Search Results - "Maslov, Dmitry A."

Mutations in Efflux Pump Rv1258c (Tap) Cause Resistance to Pyrazinamide, Isoniazid, and Streptomycin in M. tuberculosis by Liu, Jiayun, Shi, Wanliang, Zhang, Shuo, Hao, Xiaoke, Maslov, Dmitry A, Shur, Kirill V, Bekker, Olga B, Danilenko, Valery N, Zhang, Ying

“…Although drug resistance in is mainly caused by mutations in drug activating enzymes or drug targets, there is increasing interest in the possible role of…”
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Transcriptomic Profile of Mycobacterium smegmatis in Response to an Imidazo[1,2-b][1,2,4,5]tetrazine Reveals Its Possible Impact on Iron Metabolism by Vatlin, Aleksey A., Shitikov, Egor A., Shahbaaz, Mohd, Bespiatykh, Dmitry A., Klimina, Ksenia M., Christoffels, Alan, Danilenko, Valery N., Maslov, Dmitry A.

“…Tuberculosis (TB), caused by the Mycobacterium tuberculosis complex bacteria, is one of the most pressing health problems. The development of new drugs and new…”
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Novel Derivatives of Quinoxaline-2-carboxylic Acid 1,4-Dioxides as Antimycobacterial Agents: Mechanistic Studies and Therapeutic Potential by Frolova, Svetlana G, Vatlin, Aleksey A, Maslov, Dmitry A, Yusuf, Buhari, Buravchenko, Galina I, Bekker, Olga B, Klimina, Ksenia M, Smirnova, Svetlana V, Shnakhova, Lidia M, Malyants, Irina K, Lashkin, Arseniy I, Tian, Xirong, Alam, Md Shah, Zatonsky, George V, Zhang, Tianyu, Shchekotikhin, Andrey E, Danilenko, Valery N

“…The World Health Organization (WHO) reports that tuberculosis (TB) is one of the top 10 leading causes of global mortality. The increasing incidence of…”
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Kanamycin and Ofloxacin Activate the Intrinsic Resistance to Multiple Antibiotics in Mycobacterium smegmatis by Vatlin, Aleksey A, Bekker, Olga B, Shur, Kirill V, Ilyasov, Rustem A, Shatrov, Petr A, Maslov, Dmitry A, Danilenko, Valery N

“…Drug resistance (DR) in is the main problem in fighting tuberculosis (TB). This pathogenic bacterium has several types of DR implementation: acquired and…”
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Investigating the role of MAB_1915 in intrinsic resistance to multiple drugs in Mycobacterium abscessus by Yusuf, Buhari, Wang, Shuai, Alam, Md Shah, Zhang, Jingran, Liu, Zhiyong, Lu, Ziwen, Ding, Jie, Chiwala, Gift, Gao, Yamin, Fang, Cuiting, Khan, Shahzad Akbar, Tian, Xirong, Islam, Md Mahmudul, Hameed, H M Adnan, Maslov, Dmitry A, Zhong, Nanshan, Hu, Jinxing, Zhang, Tianyu

“…The increasing clinical significance of is owed to its innate high-level, broad-spectrum resistance to antibiotics and therefore rapidly evolves as an…”
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Synthesis and Characterization of Novel 2-Acyl-3-trifluoromethylquinoxaline 1,4-Dioxides as Potential Antimicrobial Agents by Buravchenko, Galina I, Maslov, Dmitry A, Alam, Md Shah, Grammatikova, Natalia E, Frolova, Svetlana G, Vatlin, Aleksey A, Tian, Xirong, Ivanov, Ivan V, Bekker, Olga B, Kryakvin, Maxim A, Dontsova, Olga A, Danilenko, Valery N, Zhang, Tianyu, Shchekotikhin, Andrey E

“…The emergence of drug resistance in pathogens leads to a loss of effectiveness of antimicrobials and complicates the treatment of bacterial infections…”
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Repurposing Based Identification of Novel Inhibitors against MmpS5-MmpL5 Efflux Pump of Mycobacterium smegmatis : A Combined In Silico and In Vitro Study by Shahbaaz, Mohd, Maslov, Dmitry A, Vatlin, Aleksey A, Danilenko, Valery N, Grishina, Maria, Christoffels, Alan

“…In the current era of a pandemic, infections of COVID-19 and Tuberculosis (TB) enhance the detrimental effects of both diseases in suffering individuals. The…”
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MmpS5-MmpL5 Transporters Provide Mycobacterium smegmatis Resistance to imidazo[1,2- b ][1,2,4,5]tetrazines by Maslov, Dmitry A, Shur, Kirill V, Vatlin, Aleksey A, Danilenko, Valery N

“…The emergence and spread of drug-resistant strains (including MDR, XDR, and TDR) force scientists worldwide to search for new anti-tuberculosis drugs. We have…”
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Identification of Mutations Conferring Tryptanthrin Resistance to Mycobacterium smegmatis by Frolova, Svetlana G, Klimina, Ksenia M, Kumar, Ravinder, Vatlin, Aleksey A, Salunke, Deepak B, Kendrekar, Pravin, Danilenko, Valery N, Maslov, Dmitry A

“…Tuberculosis (TB), caused by , is a global burden, responsible for over 1 million deaths annually. The emergence and spread of drug-resistant strains (MDR-,…”
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Resistance to pyrazinamide in Russian Mycobacterium tuberculosis isolates: pncA sequencing versus Bactec MGIT 960 by Maslov, Dmitry A, Zaĭchikova, Marina V, Chernousova, Larisa N, Shur, Kirill V, Bekker, Olga B, Smirnova, Tatiana G, Larionova, Elena E, Andreevskaya, Sofya N, Zhang, Ying, Danilenko, Valery N

