Search Results - "Maslov, Leonid N."

Paeonol promotes Opa1-mediated mitochondrial fusion via activating the CK2α-Stat3 pathway in diabetic cardiomyopathy by Liu, Chaoyang, Han, Yuehu, Gu, Xiaoming, Li, Man, Du, Yanyan, Feng, Na, Li, Juan, Zhang, Shumiao, Maslov, Leonid N., Wang, Guoen, Pei, Jianming, Fu, Feng, Ding, Mingge

“…Diabetes disrupts mitochondrial function and often results in diabetic cardiomyopathy (DCM). Paeonol is a bioactive compound that has been reported to have…”
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Ferroptosis, a Regulated Form of Cell Death, as a Target for the Development of Novel Drugs Preventing Ischemia/Reperfusion of Cardiac Injury, Cardiomyopathy and Stress-Induced Cardiac Injury by Ryabov, Vyacheslav V, Maslov, Leonid N, Vyshlov, Evgeniy V, Mukhomedzyanov, Alexander V, Kilin, Mikhail, Gusakova, Svetlana V, Gombozhapova, Alexandra E, Panteleev, Oleg O

“…The hospital mortality in patients with ST-segment elevation myocardial infarction (STEMI) is about 6% and has not decreased in recent years. The leading cause…”
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Reactive Oxygen Species as Intracellular Signaling Molecules in the Cardiovascular System by Krylatov, Andrey V, Maslov, Leonid N, Voronkov, Nikita S, Boshchenko, Alla A, Popov, Sergey V, Gomez, Ludovic, Wang, Hongxin, Jaggi, Amteshwar S, Downey, James M

“…Background: Redox signaling plays an important role in the lives of cells. This signaling not only becomes apparent in pathologies but is also thought to be…”
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Peptides Are Cardioprotective Drugs of the Future: The Receptor and Signaling Mechanisms of the Cardioprotective Effect of Glucagon-like Peptide-1 Receptor Agonists by Boshchenko, Alla A, Maslov, Leonid N, Mukhomedzyanov, Alexander V, Zhuravleva, Olga A, Slidnevskaya, Alisa S, Naryzhnaya, Natalia V, Zinovieva, Arina S, Ilinykh, Philipp A

“…The high mortality rate among patients with acute myocardial infarction (AMI) is one of the main problems of modern cardiology. It is quite obvious that there…”
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Is oxidative stress of adipocytes a cause or a consequence of the metabolic syndrome? by Maslov, Leonid N, Naryzhnaya, Natalia V, Boshchenko, Alla A, Popov, Sergey V, Ivanov, Vladimir V, Oeltgen, Peter R

“…AbstractMetabolic syndrome is accompanied by oxidative stress in animals and humans. The main source of ROS in experimental metabolic syndrome is NADPH oxidase…”
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PGC-1α Participates in the Protective Effect of Chronic Intermittent Hypobaric Hypoxia on Cardiomyocytes by Gu, Shuo, Hua, Hong, Guo, Xinqi, Jia, Zhanfeng, Zhang, Yi, Maslov, Leonid N., Zhang, Xiangjian, Ma, Huijie 

“…Background/Aims: Myocardial ischemia/reperfusion (I/R) or hypoxia/reoxygenation (H/R) injury is always characterized by Ca 2+ overload, energy metabolism…”
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KATP channels are regulators of programmed cell death and targets for the creation of novel drugs against ischemia/reperfusion cardiac injury by Maslov, Leonid N, Popov, Sergey V, Naryzhnaya, Natalia V, Mukhomedzyanov, Alexandr V, Kurbatov, Boris K, Derkachev, Ivan A, Boshchenko, Alla A, Prasad, N Rajendra, Ma, Huijie, Zhang, Yi, Sufianova, Galina Z, Fu, Feng, Jian‐Ming Pei

