Search Results - "Masi, Federico de"
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ATAF1 transcription factor directly regulates abscisic acid biosynthetic gene NCED3 in Arabidopsis thaliana
Published in FEBS open bio (01-01-2013)“…ATAF1, an Arabidopsis thaliana NAC transcription factor, plays important roles in plant adaptation to environmental stress and development. To search for ATAF1…”
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2
Systematic discovery of new recognition peptides mediating protein interaction networks
Published in PLoS biology (01-12-2005)“…Many aspects of cell signalling, trafficking, and targeting are governed by interactions between globular protein domains and short peptide segments. These…”
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3
miRandola 2017: a curated knowledge base of non-invasive biomarkers
Published in Nucleic acids research (04-01-2018)“…Abstract miRandola (http://mirandola.iit.cnr.it/) is a database of extracellular non-coding RNAs (ncRNAs) that was initially published in 2012, foreseeing the…”
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4
A DNA-binding-site landscape and regulatory network analysis for NAC transcription factors in Arabidopsis thaliana
Published in Nucleic acids research (08-07-2014)“…Target gene identification for transcription factors is a prerequisite for the systems wide understanding of organismal behaviour. NAM-ATAF1/2-CUC2 (NAC)…”
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5
High-resolution DNA-binding specificity analysis of yeast transcription factors
Published in Genome Research (01-04-2009)“…Transcription factors (TFs) regulate the expression of genes through sequence-specific interactions with DNA-binding sites. However, despite recent progress in…”
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6
High-throughput sequencing enhanced phage display enables the identification of patient-specific epitope motifs in serum
Published in Scientific reports (06-08-2015)“…Phage display is a prominent screening technique with a multitude of applications including therapeutic antibody development and mapping of antigen epitopes…”
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7
Correction to: The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study
Published in Diabetologia (2021)“…Unfortunately, ‘Present address’ was omitted from one of the addresses provided for Mark I. McCarthy (#26)…”
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8
Cross-recognition of a pit viper (Crotalinae) polyspecific antivenom explored through high-density peptide microarray epitope mapping
Published in PLoS neglected tropical diseases (01-07-2017)“…Snakebite antivenom is a 120 years old invention based on polyclonal mixtures of antibodies purified from the blood of hyper-immunized animals. Knowledge on…”
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9
Control of lysosomal biogenesis and Notch-dependent tissue patterning by components of the TFEB-V-ATPase axis in Drosophila melanogaster
Published in Autophagy (01-01-2016)“…In vertebrates, TFEB (transcription factor EB) and MITF (microphthalmia-associated transcription factor) family of basic Helix-Loop-Helix (bHLH) transcription…”
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10
Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism
Published in Proceedings of the National Academy of Sciences - PNAS (23-01-2018)“…Concern has been raised over increased male reproductive disorders in the Western world, and the disruption of male endocrinology has been suggested to play a…”
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Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals
Published in Nature metabolism (2020)“…Circulating proteins are vital in human health and disease and are frequently used as biomarkers for clinical decision-making or as targets for pharmacological…”
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12
Predicting and elucidating the etiology of fatty liver disease: A machine learning modeling and validation study in the IMI DIRECT cohorts
Published in PLoS medicine (19-06-2020)“…Non-alcoholic fatty liver disease (NAFLD) is highly prevalent and causes serious health complications in individuals with and without type 2 diabetes (T2D)…”
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13
Role of human plasma metabolites in prediabetes and type 2 diabetes from the IMI-DIRECT study
Published in Diabetologia (30-09-2024)“…Type 2 diabetes is a chronic condition that is caused by hyperglycaemia. Our aim was to characterise the metabolomics to find their association with the…”
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14
A Multiparameter Network Reveals Extensive Divergence between C. elegans bHLH Transcription Factors
Published in Cell (23-07-2009)“…Differences in expression, protein interactions, and DNA binding of paralogous transcription factors (“TF parameters”) are thought to be important determinants…”
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15
The Association of Cardiometabolic, Diet and Lifestyle Parameters With Plasma Glucagon-like Peptide-1: An IMI DIRECT Study
Published in The journal of clinical endocrinology and metabolism (13-08-2024)“…Abstract Context The role of glucagon-like peptide-1 (GLP-1) in type 2 diabetes (T2D) and obesity is not fully understood. Objective We investigate the…”
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Using protein design algorithms to understand the molecular basis of disease caused by protein-DNA interactions: the Pax6 example
Published in Nucleic acids research (01-11-2010)“…Quite often a single or a combination of protein mutations is linked to specific diseases. However, distinguishing from sequence information which mutations…”
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17
High-throughput immuno-profiling of mamba (Dendroaspis) venom toxin epitopes using high-density peptide microarrays
Published in Scientific reports (08-11-2016)“…Snakebite envenoming is a serious condition requiring medical attention and administration of antivenom. Current antivenoms are antibody preparations obtained…”
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18
Genome-Wide Association Analysis of Pancreatic Beta-Cell Glucose Sensitivity
Published in The journal of clinical endocrinology and metabolism (01-01-2021)“…Abstract Context Pancreatic beta-cell glucose sensitivity is the slope of the plasma glucose-insulin secretion relationship and is a key predictor of…”
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19
Cross-recognition of a pit viper
Published in PLoS neglected tropical diseases (14-07-2017)“…Snakebite antivenom is a 120 years old invention based on polyclonal mixtures of antibodies purified from the blood of hyper-immunized animals. Knowledge on…”
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20
The role of physical activity in metabolic homeostasis before and after the onset of type 2 diabetes: an IMI DIRECT study
Published in Diabetologia (01-04-2020)“…Aims/hypothesis It is well established that physical activity, abdominal ectopic fat and glycaemic regulation are related but the underlying structure of these…”
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