Search Results - "Maser, Tyler P."

Nrf2-Dependent and -Independent Effects of tert -Butylhydroquinone, CDDO-Im, and H 2 O 2 in Human Jurkat T Cells as Determined by CRISPR/Cas9 Gene Editing by Zagorski, Joseph W, Maser, Tyler P, Liby, Karen T, Rockwell, Cheryl E

“…Nuclear factor erythroid 2-related factor 2 (Nrf2) is a stress-activated transcription factor activated by stimuli such as electrophilic compounds and other…”
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Abstract 3191: The MDM2 inhibitor CGM097 synergizes with the BET inhibitor OTX015 to induce cell death in neuroblastoma cells by Maser, Tyler P., Zagorski, Joseph W., Goodyke, Austin J., VanSickle, Elizabeth A., Bond, Jeffrey P., Sholler, Giselle L. Saulnier

“…Abstract Background: Neuroblastoma (NB) is the most common extracranial solid tumor in infants and children, with amplification of the oncogene MYCN being a…”
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The Nrf2 activators tBHQ and CDDO-Im have both Nrf2-dependent and – independent effects on human Jurkat T cell activation, as determined by CRISPR-Cas9 gene editing by Zagorski, Joseph Ward, Maser, Tyler P, Liby, Karen T, Rockwell, Cheryl Elizabeth

“…Abstract Nuclear factor erythroid 2-related factor 2 (Nrf2) is a stress activated transcription factor, activated by such stimuli as reactive oxygen and…”
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The Nrf2 activator, tBHQ, inhibits IL-2 production by human T cells in a largely Nrf2-independent manner by Zagorski, Joseph Ward, Turley, Alexandra E, Maser, Tyler P, Rockwell, Cheryl Elizabeth

“…Abstract Nrf2 is a transcription factor that is activated by cell stress, such as oxidative insult and exposure to xenobiotics. Upon activation, Nrf2…”
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