The potential use of bacteria and bacterial derivatives as drug delivery systems for viral infection

Viral infections in humans are responsible for fatalities worldwide and contribute to the incidence of various human ailments. Controllable targeted medicine delivery against many illnesses, including viral infection, may be significantly aided by using bacteria and bacteria-derived products. They m...

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Bibliographic Details
Published in:	Virology journal Vol. 20; no. 1; pp. 222 - 27
Main Authors:	Faghihkhorasani, Amirhosein, Ahmed, Hanan Hassan, Mashool, Noor Muhammad, Alwan, Mariem, Assefi, Marjan, Adab, Aya Hussein, Yasamineh, Saman, Gholizadeh, Omid, Baghani, Moein
Format:	Journal Article
Language:	English
Published:	England BioMed Central Ltd 03-10-2023 BioMed Central BMC
Subjects:	Antigens Antiviral Agents - therapeutic use Bacteria Bacterial derivatives Bacterial infections Biological products COVID-19 Dengue fever Disease transmission Drug delivery Drug delivery system Drug Delivery Systems Drug therapy Drugs E coli Ebola virus Efficiency Epidemics Genetic engineering Health aspects Hepatitis B Hepatitis C HIV Human immunodeficiency virus Human papillomavirus Humans Infections Influenza Influenza vaccines Listeria Middle East respiratory syndrome Papillomavirus infections Pharmaceutical research Proteins Respiratory diseases Review Salmonella SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Synthetic biology Vaccination Vaccine Vaccines Vehicles Viral diseases Viral infection Viral infections Virus diseases Virus Diseases - drug therapy Viruses Iran Bacteria Bacterial derivatives Vaccine Drug delivery system Viral infection
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Summary:	Viral infections in humans are responsible for fatalities worldwide and contribute to the incidence of various human ailments. Controllable targeted medicine delivery against many illnesses, including viral infection, may be significantly aided by using bacteria and bacteria-derived products. They may accumulate in diseased tissues despite physical obstacles, where they can launch antiviral immunity. The ability to genetically and chemically modify them means that vaccinations against viral infections may be manufactured and delivered to affected tissues more safely and effectively. The objective of this study is to provide an overview of the latest advancements in the field of utilizing bacteria and bacterial derivatives as carriers for administering medication to treat viral diseases such as SARS-CoV-2, hepatitis B virus, hepatitis C virus, human immunodeficiency virus, human papillomavirus, influenza, and Ebola virus.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23
ISSN:	1743-422X 1743-422X
DOI:	10.1186/s12985-023-02183-z