Search Results - "Masferrer, J."

Discovery and development of next generation sGC stimulators with diverse multidimensional pharmacology and broad therapeutic potential by Buys, E.S., Zimmer, D.P., Chickering, J., Graul, R., Chien, Y.T., Profy, A., Hadcock, J.R., Masferrer, J.L., Milne, G.T.

“…Nitric oxide (NO)-sensitive soluble guanylyl cyclase (sGC), an enzyme that catalyzes the conversion of guanosine-5′-triphosphate (GTP) to cyclic…”
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Role of cyclooxygenases in angiogenesis by Leahy, K M, Koki, A T, Masferrer, J L

“…Angiogenesis is the process by which new blood vessels are formed. This process supports normal physiology as well as contributes to progression of disease…”
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COX‐2 is expressed in human pulmonary, colonic, and mammary tumors by Soslow, Robert A., Dannenberg, Andrew J., Rush, Demaretta, Woerner, B. M., Khan, K. Nasir, Masferrer, J., Koki, Alane T.

“…BACKGROUND The cyclooxygenase (COX) enzyme catalyzes the formation of prostaglandins, which can affect cell proliferation and alter the response of the immune…”
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Safety in radiation oncology: transposition of directive 2013/59/EURATOM in the Spanish Radiation Oncology Departments—recommendations for its adequate and effective application by Pardo Masferrer, J., Prieto Martín, C., Ferrer Albiach, C.

“…Introduction The Official Journal of the European Union published on January 17, 2014 the Council Directive 2013/59/EURATOM of December 5, 2013, which…”
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Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors by MASFERRER, J. L, LEAHY, K. M, KOKI, A. T, ZWEIFEL, B. S, SETTLE, S. L, WOERNER, B. M, EDWARDS, D. A, FLICKINGER, A. G, MOORE, R. J, SEIBERT, K

“…We provide evidence that cyclooxygenase (COX)-2-derived prostaglandins contribute to tumor growth by inducing newly formed blood vessels (neoangiogenesis) that…”
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EP-1953: Patient Safety & Quality Control Working Group of the Spanish Society of Radiation Oncology by Pardo-Masferrer, J, Del Cerro-Peñalver, E, Jiménez-Jiménez, E

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Approach to angiogenesis inhibition based on cyclooxygenase-2 by Masferrer, J

“…Two cyclooxygenase (COX) isoforms have been identified: COX-1 and COX-2. COX-1 is the constitutively expressed form of the enzyme and is ubiquitous in its…”
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4-[5-Methyl-3-phenylisoxazol-4-yl]- benzenesulfonamide, Valdecoxib:  A Potent and Selective Inhibitor of COX-2 by Talley, John J, Brown, David L, Carter, Jeffery S, Graneto, Matthew J, Koboldt, Carol M, Masferrer, Jaime L, Perkins, William E, Rogers, Roland S, Shaffer, Alexander F, Zhang, Yan Y, Zweifel, Ben S, Seibert, Karen

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Cyclooxygenase-2 expression is up-regulated in human pancreatic cancer by TUCKER, O. N, DANNENBERG, A. J, FAHEY, T. J, YANG, E. K, FAN ZHANG, LISONG TENG, DALY, J. M, SOSLOW, R. A, MASFERRER, J. L, WOERNER, B. M, KOKI, A. T

“…A large body of evidence suggests that cyclooxygenase-2 (COX-2) is important in gastrointestinal cancer. The purpose of this study was to determine whether…”
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Pharmacological and Biochemical Demonstration of the Role of Cyclooxygenase 2 in Inflammation and Pain by Seibert, Karen, Zhang, Yan, Leahy, Kathleen, Hauser, Scott, Masferrer, Jaime, Perkins, William, Lee, Len, Isakson, Peter

“…Nonsteroidal antiinflammatory drugs (NSAIDs) are widely used for the treatment of inflammatory diseases, but significant side effects such as gastrointestinal…”
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Preferential enhancement of tumor radioresponse by a cyclooxygenase-2 inhibitor by KISHI, K, PETERSEN, S, PETERSEN, C, HUNTER, N, MASON, K, MASFERRER, J. L, TOFILON, P. J, MILAS, L

