The in vitro antioxidative activity of some traditional Zulu medicinal plants

Methanol extracts prepared separately from the roots, stems and leaves of four traditional Zulu medicinal plants (Rhoicissus digitata, R. rhomboidea, R. tomentosa and R. tridentata) were tested for their antioxidant activity. The extracts of R. rhomboidea and R. tridentata inhibited the activities o...

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Bibliographic Details
Published in:	Phytotherapy research Vol. 16; no. S1; pp. 51 - 56
Main Authors:	Opoku, A. R., Maseko, N. F., Terblanche, S. E.
Format:	Journal Article
Language:	English
Published:	Chichester, UK John Wiley & Sons, Ltd 01-03-2002 Wiley
Subjects:	Animals antioxidants Antioxidants - pharmacology Biological and medical sciences Free Radical Scavengers - pharmacology free radicals General pharmacology Medical sciences medicinal plants Medicine, African Traditional Microsomes, Liver - drug effects Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phytotherapy Plant Extracts - pharmacology Plant Structures Rats Rats, Wistar Vitaceae Zulu South Africa Africa Rat Pharmacognosy Rodentia Extract Antioxidant In vitro Biological activity Free radical Medicinal plant Vertebrata Mammalia Folk medicine Vitidaceae Dicotyledones Animal Angiospermae Plant origin Spermatophyta
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Summary:	Methanol extracts prepared separately from the roots, stems and leaves of four traditional Zulu medicinal plants (Rhoicissus digitata, R. rhomboidea, R. tomentosa and R. tridentata) were tested for their antioxidant activity. The extracts of R. rhomboidea and R. tridentata inhibited the activities of the 1, 1′‐diphenyl‐2‐picryhydrazyl free radical, xanthine oxidase, and also prevented production of thiobarbituric acid reactive substances and free radical mediated DNA sugar damage. The extracts had a strong chelating effect on Fe2+ ions. R. digitata and R. tomentosa extracts, however, possessed some prooxidative properties at high concentrations. In view of these results, it is apparent that the antioxidative activity of these Zulu medicinal plants plays an important role in the healing of the various diseases that they are used for. Copyright © 2002 John Wiley & Sons, Ltd.
Bibliography:	ark:/67375/WNG-KH8F66RP-V istex:1F011F9E031DFA2D20FA745E5A301F4E3932F0AC Research Committee of the University of Zululand ArticleID:PTR804 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0951-418X 1099-1573
DOI:	10.1002/ptr.804