“…BackgroundThe use of percutaneous coronary intervention (PCI) in patients with ST‐segment elevation myocardial infarction (STEMI) is associated with a…”
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Reperfusion Cardiac Injury: Receptors and the Signaling Mechanisms by Maslov, Leonid N, Popov, Sergey V, Mukhomedzyanov, Alexandr V, Naryzhnaya, Natalia V, Voronkov, Nikita S, Ryabov, Vyacheslav V, Boshchenko, Alla A, Khaliulin, Igor, Prasad, N Rajendra, Fu, Feng, Pei, Jian-Ming, Logvinov, Sergey V, Oeltgen, Peter R

“…It has been documented that Ca2+ overload and increased production of reactive oxygen species play a significant role in reperfusion injury (RI) of…”
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Apelin Is a Prototype of Novel Drugs for the Treatment of Acute Myocardial Infarction and Adverse Myocardial Remodeling by Popov, Sergey V, Maslov, Leonid N, Mukhomedzyanov, Alexandr V, Kurbatov, Boris K, Gorbunov, Alexandr S, Kilin, Michail, Azev, Viacheslav N, Khlestkina, Maria S, Sufianova, Galina Z

“…In-hospital mortality in patients with ST-segment elevation myocardial infarction (STEMI) is 5-6%. Consequently, it is necessary to develop fundamentally novel…”
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Preconditioning or Postconditioning with 8-Br-cAMP-AM Protects the Heart against Regional Ischemia and Reperfusion: A Role for Mitochondrial Permeability Transition by Khaliulin, Igor, Ascione, Raimondo, Maslov, Leonid N, Amal, Haitham, Suleiman, M Saadeh

“…The cAMP analogue 8-Br-cAMP-AM (8-Br) confers marked protection against global ischaemia/reperfusion of isolated perfused heart. We tested the hypothesis that…”
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Takotsubo Syndrome: Clinical Manifestations, Etiology and Pathogenesis by Prokudina, Ekaterina S, Kurbatov, Boris K, Zavadovsky, Konstantin V, Vrublevsky, Alexander V, Naryzhnaya, Natalia V, Lishmanov, Yuri B, Maslov, Leonid N, Oeltgen, Peter R

“…The purpose of the review is the analysis of clinical and experimental data on the etiology and pathogenesis of takotsubo syndrome (TS). TS is characterized by…”
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The Role of Microvascular Obstruction and Intra-Myocardial Hemorrhage in Reperfusion Cardiac Injury. Analysis of Clinical Data by Ryabov, Vyacheslav V, Vyshlov, Evgenii V, Maslov, Leonid N, Naryzhnaya, Natalia V, Mukhomedzyanov, Alexandr V, Boshchenko, Alla A, Derkachev, Ivan A, Kurbatov, Boris K, Krylatov, Andrey V, Gombozhapova, Aleksandra E, Dil, Stanislav V, Samoylova, Julia O, Fu, Feng, Pei, Jian-Ming, Sufianova, Galina Z, Diez, Emiliano R

“…Microvascular obstruction (MVO) of coronary arteries promotes an increase in mortality and major adverse cardiac events in patients with acute myocardial…”
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The Infarct-Reducing Effect of the δ2 Opioid Receptor Agonist Deltorphin II: The Molecular Mechanism by Popov, Sergey V., Mukhomedzyanov, Alexandr V., Maslov, Leonid N., Naryzhnaya, Natalia V., Kurbatov, Boris K., Prasad, N. Rajendra, Singh, Nirmal, Fu, Feng, Azev, Viacheslav N.

“…The search for novel drugs for the treatment of acute myocardial infarction and reperfusion injury of the heart is an urgent aim of modern pharmacology. Opioid…”
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The Signaling Mechanism of Remote Postconditioning of the Heart: Prospects of the Use of Remote Postconditioning for the Treatment of Acute Myocardial Infarction by Ryabov, Vyacheslav V, Vyshlov, Evgenii V, Maslov, Leonid N, Mukhomedzyanov, Alexandr V, Naryzhnaya, Natalia V, Boshchenko, Alla A, Gombozhapova, Aleksandra E, Samoylova, Julia O

