Search Results - "Mason, Kathryn"
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MK-1775, a Novel Wee1 Kinase Inhibitor, Radiosensitizes p53-Defective Human Tumor Cells
Published in Clinical cancer research (01-09-2011)“…Radiotherapy is commonly used to treat a variety of solid tumors. However, improvements in the therapeutic ratio for several disease sites are sorely needed,…”
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2
Investigating the Impact of a Musical Intervention on Preschool Children's Executive Function
Published in Frontiers in psychology (20-12-2018)“…The impact of music interventions on the cognitive skills of young children has become the focus of a growing number of research studies in recent years. This…”
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3
p16 Represses DNA Damage Repair via a Novel Ubiquitin-Dependent Signaling Cascade
Published in Cancer research (Chicago, Ill.) (01-03-2022)“…Squamous cell carcinoma driven by human papillomavirus (HPV) is more sensitive to DNA-damaging therapies than its HPV-negative counterpart. Here, we show that…”
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4
How Does Task Presentation Impact Motor Inhibition Performance in Young Children?
Published in Frontiers in psychology (02-08-2021)“…Peg tapping tasks are commonly used as a measure of inhibitory skill in young children. However, differences in the way the task is presented may influence…”
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5
Targeting DNA damage response in head and neck cancers through abrogation of cell cycle checkpoints
Published in International journal of radiation biology (03-08-2021)“…Head and neck cancers (HNSCC) are routinely treated with radiotherapy; however, normal tissue toxicity remains a concern. Therefore, it is important to…”
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Enteral Activation of WR-2721 Mediates Radioprotection and Improved Survival from Lethal Fractionated Radiation
Published in Scientific reports (13-02-2019)“…Unresectable pancreatic cancer is almost universally lethal because chemotherapy and radiation cannot completely stop the growth of the cancer. The major…”
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Tumor Induction in Mice After Localized Single- or Fractionated-Dose Irradiation: Differences in Tumor Histotype and Genetic Susceptibility Based on Dose Scheduling
Published in International journal of radiation oncology, biology, physics (15-07-2015)“…Purpose To investigate differences in tumor histotype, incidence, latency, and strain susceptibility in mice exposed to single-dose or clinically relevant,…”
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Cyclo-oxygenase-2 and its inhibition in cancer : Is there a role?
Published in Drugs (New York, N.Y.) (01-01-2007)“…Despite recent improvements in chemotherapy and radiation therapy in cancer management with the addition of biological agents, novel treatment approaches are…”
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Musical Activities, Prosocial Behaviors, and Executive Function Skills of Kindergarten Children
Published in Music & science (01-12-2021)“…Prosocial behaviors and executive function are staples of child development. Engagement in music has been associated with enhanced prosocial behaviors and…”
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10
The Withers Archive: online availability of H. Rodney Withers' data
Published in International journal of radiation biology (01-12-2016)“…We have collected lab notebooks from Rod Wither's many years of experimentation, from laboratories in Houston and Los Angeles, as well as from several of his…”
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Targeting Toll-like Receptor 9 with CpG Oligodeoxynucleotides Enhances Tumor Response to Fractionated Radiotherapy
Published in Clinical cancer research (01-01-2005)“…Synthetic oligodeoxynucleotides containing unmethylated CpG motifs detected by Toll-like receptor 9 of dendritic cells and B cells have potent immunomodulatory…”
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12
130-nm Albumin–Bound Paclitaxel Enhances Tumor Radiocurability and Therapeutic Gain
Published in Clinical cancer research (15-03-2007)“…Purpose: 130-nm albumin–bound paclitaxel (nab-paclitaxel) is a novel solvent-free albumin-bound paclitaxel, designed to avoid solvent-related toxicity…”
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13
CpG oligodeoxynucleotides are potent enhancers of radio- and chemoresponses of murine tumors
Published in Radiotherapy and oncology (01-08-2006)“…Synthetic oligodeoxynucleotides (ODNs) containing unmethylated cytosine-guanine (CpG) motifs bind to Toll-like receptor 9 (TLR9) and stimulate both innate and…”
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14
The Impact of Timing of EGFR and IGF-1R Inhibition for Sensitizing Head and Neck Cancer to Radiation
Published in Anticancer research (01-08-2012)“…Targeting the epidermal growth factor receptor (EGFR) improved radiotherapy outcome by 10-15% in head and neck tumors (HNSCC). We tested the therapeutic…”
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INO-1001, a novel inhibitor of poly(ADP-ribose) polymerase, enhances tumor response to doxorubicin
Published in Investigational new drugs (01-02-2008)“…Summary Poly(ADP-ribose) synthetase inhibitor, INO-1001, is known to sensitize cells to radiation in vitro by inhibiting the repair of DNA damage. Recent…”
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CpG oligodeoxynucleotide enhances tumor response to radiation
Published in Cancer research (Chicago, Ill.) (01-08-2004)“…CpG oligodeoxynucleotides (ODNs) are synthetic DNA sequences containing unmethylated cytosine-guanine motifs with potent immunomodulatory effects. Via…”
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Inhibition of P-TEFb by DRB suppresses SIRT1/CK2α pathway and enhances radiosensitivity of human cancer cells
Published in Anticancer research (01-12-2014)“…Positive transcription elongation factor-b (P-TEFb) is a complex containing CDK9 and a cyclin (T1, T2 or K). The effect of inhibition of P-TEFb by…”
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Potentiation of tumor response to radiation or chemoradiation by selective cyclooxygenase-2 enzyme inhibitors
Published in International journal of radiation oncology, biology, physics (01-02-2004)“…Cyclooxygenase-2 (COX-2) is an enzyme expressed primarily in pathologic states, such as inflammatory disorders and cancer, where it mediates prostaglandin…”
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Poly (ADP-ribose) Polymerase Inhibitors in Cancer Treatment
Published in American journal of clinical oncology (01-02-2014)“…Recent research on inhibitors of poly (ADP-ribose) polymerase (PARP) has demonstrated their potential for improving cancer therapy. They inhibit protein poly…”
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Preclinical Biologic Assessment of Proton Beam Relative Biologic Effectiveness at Proton Therapy Center Houston
Published in International journal of radiation oncology, biology, physics (15-07-2007)“…The clinical use of protons for the treatment of cancer is one of the most technologically advanced forms of therapy. The newly commissioned M.D. Anderson…”
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