Search Results - "Mashhadi Abolghasem Shirazi, Maryam"
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Alum and a TLR7 agonist combined with built-in TLR4 and 5 agonists synergistically enhance immune responses against HPV RG1 epitope
Published in Scientific reports (05-10-2023)“…To relieve the limitations of the human papillomavirus (HPV) vaccines based on L1 capsid protein, vaccine formulations based on RG1 epitope of HPV L2 using…”
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Immunogenicity evaluation of a novel virus-like particle vaccine candidate against SARS-CoV-2 in BALB/c
Published in Pathogens and disease (17-01-2023)“…Abstract The coronavirus disease (COVID-19) pandemic has imposed deployment of an effective vaccine as a worldwide health priority. The new variants of…”
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Evaluation of transduced dendritic cells expressing HIV-1 p24-Nef antigens in HIV-specific cytotoxic T cells induction as a therapeutic candidate vaccine
Published in Virus research (01-06-2021)“…•Lenti virions have been evaluated powerful tools to mature and transduce dendritic cells.•Dendritic cells showed effective antigen carriers which induce both…”
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Co-administration of rotavirus nanospheres VP6 and NSP4 proteins enhanced the anti-NSP4 humoral responses in immunized mice
Published in Microbial pathogenesis (01-02-2022)“…Inconveniences associated with the efficacy and safety of the World Health Organization (WHO) approved/prequalified live attenuated rotavirus (RV) vaccines,…”
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Co-administration of 2'3'-cGAMP STING activator and CpG-C adjuvants with a mutated form of HPV 16 E7 protein leads to tumor growth inhibition in the mouse model
Published in Infectious agents and cancer (26-01-2021)“…Persistent infection with high-risk genotypes of human papillomavirus (HPV) is the leading cause of cervical cancer. The HPV oncoprotein E7 is constitutively…”
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Murine Dendritic Cells for Immunotherapy and Vaccine Development: Generation, Optimization and Transduction
Published in Vaccine research (Tehran. Online) (01-12-2020)“…Introduction: Dendritic cells (DCs) play crucial roles in cellular immunity as the most powerful antigen presenting cells. They have been widely used for…”
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Nanotechnology and nano-sized tools: Newer approaches to circumvent oncolytic adenovirus limitations
Published in Pharmacology & therapeutics (Oxford) (01-04-2024)“…Oncolytic adenoviruses (OAds), engineered Ads preferentially infect and lyse tumor cells, have attracted remarkable attention as immunotherapy weapons for the…”
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Heterologous administration of HPV16 E7 epitope-loaded nanocomplexes inhibits tumor growth in mouse model
Published in International immunopharmacology (01-12-2021)“…•Negatively-charged nanoadjuvants act as carrier for positively-modified epitope.•Loading epitope on nanoadjuvants forms epitope-nanoadjuvant…”
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Immunoinformatics Approach for Designing an HPV Epitope-Based Vaccine Candidate Harboring Built-in Adjuvants
Published in Vaccine research (Tehran. Online) (01-12-2021)Get full text
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