaino, Sascha, Müller, Michael

“…Reduction of emodin by sodium dithionite resulted in the formation of two tautomeric forms of emodin hydroquinone. Subsequent conversion by the short-chain…”
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Tetrahydroxynaphthalene Reductase: Catalytic Properties of an Enzyme Involved in Reductive Asymmetric Naphthol Dearomatization by Schätzle, Michael A., Flemming, Stephan, Husain, Syed Masood, Richter, Michael, Günther, Stefan, Müller, Michael

“…In reduced circumstances: Tetrahydroxynaphthalene reductase shows a broad substrate range including alternate phenolic compounds and cyclic ketones. Structural…”
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Microwave assisted synthesis of 3-benzazepin-2-ones as building blocks for 2,3-disubstituted tetrahydro-3-benzazepines by Sarkar, Soumya, Husain, Syed Masood, Schepmann, Dirk, Fröhlich, Roland, Wünsch, Bernhard

“…Microwave assisted condensation of primary amines with keto acids 1a–c provided directly 3,4-disubstituted 1,3-dihydro-3-benzazepin-2-ones 2. Whereas small…”
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Biomimetic Asymmetric Synthesis of (R)-GTRI-02 and (3S,4R)-3,4-Dihydroxy-3,4-dihydronaphthalen-1(2H)-ones by Husain, Syed Masood, Schätzle, Michael A, Röhr, Caroline, Lüdeke, Steffen, Müller, Michael

“…The NADPH-dependent tetrahydroxynaphthalene reductase (T4HNR) from Magnaporthe grisea was used for the biomimetic synthesis of (R)-GTRI-02 by stereoselective…”
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Stereoselective Reduction of 2-Hydroxy Ketones towards syn- and anti-1,2-Diols by Husain, Syed Masood, Stillger, Thomas, Dünkelmann, Pascal, Lödige, Melanie, Walter, Lydia, Breitling, Elke, Pohl, Martina, Bürchner, Mara, Krossing, Ingo, Müller, Michael, Romano, Diego, Molinari, Francesco

“…Stereoselective reduction of 2‐hydroxy ketones should in principle give access to syn‐ and anti‐1,2‐diols. anti‐1,2‐Diols are accessible in a highly selective…”
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One‐Pot Multienzyme Cascades for Stereodivergent Synthesis of Tetrahydroquinolines by De, Arijit, Shukla, Ajeet, Masood Husain, Syed

“…Abstract The tetrahydroquinoline (THQ) framework is commonly found in natural products and pharmaceutically relevant molecules. Apart from using transition…”
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Unprecedented Role of Hydronaphthoquinone Tautomers in Biosynthesis by Husain, Syed Masood, Schätzle, Michael A., Lüdeke, Steffen, Müller, Michael

“…Quinones and hydroquinones are among the most common cellular cofactors, redox mediators, and natural products. Here, we report on the reduction of…”
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Syed Masood Husain

“…"My long-term goal is to popularize biocatalysis in India so that more and more people work in this area and invent new-to-nature chemistry… If I could have…”
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Fosfomycin: A Substitute in Therapeutic Options for Extended Spectrum Beta-lactamase Producing Uropathogens by Faiza Zeeshan et al, Syed Mehmood Hasan, Asma Shabbir, Amber Ilyas, Syed Muhammad Hasan, Masood Husain

“…Background: The emergence of antibiotic resistance among pathogens causing urinary tract infections (UTI) has made treatment options limited. The use of…”
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