Search Results - "Masclee, A A"

Effects of Supplementation of the Synbiotic Ecologic® 825/FOS P6 on Intestinal Barrier Function in Healthy Humans: A Randomized Controlled Trial by Wilms, E, Gerritsen, J, Smidt, H, Besseling-van der Vaart, I, Rijkers, G T, Garcia Fuentes, A R, Masclee, A A M, Troost, F J

“…Probiotics, prebiotics and synbiotics have been suggested as dietary strategies to improve intestinal barrier function. This study aimed to assess the effect…”
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Irritable bowel syndrome: methods, mechanisms, and pathophysiology. Methods to assess visceral hypersensitivity in irritable bowel syndrome by Keszthelyi, D, Troost, F J, Masclee, A A

“…Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder, characterized by recurrent abdominal pain or discomfort in combination with…”
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Understanding the role of tryptophan and serotonin metabolism in gastrointestinal function by Keszthelyi, D., Troost, F. J., Masclee, A. A. M.

“…Tryptophan is the precursor of a wide array of metabolites, which are involved in a variety of aspects of human nutrition and metabolism. Accumulating evidence…”
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Impact of commonly used drugs on the composition and metabolic function of the gut microbiota by Vich Vila, Arnau, Collij, Valerie, Sanna, Serena, Sinha, Trishla, Imhann, Floris, Bourgonje, Arno R., Mujagic, Zlatan, Jonkers, Daisy M. A. E., Masclee, Ad A. M., Fu, Jingyuan, Kurilshikov, Alexander, Wijmenga, Cisca, Zhernakova, Alexandra, Weersma, Rinse K.

“…The human gut microbiota has now been associated with drug responses and efficacy, while chemical compounds present in these drugs can also impact the gut…”
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Rome III vs Rome IV criteria for irritable bowel syndrome: A comparison of clinical characteristics in a large cohort study by Vork, L., Weerts, Z. Z. R. M., Mujagic, Z., Kruimel, J. W., Hesselink, M. A. M., Muris, J. W. M., Keszthelyi, D., Jonkers, D. M. A. E., Masclee, A. A. M.

“…Background The Rome criteria for irritable bowel syndrome (IBS) have been revised and are expected to apply only to the subset of Rome III IBS subjects with…”
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Leaky gut and diabetes mellitus: what is the link by de Kort, S, Keszthelyi, D, Masclee, A.A.M

“…Diabetes mellitus is a chronic disease requiring lifelong medical attention. With hundreds of millions suffering worldwide, and a rapidly rising incidence,…”
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Short-chain fatty acids activate AMP-activated protein kinase and ameliorate ethanol-induced intestinal barrier dysfunction in Caco-2 cell monolayers by Elamin, Elhaseen E, Masclee, Ad A, Dekker, Jan, Pieters, Harm-Jan, Jonkers, Daisy M

“…Short-chain fatty acids (SCFAs) have been shown to promote intestinal barrier function, but their protective effects against ethanol-induced intestinal injury…”
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Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases by Sanna, Serena, van Zuydam, Natalie R., Mahajan, Anubha, Kurilshikov, Alexander, Vich Vila, Arnau, Võsa, Urmo, Mujagic, Zlatan, Masclee, Ad A. M., Jonkers, Daisy M. A. E., Oosting, Marije, Joosten, Leo A. B., Netea, Mihai G., Franke, Lude, Zhernakova, Alexandra, Fu, Jingyuan, Wijmenga, Cisca, McCarthy, Mark I.

“…Microbiome-wide association studies on large population cohorts have highlighted associations between the gut microbiome and complex traits, including type 2…”
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High risk of drug‐induced microscopic colitis with concomitant use of NSAIDs and proton pump inhibitors by Verhaegh, B. P. M., Vries, F., Masclee, A. A. M., Keshavarzian, A., Boer, A., Souverein, P. C., Pierik, M. J., Jonkers, D. M. A. E.

“…Summary Background Microscopic colitis (MC) is a chronic bowel disorder characterised by watery diarrhoea. Nonsteroidal anti‐inflammatory drugs (NSAIDs),…”
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The effect of sampling and storage on the fecal microbiota composition in healthy and diseased subjects by Tedjo, Danyta I, Jonkers, Daisy M A E, Savelkoul, Paul H, Masclee, Ad A, van Best, Niels, Pierik, Marieke J, Penders, John

“…Large-scale cohort studies are currently being designed to investigate the human microbiome in health and disease. Adequate sampling strategies are required to…”
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Age-dependent changes in GI physiology and microbiota: time to reconsider? by An, Ran, Wilms, Ellen, Masclee, Ad A M, Smidt, Hauke, Zoetendal, Erwin G, Jonkers, Daisy

“…Our life expectancy is increasing, leading to a rise in the ageing population. Ageing is associated with a decline in physiological function and adaptive…”
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Small intestinal permeability is increased in diarrhoea predominant IBS, while alterations in gastroduodenal permeability in all IBS subtypes are largely attributable to confounders by Mujagic, Z., Ludidi, S., Keszthelyi, D., Hesselink, M. A. M., Kruimel, J. W., Lenaerts, K., Hanssen, N. M. J., Conchillo, J. M., Jonkers, D. M. A. E., Masclee, A. A. M.

