Search Results - "Maser, Edmund"

Sex‐specificity in lung cancer risk by Stapelfeld, Claudia, Dammann, Christine, Maser, Edmund

“…Smoking is indisputably linked to lung cancer, yet only a small fraction of smokers develops this disease. Although previously tobacco‐derived carcinogens and…”
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Metabolic activation of 2,4,6-trinitrotoluene; a case for ROS-induced cell damage by Adomako-Bonsu, Amma Gyapomah, Jacobsen, Jana, Maser, Edmund

“…The explosive compound 2,4,6-trinitrotoluene (TNT) is well known as a major component of munitions. In addition to its potential carcinogenicity and…”
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Cytotoxic potency of H2O2 in cell cultures: impact of cell concentration and exposure time by Gülden, Michael, Jess, Anne, Kammann, Julia, Maser, Edmund, Seibert, Hasso

“…Using C6 glioma cells in this study we investigated in detail how exposure time and cell concentration affect the cytotoxic potency of H(2)O(2) in vitro…”
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The hop-derived compounds xanthohumol, isoxanthohumol and 8-prenylnaringenin are tight-binding inhibitors of human aldo-keto reductases 1B1 and 1B10 by Seliger, Jan Moritz, Misuri, Livia, Maser, Edmund, Hintzpeter, Jan

“…Xanthohumol (XN), a prenylated chalcone unique to hops (Humulus lupulus) and two derived prenylflavanones, isoxanthohumol (IX) and 8-prenylnaringenin (8-PN)…”
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Toxicity of functional nano-micro zinc oxide tetrapods: impact of cell culture conditions, cellular age and material properties by Papavlassopoulos, Heike, Mishra, Yogendra K, Kaps, Sören, Paulowicz, Ingo, Abdelaziz, Ramzy, Elbahri, Mady, Maser, Edmund, Adelung, Rainer, Röhl, Claudia

“…With increasing production and applications of nanostructured zinc oxide, e.g., for biomedical and consumer products, the question of safety is getting more…”
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Effects of synthetic gestagens on fish reproduction by Zeilinger, Jana, Steger-Hartmann, Thomas, Maser, Edmund, Goller, Stephan, Vonk, Richardus, Länge, Reinhard

“…Although it is well known that estrogenic steroidal hormones are able to affect the sexual development and reproduction of fish at low concentrations, no data…”
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Dietary Chlorella vulgaris supplementation modulates health, microbiota and the response to oxidative stress of Atlantic salmon by Mueller, Jonas, van Muilekom, Doret R., Ehlers, Jannick, Suhr, Marvin, Hornburg, Stéphanie C., Bang, Corinna, Wilkes, Marie, Schultheiß, Thekla, Maser, Edmund, Rebl, Alexander, Goldammer, Tom, Seibel, Henrike, Schulz, Carsten

“…Microalgae are emerging as functional feed ingredients in aquaculture due to their immune-stimulating and stress-modulating properties. We investigated the…”
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Green tea and one of its constituents, Epigallocatechine-3-gallate, are potent inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 by Hintzpeter, Jan, Stapelfeld, Claudia, Loerz, Christine, Martin, Hans-Joerg, Maser, Edmund

“…The microsomal enzyme 11β-hydroxysteroid deydrogenase type 1 (11β-HSD1) catalyzes the interconversion of glucocorticoid receptor-inert cortisone to receptor-…”
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Critical Role of Monooxygenase in Biodegradation of 2,4,6-Trinitrotoluene by Buttiauxella sp. S19-1 by Xu, Miao, He, Lei, Sun, Ping, Wu, Ming, Cui, Xiyan, Liu, Dong, Adomako-Bonsu, Amma G, Geng, Min, Xiong, Guangming, Guo, Liquan, Maser, Edmund

“…2,4,6-Trinitrotoluene (TNT) is an aromatic pollutant that is difficult to be degraded in the natural environment. The screening of efficient degrading bacteria…”
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Crystal structure and catalytic characterization of the dehydrogenase/reductase SDR family member 4 (DHRS4) from Caenorhabditis elegans by Kisiela, Michael, Faust, Annette, Ebert, Bettina, Maser, Edmund, Scheidig, Axel J.