“…Cyclooxygenase-2 (COX-2), an inducible isoform of cyclooxygenase, is overexpressed in many types of malignant tumors, where it mediates production of…”
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Polymyositis/dermatomyositis-associated lung disease: analysis of a series of 81 patients by Selva-O’Callaghan, A, Labrador-Horrillo, M, Muñoz-Gall, X, Martínez-Gomez, X, Majó-Masferrer, J, Solans-Laque, R, Simeon-Aznar, C P, Morell-Brotard, F, Vilardell-Tarrés, M

“…The objective of this study was to assess the prevalence, clinical, histological and immunological characteristics, and the long-term outcome of…”
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Influence of frailty on anticoagulant prescription and clinical outcomes after 1-year follow-up in hospitalised older patients with atrial fibrillation by Gullón, Alejandra, Formiga, Francesc, Díez-Manglano, Jesús, Mostaza, José María, Cepeda, José María, Pose, Antonio, Castiella, Jesús, Suárez-Fernández, Carmen

“…Frailty is an important prognostic factor in older adults with cardiovascular diseases. We aim to describe the characteristics of elderly hospitalised frail…”
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Pharmacological Analysis of Cyclooxygenase-1 in Inflammation by Smith, Christopher J., Zhang, Yan, Koboldt, Carol M., Muhammad, Jerry, Zweifel, Ben S., Shaffer, Alex, Talley, John J., Masferrer, Jaime L., Seibert, Karen, Isakson, Peter C.

“…The enzymes cyclooxygenase-1 and cyclooxygenase-2 (COX-1 and COX-2) catalyze the conversion of arachidonic acid to prostaglandin (PG) H2, the precursor of PGs…”
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Inhibitory effects of caffeic acid phenethyl ester on the activity and expression of cyclooxygenase-2 in human oral epithelial cells and in a rat model of inflammation by MICHALUART, P, MASFERRER, J. L, DANNENBERG, A. J, CAROTHERS, A. M, SUBBARAMAIAH, K, ZWEIFEL, B. S, KOBOLDT, C, MESTRE, J. R, GRUNBERGER, D, SACKS, P. G, TANABE, T

“…We investigated the mechanisms by which caffeic acid phenethyl ester (CAPE), a phenolic antioxidant, inhibited the stimulation of prostaglandin (PG) synthesis…”
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Nitric Oxide Activates Cyclooxygenase Enzymes by Salvemini, Daniela, Misko, Thomas P., Masferrer, Jaime L., Seibert, Karen, Currie, Mark G., Needleman, Philip

“…We have evaluated the role of nitric oxide (NO) on the activity of the constitutive and induced forms of cyclooxygenase (COX; COX-1 and COX-2, respectively)…”
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PO-0765: A randomized study with a hyaluronic acid and chondroitin sulfate lotion for radiodermitis in breast cancer patients by Pardo-Masferrer, J, Murcia, M, Soto, R, González, J, Alastuey, I, Montemuiño, S, Ortiz, I, Mena, A

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Enhancement of tumor response to γ-radiation by an inhibitor of cyclooxygenase-2 enzyme by MILAS, L, KISHI, K, HUNTER, N, MASON, K, MASFERRER, J. L, TOFILON, P. J

“…Prostaglandins are involved in the response of tumor and normal tissues to cytotoxic agents such as ionizing radiation. Prostaglandin production is mediated by…”
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Patient safety in radiation oncology in Spain: a need to change by Pardo Masferrer, J., del Cerro Peñalver, E., Contreras Martinez, J., Ferrer Albiach, C.

“…Purpose The Working Group on Patient Safety and Quality of the Spanish Society of Radiation Oncology, revised the most relevant national and international…”
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Prevalence and characterization of breakthrough pain in cancer patients with proctalgia treated with 3D pelvic radiotherapy by Ferrero, V. T., Oset, M. M., Masferrer, J. P., Pardo, E. H., Sorolla, E. J., Largo, S. C.

“…Purpose Radiotherapy-induced dysfunction of the gastrointestinal tract is common in cancer patients and has a significant impact on their quality of life. In…”
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