“…Summary Background Intestinal permeability has been studied in small groups of IBS patients with contrasting findings. Aims To assess intestinal permeability…”
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Serotonergic reinforcement of intestinal barrier function is impaired in irritable bowel syndrome by Keszthelyi, D., Troost, F. J., Jonkers, D. M., Eijk, H. M., Lindsey, P. J., Dekker, J., Buurman, W. A., Masclee, A. A. M.

“…Summary Background Alterations in serotonergic (5‐HT) metabolism and/or intestinal integrity have been associated with irritable bowel syndrome (IBS). Aims To…”
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Serum I‐FABP as marker for enterocyte damage in coeliac disease and its relation to villous atrophy and circulating autoantibodies by Adriaanse, M. P. M., Tack, G. J., Passos, V. Lima, Damoiseaux, J. G. M. C., Schreurs, M. W. J., Wijck, K., Riedl, R. G., Masclee, A. A. M., Buurman, W. A., Mulder, C. J. J., Vreugdenhil, A. C. E.

“…Summary Background Enterocyte damage is the hallmark of coeliac disease (CD) resulting in malabsorption. Little is known about the recovery of enterocyte…”
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The effect of host genetics on the gut microbiome by Bonder, Marc Jan, Kurilshikov, Alexander, Tigchelaar, Ettje F, Mujagic, Zlatan, Imhann, Floris, Vila, Arnau Vich, Deelen, Patrick, Vatanen, Tommi, Schirmer, Melanie, Smeekens, Sanne P, Zhernakova, Daria V, Jankipersadsing, Soesma A, Jaeger, Martin, Oosting, Marije, Cenit, Maria Carmen, Masclee, Ad A M, Swertz, Morris A, Li, Yang, Kumar, Vinod, Joosten, Leo, Harmsen, Hermie, Weersma, Rinse K, Franke, Lude, Hofker, Marten H, Xavier, Ramnik J, Jonkers, Daisy, Netea, Mihai G, Wijmenga, Cisca, Fu, Jingyuan, Zhernakova, Alexandra

“…Alexandra Zhernakova, Jingyuan Fu, Cisca Wijmenga and colleagues perform genome-wide association analysis for microbiome characteristics in a cohort with fully…”
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Alterations in serotonin metabolism in the irritable bowel syndrome by Thijssen, A. Y., Mujagic, Z., Jonkers, D. M. A. E., Ludidi, S., Keszthelyi, D., Hesselink, M. A., Clemens, C. H. M., Conchillo, J. M., Kruimel, J. W., Masclee, A. A. M.

“…Summary Background Alterations in serotonin (5‐HT) metabolism have been postulated to play a role in the pathogenesis of irritable bowel syndrome (IBS)…”
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Review article: the association of diet with onset and relapse in patients with inflammatory bowel disease by Spooren, C. E. G. M., Pierik, M. J., Zeegers, M. P., Feskens, E. J. M., Masclee, A. A. M., Jonkers, D. M. A. E.

“…Summary Background The role of diet in inflammatory bowel disease (IBD) is supported by migration studies and increasing incidences in line with…”
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Fecal microbial composition of ulcerative colitis and Crohn's disease patients in remission and subsequent exacerbation by Wills, Edgar S, Jonkers, Daisy M A E, Savelkoul, Paul H, Masclee, Ad A, Pierik, Marieke J, Penders, John

“…Limited studies have examined the intestinal microbiota composition in relation to changes in disease course of IBD over time. We aimed to study prospectively…”
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Ileal brake activation: macronutrient-specific effects on eating behavior? by van Avesaat, M, Troost, F J, Ripken, D, Hendriks, H F, Masclee, A A M

“…Background: Activation of the ileal brake, by infusing lipid directly into the distal part of the small intestine, alters gastrointestinal (GI) motility and…”
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Risk factors of frequent exacerbations in difficult-to-treat asthma by ten Brinke, A, Sterk, P. J, Masclee, A. A. M, Spinhoven, P, Schmidt, J. T, Zwinderman, A. H, Rabe, K. F, Bel, E. H

“…Recurrent exacerbations are a major cause of morbidity and medical expenditure in patients with asthma. Various exogenous and endogenous factors are thought to…”
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