Search Results - "Mason, John O."

Pax6 mutant cerebral organoids partially recapitulate phenotypes of Pax6 mutant mouse strains by Ferdaos, Nurfarhana, Lowell, Sally, Mason, John O

“…Cerebral organoids show great promise as tools to unravel the complex mechanisms by which the mammalian brain develops during embryogenesis. We generated mouse…”
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Cerebral organoids as tools to identify the developmental roots of autism by Chan, Wai Kit, Griffiths, Rosie, Price, David J, Mason, John O

“…Abstract Some autism spectrum disorders (ASD) likely arise as a result of abnormalities during early embryonic development of the brain. Studying human…”
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The transcription factor E2A drives neural differentiation in pluripotent cells by Rao, Chandrika, Malaguti, Mattias, Mason, John O, Lowell, Sally

“…The intrinsic mechanisms that link extracellular signalling to the onset of neural differentiation are not well understood. In pluripotent mouse cells, BMP…”
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Regulation of cerebral cortical neurogenesis by the Pax6 transcription factor by Manuel, Martine N, Mi, Da, Mason, John O, Price, David J

“…Understanding brain development remains a major challenge at the heart of understanding what makes us human. The neocortex, in evolutionary terms the newest…”
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Vitrectomy and Vitrector Port Needle Biopsy of Choroidal Melanoma for Gene Expression Profile Testing Immediately before Brachytherapy by Reddy, Deepthi M., MD, Mason, Lauren B., BS, Mason, John O., MD, Crosson, Jason N., MD, Yunker, Jacob J., MD

“…Purpose Transvitreal and transscleral needle biopsy can result in complications including vitreous hemorrhage and retinal detachment. This study evaluated a…”
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Pax6 Exerts Regional Control of Cortical Progenitor Proliferation via Direct Repression of Cdk6 and Hypophosphorylation of pRb by Mi, Da, Carr, Catherine B., Georgala, Petrina A., Huang, Yu-Ting, Manuel, Martine N., Jeanes, Emily, Niisato, Emi, Sansom, Stephen N., Livesey, Frederick J., Theil, Thomas, Hasenpusch-Theil, Kerstin, Simpson, T. Ian, Mason, John O., Price, David J.

“…The mechanisms by which early spatiotemporal expression patterns of transcription factors such as Pax6 regulate cortical progenitors in a region-specific…”
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Long-Term Outcomes of Vitrectomy for Idiopathic Epiretinal Membrane With Internal Limiting Membrane Removal in Patients With Good Preoperative Visual Acuity by Drummond, Sean C., Crosson, Jason N., Mason, John O.

“…Purpose: To evaluate the long-term visual results of vitrectomy with epiretinal membrane (ERM) and internal limiting membrane (ILM) removal for idiopathic ERM…”
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Foxg1 is required for specification of ventral telencephalon and region-specific regulation of dorsal telencephalic precursor proliferation and apoptosis by Martynoga, Ben, Morrison, Harris, Price, David J., Mason, John O.

“…Null mutation of the Foxg1 gene causes hypoplasia of the mouse telencephalon and loss of ventral telencephalic structures. We show that a crucial early…”
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Safety, efficacy, and quality of life following sutureless vitrectomy for symptomatic vitreous floaters by Mason, 3rd, John O, Neimkin, Michael G, Mason, 4th, John O, Friedman, Duncan A, Feist, Richard M, Thomley, Martin L, Albert, Michael A

“…To determine the safety, efficacy, and quality of life improvement following sutureless 25-gauge pars plana vitrectomy for symptomatic floaters. Patients with…”
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Pax6 limits the competence of developing cerebral cortical cells to respond to inductive intercellular signals by Manuel, Martine, Tan, Kai Boon, Kozic, Zrinko, Molinek, Michael, Marcos, Tiago Sena, Razak, Maizatul Fazilah Abd, Dobolyi, Dániel, Dobie, Ross, Henderson, Beth E P, Henderson, Neil C, Chan, Wai Kit, Daw, Michael I, Mason, John O, Price, David J

