Search Results - "Maskey, R"
-
1
Adenosine deaminase activity in type 2 diabetes mellitus: does it have any role?
Published in BMC endocrine disorders (20-08-2018)“…Diabetes mellitus is a group of metabolic disorders of carbohydrate metabolism in which glucose is underused, producing hyperglycemia. Diabetic patients are…”
Get full text
Journal Article -
2
Prevalence of Hypertension, Obesity, Diabetes, and Metabolic Syndrome in Nepal
Published in International Journal of Hypertension (01-01-2011)“…Background. This study was carried out to establish the prevalence of cardiovascular risks such as hypertension, obesity, and diabetes in Eastern Nepal. This…”
Get full text
Journal Article -
3
Inhibition of pathologic immunoglobulin E in food allergy by EBF-2 and active compound berberine associated with immunometabolism regulation
Published in Frontiers in immunology (07-02-2023)“…Food allergy is a significant public health problem with limited treatment options. As Food Allergy Herbal Formula 2 (FAHF-2) showed potential as a food…”
Get full text
Journal Article -
4
Computational analysis to define efficacy & molecular mechanisms of 7, 4'- Dihydroxyflavone on eosinophilic esophagitis: Ex-vivo validation in human esophagus biopsies
Published in Frontiers in immunology (15-12-2022)“…Eosinophilic Esophagitis (EoE) is a chronic condition characterized by eosinophilic inflammation of the esophagus which leads to esophageal dysfunction with…”
Get full text
Journal Article -
5
Glucodynamics and glucocracy in type 2 diabetes mellitus: clinical evidence and practice-based opinion on modern sulfonylurea use, from an International Expert Group (South Asia, Middle East & Africa) via modified Delphi method
Published in Current medical research and opinion (04-03-2021)“…Type 2 diabetes mellitus (T2DM) is a global epidemic. According to international guidelines, the management protocol of T2DM includes lowering of blood…”
Get full text
Journal Article -
6
Cytochrome P450 3A4 suppression by epimedium and active compound kaempferol leads to synergistic anti-inflammatory effect with corticosteroid
Published in Frontiers in pharmacology (30-01-2023)“…Cytochrome P450 (CYP) 3A4 is a major drug metabolizing enzyme for corticosteroids (CS). Epimedium has been used for asthma and variety of inflammatory…”
Get full text
Journal Article -
7
Berberine Inhibits the Inflammatory Response Induced by Staphylococcus aureus Isolated from Atopic Eczema Patients via the TNF-α/Inflammation/RAGE Pathways
Published in Cells (Basel, Switzerland) (01-10-2024)“…Atopic eczema patients exhibit high levels of ( ) skin colonization. can stimulate macrophages and the expression of proinflammatory cytokines. Berberine…”
Get full text
Journal Article -
8
Formononetin isolated from Sophorae flavescentis inhibits B cell-IgE production by regulating ER-stress transcription factor XBP-1
Published in Frontiers in allergy (01-02-2023)“…IgE plays an important pathologic role in most, if not all, allergic conditions. We previously showed that ASHMI (anti-asthma herbal medicine intervention)…”
Get full text
Journal Article -
9
Diabetes Mellitus and the risk of Primary open angle glaucoma
Published in Nepalese journal of ophthalmology (01-01-2017)“…Diabetes mellitus (DM) is one of the risk factors for Primary open angle glaucoma (POAG). Inclusion of DM as a risk factor for POAG is controversial. The…”
Get full text
Journal Article -
10
The Efficacy & Molecular Mechanisms of a Terpenoid Compound Ganoderic Acid C1 on Corticosteroid-Resistant Neutrophilic Airway Inflammation: In vivo and in vitro Validation
Published in Journal of inflammation research (01-01-2024)“…Neutrophil predominant airway inflammation is associated with severe and steroid-resistant asthma clusters. Previously, we reported efficacy of ASHMI, a…”
Get full text
Journal Article -
11
Stiffness Behavior and Shear Effect in Partially Infilled Reinforced Concrete Frames
Published in Journal of earthquake engineering : JEE (19-05-2014)“…The captive column effect is regarded as one of the deficiencies in concrete buildings. During earthquakes, partially infilled frames often get damaged due to…”
Get full text
Journal Article -
12
Quinary prevention in diabetes care: Need for multidisciplinary approach
Published in Clinical epidemiology and global health (01-07-2021)“…Type 2 diabetes mellitus (T2DM) is a global pandemic with increasing prevalence worldwide. Hearsay, or reported speech, is an important contributor to diabetes…”
Get full text
Journal Article -
13
A small molecule compound berberine as an orally active therapeutic candidate against COVID‐19 and SARS: A computational and mechanistic study
Published in The FASEB journal (01-04-2021)“…The novel coronavirus disease, COVID‐19, has grown into a global pandemic and a major public health threat since its breakout in December 2019. To date, no…”
Get full text
Journal Article -
14
A Flavonoid Compound 7, 4 Dihydroxy Flavone as a Potential Therapeutic for the Treatment and Management of EoE
Published in The FASEB journal (01-05-2022)“…Eosinophilic Esophagitis (EoE) is a chronic condition characterized by esophageal dysfunction including dysphagia, abdominal pain and eosinophilic inflammation…”
Get full text
Journal Article -
15
Quinazolin-4-one Derivatives from Streptomyces Isolates
Published in Journal of natural products (Washington, D.C.) (01-07-2004)“…From the ethyl acetate extract of the strain Streptomyces sp. isolate GW23/1540, besides 16 known products, several 1H-quinazolin-4-one derivatives were…”
Get full text
Journal Article -
16
Chinikomycins A and B: isolation, structure elucidation, and biological activity of novel antibiotics from a marine Streptomyces sp. isolate M045
Published in Journal of natural products (Washington, D.C.) (01-03-2005)“…In our screening of marine Streptomycetes for bioactive principles, two novel antitumor antibiotics designated as chinikomycins A (2a) and B (2b) were isolated…”
Get full text
Journal Article -
17
Scenario of mushroom poisoning in a tertiary care hospital
Published in Journal of Nepal Medical Association (01-10-2009)“…Mushroom poisoning is not new to Nepal. Undocumented and unrecorded mushroom poisoning is more common than the published one. We evaluated the pattern and…”
Get full text
Journal Article -
18
Isolation and structure elucidation of Diazaquinomycin C from a terrestrial streptomyces sp. and confirmation of the akashin structure
Published in Natural product research (01-02-2005)“…In the screening of terrestrial Streptomycetes for bioactive components, a new antibiotic designated as diazaquinomycin C (2b) was isolated. The new antibiotic…”
Get full text
Journal Article -
19
Alkaloids from Oriciopsis glaberrima Engl. (Rutaceae)
Published in Phytochemistry (Oxford) (01-03-2006)“…Alkaloid derivatives, oriciacridone A ( 1) and B ( 2), were isolated from the stems bark of Oriciopsis glaberrima Engl., and their structures determined…”
Get full text
Journal Article -
20
Preclinical Models of Atopic Dermatitis Suitable for Mechanistic and Therapeutic Investigations
Published in Journal of inflammation research (01-01-2024)“…Atopic dermatitis (AD) is a complex immune-mediated abnormality of the skin characterized by impaired barrier function, eczematous dermatitis, chronic pruritus…”
Get full text
Journal Article