“…Acute myocardial infarction (AMI) remains the leading cause of mortality in the world, highlighting an urgent need for the development of novel, more effective…”
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Physiological and Pathological Role of TRPV1, TRPV2 and TRPV4 Channels in Heart by Gorbunov, Alexandr S, Maslov, Leonid N, Jaggi, Amteshwar S, Singh, Nirmal, De Petrocellis, Luciano, Boshchenko, Alla A, Roohbakhsh, Ali, Bezuglov, Vladimir V, Oeltgen, Peter R

“…Transient receptor potential vanilloid channel 2 (TRPV2) is required for normal cardiac contractility. The stimulation of TRPV1 in isolated cardiomyocytes can…”
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Potential Mechanisms for Organoprotective Effects of Exogenous Nitric Oxide in an Experimental Study by Kamenshchikov, Nikolay O, Diakova, Mariia L, Podoksenov, Yuri K, Churilina, Elena A, Rebrova, Tatiana Yu, Akhmedov, Shamil D, Maslov, Leonid N, Mukhomedzyanov, Alexander V, Kim, Elena B, Tokareva, Ekaterina S, Kravchenko, Igor V, Boiko, Alexander M, Kozulin, Maxim S, Kozlov, Boris N

“…Performing cardiac surgery under cardiopulmonary bypass (CPB) and circulatory arrest (CA) provokes the development of complications caused by tissue…”
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The Nephroprotective Effect of Nitric Oxide during Extracorporeal Circulation: An Experimental Study by Kamenshchikov, Nikolay O, Podoksenov, Yuri K, Kozlov, Boris N, Maslov, Leonid N, Mukhomedzyanov, Alexander V, Tyo, Mark A, Boiko, Alexander M, Margolis, Natalya Yu, Boshchenko, Alla A, Serebryakova, Olga N, Dzyuman, Anna N, Shirshin, Alexander S, Buranov, Sergey N, Selemir, Victor D

“…This study aims to determine the effectiveness of administering 80 ppm nitric oxide in reducing kidney injury, mitochondrial dysfunction and regulated cell…”
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δ-Opioid Receptor as a Molecular Target for Increasing Cardiac Resistance to Reperfusion in Drug Development by Naryzhnaya, Natalia V, Mukhomedzyanov, Alexander V, Sirotina, Maria, Maslov, Leonid N, Kurbatov, Boris K, Gorbunov, Alexander S, Kilin, Mikhail, Kan, Artur, Krylatov, Andrey V, Podoksenov, Yuri K, Logvinov, Sergey V

“…An analysis of published data and the results of our own studies reveal that the activation of a peripheral δ -opioid receptor (δ -OR) increases the cardiac…”
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Remote ischemic preconditioning-induced neuroprotection in cerebral ischemia-reperfusion injury: Preclinical evidence and mechanisms by Sharma, Diwakar, Maslov, Leonid N., Singh, Nirmal, Jaggi, Amteshwar Singh

“…Remote ischemic preconditioning (RIPC) is an intrinsic protective phenomenon in which 3 to 4 interspersed cycles of non-fatal regional ischemia followed by…”
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Circulating Microparticles Are Differentially Increased in Lowlanders and Highlanders with High Altitude Induced Pulmonary Hypertension during the Cold Season by Sydykov, Akylbek, Petrovic, Aleksandar, Maripov, Abdirashit M, Gredic, Marija, Bermes, Daniel Gerd, Kushubakova, Nadira, Muratali Uulu, Kubatbek, Pilz, Christina, Cholponbaeva, Meerim, Duishobaev, Melis, Satybaldyev, Samatbek, Satieva, Nurgul, Mamazhakypov, Argen, Sartmyrzaeva, Meerim, Omurzakova, Nazgul, Kerimbekova, Zhainagul, Baktybek, Nursultan, Kulchoroeva, Cholpon, Pak, Oleg, Zhao, Lan, Weissmann, Norbert, Avdeev, Sergey, Maslov, Leonid N, Ghofrani, Hossein Ardeschir, Schermuly, Ralph Theo, Sarybaev, Akpay S, Kosanovic, Djuro

“…The role of microparticles (MPs) and cold in high altitude pulmonary hypertension (HAPH) remains unexplored. We investigated the impact of long-term cold…”
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