Search Results - "Masato HIROTA"

Fasting-Refeeding Impacts Immune Cell Dynamics and Mucosal Immune Responses by Nagai, Motoyoshi, Noguchi, Ryotaro, Takahashi, Daisuke, Morikawa, Takayuki, Koshida, Kouhei, Komiyama, Seiga, Ishihara, Narumi, Yamada, Takahiro, Kawamura, Yuki I., Muroi, Kisara, Hattori, Kouya, Kobayashi, Nobuhide, Fujimura, Yumiko, Hirota, Masato, Matsumoto, Ryohtaroh, Aoki, Ryo, Tamura-Nakano, Miwa, Sugiyama, Machiko, Katakai, Tomoya, Sato, Shintaro, Takubo, Keiyo, Dohi, Taeko, Hase, Koji

“…Nutritional status potentially influences immune responses; however, how nutritional signals regulate cellular dynamics and functionality remains obscure…”
Get full text

A partial agonist for retinoid X receptor mitigates experimental colitis by Onuki, Masayoshi, Watanabe, Masaki, Ishihara, Narumi, Suzuki, Koichiro, Takizawa, Kei, Hirota, Masato, Yamada, Takahiro, Egawa, Aiko, Shibahara, Osamu, Nishii, Midori, Fujihara, Michiko, Makishima, Makoto, Takahashi, Daisuke, Furusawa, Yukihiro, Kakuta, Hiroki, Hase, Koji

“…Abstract Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn’s disease, is an intractable disease of the gastrointestinal tract. Multiple…”
Get full text

Therapeutic effect of vitamin D3-containing nanostructured lipid carriers on inflammatory bowel disease by Zai, Khadijah, Hirota, Masato, Yamada, Takahiro, Ishihara, Narumi, Mori, Takeshi, Kishimura, Akihiro, Suzuki, Koichiro, Hase, Koji, Katayama, Yoshiki

“…The active form of vitamin D3, 1,25(OH)2D3 has been found to exert multiple effects on the suppression of progression of inflammatory bowel disease (IBD)…”
Get full text

Mucin O-glycans facilitate symbiosynthesis to maintain gut immune homeostasis by Yamada, Takahiro, Hino, Shingo, Iijima, Hideki, Genda, Tomomi, Aoki, Ryo, Nagata, Ryuji, Han, Kyu-Ho, Hirota, Masato, Kinashi, Yusuke, Oguchi, Hiroyuki, Suda, Wataru, Furusawa, Yukihiro, Fujimura, Yumiko, Kunisawa, Jun, Hattori, Masahira, Fukushima, Michihiro, Morita, Tatsuya, Hase, Koji

“…The dysbiosis of gut microbiota has been implicated in the pathogenesis of inflammatory bowel diseases; however, the underlying mechanisms have not yet been…”
Get full text

Phosphoenolpyruvate regulates the Th17 transcriptional program and inhibits autoimmunity by Huang, Tsung-Yen, Hirota, Masato, Sasaki, Daiki, Kalra, Rajkumar Singh, Chien, Hsiao-Chiao, Tamai, Miho, Sarkar, Shukla, Mi, Yang, Miyagi, Mio, Seto, Yu, Ishikawa, Hiroki

“…Aerobic glycolysis, a metabolic pathway essential for effector T cell survival and proliferation, regulates differentiation of autoimmune T helper (Th) 17…”
Get full text

Effects of Li pre-doping on charge/discharge properties of Si thin flakes as a negative electrode for Li-ion batteries by Okubo, Takashi, Saito, Morihiro, Yodoya, Chihiro, Kamei, Akika, Hirota, Masato, Takenaka, Toshio, Okumura, Toyoki, Tasaka, Akimasa, Inaba, Minoru

“…To compensate the large irreversible capacity (Qirr), lithium was pre-doped to Si thin flakes (Si Leaf Powder® (Si-LP), thickness: 100nm) for different times,…”
Get full text

Intestinal Epithelial Cell-specific Deletion of α-Mannosidase II Ameliorates Experimental Colitis by Suzuki, Koichiro, Yamada, Takahiro, Yamazaki, Keiko, Hirota, Masato, Ishihara, Narumi, Sakamoto, Mizuki, Takahashi, Daisuke, Iijima, Hideki, Hase, Koji

“…Inflammatory bowel disease (IBD) is a refractory disease of the gastrointestinal tract that is believed to develop in genetically susceptible individuals…”
Get full text

Human immune and gut microbial parameters associated with inter-individual variations in COVID-19 mRNA vaccine-induced immunity by Hirota, Masato, Tamai, Miho, Yukawa, Sachie, Taira, Naoyuki, Matthews, Melissa M., Toma, Takeshi, Seto, Yu, Yoshida, Makiko, Toguchi, Sakura, Miyagi, Mio, Mori, Tomoari, Tomori, Hiroaki, Tamai, Osamu, Kina, Mitsuo, Sakihara, Eishin, Yamashiro, Chiaki, Miyagi, Masatake, Tamaki, Kentaro, Wolf, Matthias, Collins, Mary K., Kitano, Hiroaki, Ishikawa, Hiroki

