Search Results - "Mascle, Xavier H."

Characterization of a C-Terminal SUMO-Interacting Motif Present in Select PIAS-Family Proteins by Lussier-Price, Mathieu, Mascle, Xavier H., Cappadocia, Laurent, Kamada, Rui, Sakaguchi, Kazuyasu, Wahba, Haytham M., Omichinski, James G.

“…The human PIAS proteins are small ubiquitin-like modifier (SUMO) E3 ligases that participate in important cellular functions. Several of these functions depend…”
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Structural and Functional Characterization of the Phosphorylation-Dependent Interaction between PML and SUMO1 by Cappadocia, Laurent, Mascle, Xavier H., Bourdeau, Véronique, Tremblay-Belzile, Samuel, Chaker-Margot, Malik, Lussier-Price, Mathieu, Wada, Junya, Sakaguchi, Kazuyasu, Aubry, Muriel, Ferbeyre, Gerardo, Omichinski, James G.

“…PML and several other proteins localizing in PML-nuclear bodies (PML-NB) contain phosphoSIMs (SUMO-interacting motifs), and phosphorylation of this motif plays…”
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Identification of a Non-covalent Ternary Complex Formed by PIAS1, SUMO1, and UBC9 Proteins Involved in Transcriptional Regulation by Mascle, Xavier H., Lussier-Price, Mathieu, Cappadocia, Laurent, Estephan, Patricia, Raiola, Luca, Omichinski, James G., Aubry, Muriel

“…Post-translational modifications with ubiquitin-like proteins require three sequentially acting enzymes (E1, E2, and E3) that must unambiguously recognize each…”
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Acetylation of SUMO1 Alters Interactions with the SIMs of PML and Daxx in a Protein-Specific Manner by Mascle, Xavier H., Gagnon, Christina, Wahba, Haytham M., Lussier-Price, Mathieu, Cappadocia, Laurent, Sakaguchi, Kazuyasu, Omichinski, James G.

“…The interactions between SUMO proteins and SUMO-interacting motif (SIM) in nuclear bodies formed by the promyelocytic leukemia (PML) protein (PML-NBs) have…”
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Zinc controls PML nuclear body formation through regulation of a paralog specific auto-inhibition in SUMO1 by Lussier-Price, Mathieu, Wahba, Haytham M, Mascle, Xavier H, Cappadocia, Laurent, Bourdeau, Veronique, Gagnon, Christina, Igelmann, Sebastian, Sakaguchi, Kazuyasu, Ferbeyre, Gerardo, Omichinski, James G

“…Abstract SUMO proteins are important regulators of many key cellular functions in part through their ability to form interactions with other proteins…”
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Differential Roles of PML Isoforms by Nisole, Sébastien, Maroui, Mohamed Ali, Mascle, Xavier H, Aubry, Muriel, Chelbi-Alix, Mounira K

“…The tumor suppressor promyelocytic leukemia (PML) protein is fused to the retinoic acid receptor alpha in patients suffering from acute promyelocytic leukemia…”
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Sumoylation of the Transcriptional Intermediary Factor 1β (TIF1β), the Co-repressor of the KRAB Multifinger Proteins, Is Required for Its Transcriptional Activity and Is Modulated by the KRAB Domain by Mascle, Xavier H., Germain-Desprez, Delphine, Huynh, Phuong, Estephan, Patricia, Aubry, Muriel

“…Small ubiquitin-related modifier (SUMO) has emerged as a key post-translational modulator of protein functions. Here we show that TIF1β, a developmental…”
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Role of SUMO in RNF4-mediated Promyelocytic Leukemia Protein (PML) Degradation: Sumoylation of pml and phospho-switch control of its sumo binding domain dissected in living cells{sbox} by Percherancier, Yann, Germain-Desprez, Delphine, Galisson, Frédéric, Mascle, Xavier H, Dianoux, Laurent, Estephan, Patricia, Chelbi-Alix, Mounira K, Aubry, Muriel

“…Promyelocytic leukemia protein (PML) is a tumor suppressor acting as the organizer of subnuclear structures called PML nuclear bodies (NBs). Both covalent…”
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Role of SUMO in RNF4-mediated Promyelocytic Leukemia Protein (PML) Degradation by Percherancier, Yann, Germain-Desprez, Delphine, Galisson, Frédéric, Mascle, Xavier H., Dianoux, Laurent, Estephan, Patricia, Chelbi-Alix, Mounira K., Aubry, Muriel

“…Promyelocytic leukemia protein (PML) is a tumor suppressor acting as the organizer of subnuclear structures called PML nuclear bodies (NBs). Both covalent…”
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Structural and Functional Characterization of the Phosphorylation-Dependent Interaction between PML and SUMO1 by Cappadocia, Laurent, Mascle, Xavier H., Bourdeau, Véronique, Tremblay-Belzile, Samuel, Chaker-Margot, Malik, Lussier-Price, Mathieu, Wada, Junya, Sakaguchi, Kazuyasu, Aubry, Muriel, Ferbeyre, Gerardo, Omichinski, James G.

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Sumoylation of the transcriptional intermediary factor 1beta (TIF1beta), the Co-repressor of the KRAB Multifinger proteins, is required for its transcriptional activity and is modulated by the KRAB domain by Mascle, Xavier H, Germain-Desprez, Delphine, Huynh, Phuong, Estephan, Patricia, Aubry, Muriel

“…Small ubiquitin-related modifier (SUMO) has emerged as a key post-translational modulator of protein functions. Here we show that TIF1beta, a developmental…”
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Sumoylation of the Transcriptional Intermediary Factor 1β (TIF1β), the Co-repressor of the KRAB Multifinger Proteins, Is Required for Its Transcriptional Activity and Is Modulated by the KRAB Domain by Xavier H. Mascle, Delphine Germain-Desprez, Phuong Huynh, Patricia Estephan, Muriel Aubry

“…Small ubiquitin-related modifier (SUMO) has emerged as a key post-translational modulator of protein functions. Here we show that TIF1β, a developmental…”
Get full text