“…Summary Resistance to pyrazinamide (PZA) may impact clinical outcome of anti-tuberculosis chemotherapy. PZA susceptibility testing using MGIT 960 is not…”
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Arabinosyltransferase C Mediates Multiple Drugs Intrinsic Resistance by Altering Cell Envelope Permeability in Mycobacterium abscessus by Wang, Shuai, Cai, Xiaoyin, Yu, Wei, Zeng, Sheng, Zhang, Jingran, Guo, Lingmin, Gao, Yamin, Lu, Zhili, Hameed, H. M. Adnan, Fang, Cuiting, Tian, Xirong, Yusuf, Buhari, Chhotaray, Chiranjibi, Alam, M. D. Shah, Zhang, Buchang, Ge, Honghua, Maslov, Dmitry A., Cook, Gregory M., Peng, Jiacong, Lin, Yongping, Zhong, Nanshan, Zhang, Guoliang, Zhang, Tianyu

“…Mycobacterium abscessus is an emerging human pathogen leading to significant morbidity and even mortality, intrinsically resistant to almost all the…”
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Transcriptomic dataset of Mycolicibacterium smegmatis exposed to an imidazo[1,2-b][1,2,4,5]tetrazine by Vatlin, Aleksey A., Klimina, Ksenia M., Frolova, Svetlana G., Danilenko, Valery N., Maslov, Dmitry A.

“…Deciphering the mechanism of action of novel anti-tuberculosis compounds is a key step in the drug development process. We have previously described a number…”
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Sterilizing Effects of Novel Regimens Containing TB47, Clofazimine, and Linezolid in a Murine Model of Tuberculosis by Yu, Wei, Yusuf, Buhari, Wang, Shuai, Tian, Xirong, Hameed, H M Adnan, Lu, Zhili, Chiwala, Gift, Alam, Md Shah, Cook, Gregory M, Maslov, Dmitry A, Zhong, Nanshan, Zhang, Tianyu

“…TB47, a new drug candidate targeting QcrB in the electron transport chain, has shown a unique synergistic activity with clofazimine and forms a highly…”
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Transcriptional regulation of drug resistance mechanisms in Salmonella: where we stand and what we need to know by Shaheen, Aqsa, Tariq, Anam, Shehzad, Aamir, Iqbal, Mazhar, Mirza, Osman, Maslov, Dmitry A., Rahman, Moazur

“…Salmonellae have evolved a wide range of molecular mechanisms to neutralize the effect of antibiotics and evade the host immune system response. These…”
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Synthesis and antimycobacterial activity of imidazo[1,2-b][1,2,4,5]tetrazines by Maslov, Dmitry A., Korotina, Anna V., Shur, Kirill V., Vatlin, Alexey A., Bekker, Olga B., Tolshchina, Svetlana G., Ishmetova, Rashida I., Ignatenko, Nina K., Rusinov, Gennady L., Charushin, Valery N., Danilenko, Valery N.

“…Tuberculosis (TB) has recently become the leading killer among infectious diseases. Multidrug and extensively drug-resistant Mycobacterium tuberculosis strains…”
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CRISPR-Cas Systems: Prospects for Use in Medicine by Zaychikova, Marina V., Danilenko, Valery N., Maslov, Dmitry A.

“…CRISPR-Cas systems, widespread in bacteria and archaea, are mainly responsible for adaptive cellular immunity against exogenous DNA (plasmid and phage)…”
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Characterization of Genetic Variants Associated with Rifampicin Resistance Level in Mycobacterium tuberculosis Clinical Isolates Collected in Guangzhou Chest Hospital, China by Hameed, H.M. Adnan, Fang, Cuiting, Liu, Zhiyong, Ju, Yanan, Han, Xingli, Gao, Yamin, Wang, Shuai, Chiwala, Gift, Tan, Yaoju, Guan, Ping, Hu, Jinxing, Xiong, Xiaoli, Peng, Jiacong, Lin, Yongping, Hussain, Muzammal, Zhong, Nanshan, Maslov, Dmitry A, Cook, Gregory M, Liu, Jianxiong, Zhang, Tianyu

“…Objective: Rifampicin (RIF)-resistance, a surrogate marker for multidrug-resistant tuberculosis (TB), is mediated by mutations in the rpoB gene. We aimed to…”
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Draft Genome Sequences of 12 Mycolicibacterium smegmatis Strains Resistant to Imidazo[1,2- b ][1,2,4,5]Tetrazines by Vatlin, Aleksey A, Shur, Kirill V, Danilenko, Valery N, Maslov, Dmitry A

“…Here, we report 12 draft genome sequences of mutant strains resistant to imidazo[1,2- ][1,2,4,5]tetrazines, which are antituberculosis drug candidates. We have…”
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Sequencing and Analysis of Three Mycobacterium tuberculosis Genomes of the B0/N-90 Sublineage by Zakharevich, Natalia V., Zaychikova, Marina V., Shur, Kirill V., Bekker, Olga B., Maslov, Dmitry A., Danilenko, Valery N.

“…We report the draft genome sequences of three Mycobacterium tuberculosis isolates belonging to the B0/N-90 sublineage, EKB34, EKB53, and EKB79. The B0/N-90…”
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Draft Genome Sequences of Mycobacterium tuberculosis Clinical Isolates from the Ural Region of Russia That Carry the pks15/1 Gene by Shur, Kirill V, Zakharevich, Natalia V, Akimova, Natalia I, Yunes, Roman A, Frolova, Svetlana G, Maslov, Dmitry A, Danilenko, Valery N

“…Here, we report the draft genome sequences of 15 isolates of the Beijing-B0/W-148 sublineage that carry a 7-bp insertion within the gene, which leads to the…”
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