Search Results - "Mason, Carol A"
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Reconnecting Eye to Brain
Published in The Journal of neuroscience (19-10-2016)“…Although much is known about the regenerative capacity of retinal ganglion cells, very significant barriers remain in our ability to restore visual function…”
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Integrins Establish Dendrite-Substrate Relationships that Promote Dendritic Self-Avoidance and Patterning in Drosophila Sensory Neurons
Published in Neuron (Cambridge, Mass.) (12-01-2012)“…Dendrites achieve characteristic spacing patterns during development to ensure appropriate coverage of territories. Mechanisms of dendrite positioning…”
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3
Comparative strength and dendritic organization of thalamocortical and corticocortical synapses onto excitatory layer 4 neurons
Published in The Journal of neuroscience (14-05-2014)“…Thalamus is a potent driver of cortical activity even though cortical synapses onto excitatory layer 4 neurons outnumber thalamic synapses 10 to 1. Previous in…”
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4
Eye-specific projections of retinogeniculate axons are altered in albino mice
Published in The Journal of neuroscience (04-04-2012)“…The divergence of retinal ganglion cell (RGC) axons into ipsilateral and contralateral projections at the optic chiasm and the subsequent segregation of…”
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Genetic Modulation of BDNF Signaling Affects the Outcome of Axonal Competition In Vivo
Published in Current biology (05-06-2007)“…Activity-dependent competition that operates on branch stability or formation plays a critical role in shaping the pattern and complexity of axonal terminal…”
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Autophagy linked FYVE (Alfy/WDFY3) is required for establishing neuronal connectivity in the mammalian brain
Published in eLife (20-09-2016)“…The regulation of protein degradation is essential for maintaining the appropriate environment to coordinate complex cell signaling events and to promote…”
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7
L-Dopa and the albino riddle: content of L-Dopa in the developing retina of pigmented and albino mice
Published in PloS one (19-03-2013)“…The absence or deficiency of melanin as in albinos, has detrimental effects on retinal development that include aberrant axonal projections from eye to brain…”
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Development of axon-target specificity of ponto-cerebellar afferents
Published in PLoS biology (01-02-2011)“…The function of neuronal networks relies on selective assembly of synaptic connections during development. We examined how synaptic specificity emerges in the…”
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9
Altered axonal targeting and short-term plasticity in the hippocampus of Disc1 mutant mice
Published in Proceedings of the National Academy of Sciences - PNAS (06-12-2011)“…Carefully designed animal models of genetic risk factors are likely to aid our understanding of the pathogenesis of schizophrenia. Here, we study a mouse…”
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10
Cadherins as Matchmakers
Published in Neuron (Cambridge, Mass.) (25-08-2011)“…Cadherins implement afferent-target matching in invertebrates, but proof for this concept in mammalian circuits has remained elusive. Two new studies in this…”
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Ephrin-B2 and EphB1 Mediate Retinal Axon Divergence at the Optic Chiasm
Published in Neuron (Cambridge, Mass.) (11-09-2003)“…In animals with binocular vision, retinal ganglion cell (RGC) axons either cross or avoid the midline at the optic chiasm. Here, we show that ephrin-Bs in the…”
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Zic2 Patterns Binocular Vision by Specifying the Uncrossed Retinal Projection
Published in Cell (05-09-2003)“…During CNS development, combinatorial expression of transcription factors controls neuronal subtype identity and subsequent axonal trajectory. Regulatory genes…”
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Slit1 and Slit2 Cooperate to Prevent Premature Midline Crossing of Retinal Axons in the Mouse Visual System
Published in Neuron (Cambridge, Mass.) (17-01-2002)“…During development, retinal ganglion cell (RGC) axons either cross or avoid the midline at the optic chiasm. In Drosophila, the Slit protein regulates midline…”
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14
A Role for Nr-CAM in the Patterning of Binocular Visual Pathways
Published in Neuron (Cambridge, Mass.) (18-05-2006)“…Retinal ganglion cell (RGC) axons diverge within the optic chiasm to project to opposite sides of the brain. In mouse, contralateral RGCs are distributed…”
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The Retinal Ganglion Cell Repopulation, Stem Cell Transplantation, and Optic Nerve Regeneration Consortium
Published in Ophthalmology science (Online) (01-12-2023)“…The Retinal Ganglion Cell (RGC) Repopulation, Stem Cell Transplantation, and Optic Nerve Regeneration (RReSTORe) consortium was founded in 2021 to help address…”
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The LRR receptor Islr2 is required for retinal axon routing at the vertebrate optic chiasm
Published in Neural development (22-10-2015)“…In the visual system of most binocular vertebrates, the axons of retinal ganglion cells (RGCs) diverge at the diencephalic midline and extend to targets on…”
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Reciprocal actions of ATF5 and Shh in proliferation of cerebellar granule neuron progenitor cells
Published in Developmental neurobiology (Hoboken, N.J.) (01-06-2012)“…Precise regulation of neuroprogenitor cell proliferation and differentiation is required for successful brain development, but the factors that contribute to…”
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Semaphorin-6D and Plexin-A1 Act in a Non-Cell-Autonomous Manner to Position and Target Retinal Ganglion Cell Axons
Published in The Journal of neuroscience (09-08-2023)“…Semaphorins and Plexins form ligand/receptor pairs that are crucial for a wide range of developmental processes from cell proliferation to axon guidance. The…”
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Retinal Ganglion Cell Axon Guidance in the Mouse Optic Chiasm: Expression and Function of Robos and Slits
Published in The Journal of neuroscience (01-07-2000)“…The ventral midline of the nervous system is an important choice point at which growing axons decide whether to cross and project contralaterally or remain on…”
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Eye‐specific segregation and differential fasciculation of developing retinal ganglion cell axons in the mouse visual pathway
Published in Journal of comparative neurology (1911) (01-05-2018)“…Prior to forming and refining synaptic connections, axons of projection neurons navigate long distances to their targets. While much is known about guidance…”
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