“…COVID-19 mRNA vaccines induce protective adaptive immunity against SARS-CoV-2 in most individuals, but there is wide variation in levels of vaccine-induced…”
Get full text

Influence of Li diffusion distance on the negative electrode properties of Si thin flakes for Li secondary batteries by Saito, Morihiro, Yamada, Tomoyuki, Yodoya, Chihiro, Kamei, Akika, Hirota, Masato, Takenaka, Toshio, Tasaka, Akimasa, Inaba, Minoru

“…Pure Si thin flakes (Si Leaf Powder® (Si-LP)) of different thicknesses (50, 100, 200, 300 and 400nm) were prepared, and their charge/discharge properties were…”
Get full text

Experimental study on onset turbulence in a flat-plate boundary layer by Kensuke OKADA, Masato HIROTA, Seiichiro IZAWA, Yu FUKUNISHI

“…A wind tunnel experiment was performed to investigate the suitable conditions in which a localized turbulent region can easily be generated in a flat-plate…”
Get full text

JunB is required for CD8+ T cell responses to acute infections by Sarkar, Shukla, Taira, Naoyuki, Hsieh, Tsung-Han, Chien, Hsiao-Chiao, Hirota, Masato, Koizumi, Shin-Ichi, Sasaki, Daiki, Tamai, Miho, Seto, Yu, Miyagi, Mio, Ishikawa, Hiroki

“…Basic-leucine zipper transcription factor ATF-like (BATF) and interferon regulatory factor 4 (IRF4) are crucial transcription factors for generation of…”
Get full text

Therapeutic effect of vitamin D 3 -containing nanostructured lipid carriers on inflammatory bowel disease by Zai, Khadijah, Hirota, Masato, Yamada, Takahiro, Ishihara, Narumi, Mori, Takeshi, Kishimura, Akihiro, Suzuki, Koichiro, Hase, Koji, Katayama, Yoshiki

“…The active form of vitamin D , 1,25(OH) D has been found to exert multiple effects on the suppression of progression of inflammatory bowel disease (IBD)…”
Get full text

Regulation of inflammatory response of macrophages and induction of regulatory T cells by using retinoic acid-loaded nanostructured lipid carrier by Zai, Khadijah, Ishihara, Narumi, Oguchi, Hiroyuki, Hirota, Masato, Kishimura, Akihiro, Mori, Takeshi, Hase, Koji, Katayama, Yoshiki

“…Immunomodulatory function of all-trans retinoic acid (ATRA) has been gathering much attention for the therapy of autoimmune diseases. ATRA is a chemically…”
Get full text

Intestinal epithelium dysfunctions cause IgA deposition in the kidney glomeruli of intestine-specific Ap1m2-deficient mice by Kinashi, Yusuke, Tanaka, Keisuke, Kimura, Shunsuke, Hirota, Masato, Komiyama, Seiga, Shindo, Tomoko, Hashiguchi, Akinori, Takahashi, Daisuke, Shibata, Shinsuke, Karaki, Shin-Ichiro, Ohno, Hiroshi, Hase, Koji

“…Intestinal epithelial cells (IECs) serve as robust barriers against potentially hostile luminal antigens and commensal microbiota. Epithelial barrier…”
Get full text

Intestinal epithelium dysfunctions cause IgA deposition in the kidney glomeruli of intestine-specific Ap1m2-deficient miceResearch in context by Yusuke Kinashi, Keisuke Tanaka, Shunsuke Kimura, Masato Hirota, Seiga Komiyama, Tomoko Shindo, Akinori Hashiguchi, Daisuke Takahashi, Shinsuke Shibata, Shin-Ichiro Karaki, Hiroshi Ohno, Koji Hase

“…Background: Intestinal epithelial cells (IECs) serve as robust barriers against potentially hostile luminal antigens and commensal microbiota. Epithelial…”
Get full text

Mucin O-glycans facilitate symbiosynthesis to maintain gut immune homeostasisResearch in context by Takahiro Yamada, Shingo Hino, Hideki Iijima, Tomomi Genda, Ryo Aoki, Ryuji Nagata, Kyu-Ho Han, Masato Hirota, Yusuke Kinashi, Hiroyuki Oguchi, Wataru Suda, Yukihiro Furusawa, Yumiko Fujimura, Jun Kunisawa, Masahira Hattori, Michihiro Fukushima, Tatsuya Morita, Koji Hase

“…Background: The dysbiosis of gut microbiota has been implicated in the pathogenesis of inflammatory bowel diseases; however, the underlying mechanisms have not…”
Get full text