“…The development of stable specialized cell types in multicellular organisms relies on mechanisms controlling inductive intercellular signals and the competence…”
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Editorial: Developmental genes and molecular approaches: From embryo to human diseases by Spohr, Tania C L S, Mentlein, Rolf, Mason, John O

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Heparan Sulfate Sulfation by Hs2st Restricts Astroglial Precursor Somal Translocation in Developing Mouse Forebrain by a Non-Cell-Autonomous Mechanism by Clegg, James M, Parkin, Hannah M, Mason, John O, Pratt, Thomas

“…Heparan sulfate (HS) is a cell surface and extracellular matrix carbohydrate extensively modified by differential sulfation. HS interacts physically with…”
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Intravitreal Injection of Bevacizumab (Avastin) as Adjunctive Treatment of Proliferative Diabetic Retinopathy by Mason, John O., Nixon, Peter A., White, Milton F.

“…To report the use of intravitreal bevacizumab (Avastin) as an adjunctive treatment for proliferative diabetic retinopathy (PDR). Retrospective case review…”
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Povidone-iodine contact time and lid speculum use during intravitreal injection by Friedman, Duncan A, Mason, 3rd, John O, Emond, Tracy, McGwin, Jr, Gerald

“…To determine the time necessary for 5% povidone-iodine (PI) to cause a significant reduction in colony-forming units and whether a lid speculum increases the…”
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Visual outcomes of macula-involving rhegmatogenous retinal detachment in patients with and without age-related macular degeneration by Paulk, P Barrett, Eloubeidi, Dala, Johnson, Mark, Swain, Thomas, Mason, 3rd, John O, Curcio, Christine A, Crosson, Jason N

“…The prognosis for patients with macula-off rhegmatogenous retinal detachment (RRD) and concomitant age-related macular degeneration (AMD) is not well known…”
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Real-World Outcomes in Patients with Branch Retinal Vein Occlusion- (BRVO-) Related Macular Edema Treated with Anti-VEGF Injections Alone versus Anti-VEGF Injections Combined with Focal Laser by Thomley, Meredith E., Gross, Cole N., Preda-Naumescu, Ana, Chen, Kelly S., Swain, Thomas, Mason III, John O., Crosson, Jason N.

“…The purpose of this study was to assess outcomes in a real-world nonclinical trial setting of antivascular endothelial growth factor (VEGF) injections alone…”
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Fibrocontractive Muller Cell Phenotypes in Proliferative Diabetic Retinopathy by Guidry, Clyde, King, Jeffery L, Mason, John O., III

“…To evaluate Müller cells as a potential source of fibrocontractive cells in proliferative diabetic retinopathy. Temporal changes in glial fibrillary acidic…”
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The transcription factor Foxg1 regulates the competence of telencephalic cells to adopt subpallial fates in mice by Manuel, Martine, Martynoga, Ben, Yu, Tian, West, John D, Mason, John O, Price, David J

“…Foxg1 is required for development of the ventral telencephalon in the embryonic mammalian forebrain. Although one existing hypothesis suggests that failed…”
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Pax6 Lengthens G1 Phase and Decreases Oscillating Cdk6 Levels in Murine Embryonic Cortical Progenitors by Mi, Da, Manuel, Martine, Huang, Yu-Ting, Mason, John O, Price, David J

“…Pax6 is a key regulator of the rates of progenitor cell division in cerebral corticogenesis. Previous work has suggested that this action is mediated at least…”
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Cerebral Cortex Expression of Gli3 Is Required for Normal Development of the Lateral Olfactory Tract by Amaniti, Eleni-Maria, Kelman, Alexandra, Mason, John O, Theil, Thomas

“…Formation of the lateral olfactory tract (LOT) and innervation of the piriform cortex represent fundamental steps to allow the transmission of olfactory…”
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