“…The human dehydrogenase/reductase SDR family member 4 (DHRS4) is a tetrameric protein that is involved in the metabolism of several aromatic carbonyl…”
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Human carbonyl reductases by Malátková, Petra, Maser, Edmund, Wsól, Vladimír

“…Enzymatic carbonyl reduction means the formation of a hydroxy function out of a ketone or aldehyde moiety and applies for the metabolism of physiological…”
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16th Carbonyl Metabolism Meeting: from enzymology to genomics by Maser, Edmund

“…The 16th International Meeting on the Enzymology and Molecular Biology of Carbonyl Metabolism, Castle of Ploen (Schleswig-Holstein, Germany), July 10-15, 2012,…”
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Role of human aldo–keto-reductase AKR1B10 in the protection against toxic aldehydes by Martin, Hans-Jörg, Maser, Edmund

“…Damage of cell membranes by reactive oxygen species results in the formation of toxic lipid peroxides which may ultimately lead to cell death. Among the best…”
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Salinity change evokes stress and immune responses in Atlantic salmon with microalgae showing limited potential for dietary mitigation by van Muilekom, Doret R, Mueller, Jonas, Lindemeyer, Jacqueline, Schultheiß, Thekla, Maser, Edmund, Seibel, Henrike, Rebl, Alexander, Schulz, Carsten, Goldammer, Tom

“…Smoltification was found to impact both immune and stress responses of farmed Atlantic salmon ( ), but little is known about how salinity change affects salmon…”
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Curcumin is a tight-binding inhibitor of the most efficient human daunorubicin reductase – Carbonyl reductase 1 by Hintzpeter, Jan, Hornung, Jan, Ebert, Bettina, Martin, Hans-Jörg, Maser, Edmund

“…Curcumin is a major component of the plant Curcuma longa L. It is traditionally used as a spice and coloring in foods and is an important ingredient in curry…”
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Machine Learning Predicts the Presence of 2,4,6-Trinitrotoluene in Sediments of a Baltic Sea Munitions Dumpsite Using Microbial Community Compositions by Janßen, René, Beck, Aaron J., Werner, Johannes, Dellwig, Olaf, Alneberg, Johannes, Kreikemeyer, Bernd, Maser, Edmund, Böttcher, Claus, Achterberg, Eric P., Andersson, Anders F., Labrenz, Matthias

“…Bacteria are ubiquitous and live in complex microbial communities. Due to differences in physiological properties and niche preferences among community…”
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Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29 by Ebert, Bettina, Kisiela, Michael, Wsól, Vladimir, Maser, Edmund

“…Aldo-keto reductases (AKRs) play central roles in the reductive metabolism of endogenous signaling molecules and in the detoxification of xenobiotics…”
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Reduction of lipid peroxidation products and advanced glycation end‐product precursors by cyanobacterial aldo‐keto reductase AKR3G1—a founding member of the AKR3G subfamily by Hintzpeter, Jan, Martin, Hans‐Joerg, Maser, Edmund

“…The purpose of this study was to investigate the origin and function of the aldo‐keto reductase (AKR) superfamily as enzymes involved in the detoxification of…”
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Degradation of 2,4,6-Trinitrotoluene (TNT): Involvement of Protocatechuate 3,4-Dioxygenase (P34O) in Buttiauxella sp. S19-1 by Xu, Miao, Liu, Dong, Sun, Ping, Li, Yunuo, Wu, Ming, Liu, Wencong, Maser, Edmund, Xiong, Guangming, Guo, Liquan

“…Extensive use and disposal of 2,4,6-trinitrotoluene (TNT), a primary constituent of explosives, pollutes the environment and causes severe damage to human…”
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A Toolbox for the Determination of Nitroaromatic Explosives in Marine Water, Sediment, and Biota Samples on Femtogram Levels by GC-MS/MS by Bünning, Tobias Hartwig, Strehse, Jennifer Susanne, Hollmann, Ann Christin, Bötticher, Tom, Maser, Edmund

“…To determine the amount of the explosives 1,3-dinitrobenzene, 2,4-dinitrotoluene, 2,4,6-trinitrotoluene, and its metabolites in marine samples, a toolbox of…”
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