Search Results - "Masami, Arai"

The relationship between BRCA-associated breast cancer and age factors: an analysis of the Japanese HBOC consortium database by Okano, Maiko, Nomizu, Tadashi, Tachibana, Kazunoshin, Nagatsuka, Miki, Matsuzaki, Masami, Katagata, Naoto, Ohtake, Toru, Yokoyama, Shiro, Arai, Masami, Nakamura, Seigo

“…BRCA1/2 pathogenic variant prevalence in Japanese breast cancer is unclear. Here, we analyzed BRCA1/2 pathogenic variant prevalence with a particular focus on…”
Get full text

Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2020 for the Clinical Practice of Hereditary Colorectal Cancer by Tomita, Naohiro, Ishida, Hideyuki, Tanakaya, Kohji, Yamaguchi, Tatsuro, Kumamoto, Kensuke, Tanaka, Toshiaki, Hinoi, Takao, Miyakura, Yasuyuki, Hasegawa, Hirotoshi, Takayama, Tetsuji, Ishikawa, Hideki, Nakajima, Takeshi, Chino, Akiko, Shimodaira, Hideki, Hirasawa, Akira, Nakayama, Yoshiko, Sekine, Shigeki, Tamura, Kazuo, Akagi, Kiwamu, Kawasaki, Yuko, Kobayashi, Hirotoshi, Arai, Masami, Itabashi, Michio, Hashiguchi, Yojiro, Sugihara, Kenichi

“…Hereditary colorectal cancer (HCRC) accounts for < 5% of all colorectal cancer cases. Some of the unique characteristics commonly encountered in HCRC cases…”
Get full text

Genetic and clinical characteristics in Japanese hereditary breast and ovarian cancer: first report after establishment of HBOC registration system in Japan by Arai, Masami, Yokoyama, Shiro, Watanabe, Chie, Yoshida, Reiko, Kita, Mizuho, Okawa, Megumi, Sakurai, Akihiro, Sekine, Masayuki, Yotsumoto, Junko, Nomura, Hiroyuki, Akama, Yoshinori, Inuzuka, Mayuko, Nomizu, Tadashi, Enomoto, Takayuki, Nakamura, Seigo

“…The hereditary breast and ovarian cancer (HBOC) registration system of Japan was established by the Japanese HBOC Consortium. The first trial was registered in…”
Get full text

Microsatellite instability and mismatch repair protein expressions in lymphocyte‐predominant breast cancer by Horimoto, Yoshiya, Thinzar Hlaing, May, Saeki, Harumi, Kitano, Shigehisa, Nakai, Katsuya, Sasaki, Ritsuko, Kurisaki‐Arakawa, Aiko, Arakawa, Atsushi, Otsuji, Naomi, Matsuoka, Shuji, Tokuda, Emi, Arai, Masami, Saito, Mitsue

“…The frequency of microsatellite instability (MSI) is reportedly extremely low in breast cancer, despite widespread clinical expectations that many patients…”
Get full text

Recent Advances in the Treatment of Hereditary Breast and Ovarian Cancer in Japan - Elucidation of Clinical and Pathological Characteristics, Establishment of a Nation-wide Registration System, and Improvement of Clinical Practice by ARAI, MASAMI

“…Hereditary breast and ovarian cancer (HBOC) syndrome is defined by pathogenic germline variants of BRCA1 or BRCA2 (BRCA1/2). Genetic testing for BRCA1/2 became…”
Get full text

Brca1L63X/+ rat is a novel model of human BRCA1 deficiency displaying susceptibility to radiation‐induced mammary cancer by Nakamura, Yuzuki, Kubota, Jo, Nishimura, Yukiko, Nagata, Kento, Nishimura, Mayumi, Daino, Kazuhiro, Ishikawa, Atsuko, Kaneko, Takehito, Mashimo, Tomoji, Kokubo, Toshiaki, Takabatake, Masaru, Inoue, Kazumasa, Fukushi, Masahiro, Arai, Masami, Saito, Mitsue, Shimada, Yoshiya, Kakinuma, Shizuko, Imaoka, Tatsuhiko

“…Women who are heterozygous for deleterious BRCA1 germline mutations harbor a high risk of hereditary breast cancer. Previous Brca1‐heterozygous animal models…”
Get full text

The role of functional phosphoric acid ester monomers in the surface treatment of yttria-stabilized tetragonal zirconia polycrystals by ARAI, Masami, TAKAGAKI, Tomohiro, TAKAHASHI, Akifumi, TAGAMI, Junji

“…This study aimed to evaluate the bond strength of a resin cement to yttria-stabilized tetragonal zirconia polycrystals (Y-TZPs) treated with three different…”
Get full text

Involvement of the L-DOPA receptor GPR143 in acute and chronic actions of methylphenidate by Uchimura, Hiraku, Kanai, Kaori, Arai, Masami, Inoue, Miyu, Hishimoto, Akitoyo, Masukawa, Daiki, Goshima, Yoshio

“…Methylphenidate (MPH) and methamphetamine (METH) are the current treatments of choice for attention deficit/hyperactivity disorder. We previously reported that…”
Get full text

Incidence of contralateral and ipsilateral breast cancers and prognosis in BRCA1/2 pathogenic variant carriers based on the Japanese HBOC Consortium registration by Yoshimura, Akiyo, Yokoyama, Shiro, Iwata, Hiroji, Takaiso, Nobue, Nomizu, Tadashi, Arai, Masami, Nakamura, Seigo

“…This study aimed to clarify the breast cancer prognosis in Japanese patients with BRCA1/2 pathogenic variant. We analyzed 2235 women with breast cancer who…”
Get full text

Risk-reducing mastectomy for women with hereditary breast and ovarian cancer (HBOC): analytical results of data from the Japanese Organization of HBOC by Ohsumi, Shozo, Nakamura, Seigo, Miyata, Hiroaki, Watanabe, Chie, Den, Hiroki, Arai, Masami

“…BACKGROUNDRisk-reducing mastectomy is one option for women with hereditary breast and ovarian cancer to reduce the risk of breast cancer. PATIENTS AND…”
Get full text

Coupling between GPR143 and dopamine D2 receptor is required for selective potentiation of dopamine D2 receptor function by L‐3,4‐dihydroxyphenylalanine in the dorsal striatum by Masukawa, Daiki, Kitamura, Satoshi, Tajika, Rei, Uchimura, Hiraku, Arai, Masami, Takada, Yuuki, Arisawa, Tetsu, Otaki, Momoyo, Kanai, Kaori, Kobayashi, Kenta, Miyazaki, Tomoyuki, Goshima, Yoshio

“…Dopamine (DA) is involved in neurological and physiological functions such as motor control. L‐3,4‐dihydroxyphenylalanine (L‐DOPA), a precursor of DA, is…”
Get full text

Correlation between the risk of ovarian cancer and BRCA recurrent pathogenic variants in Japan by Sekine, Masayuki, Enomoto, Takayuki, Arai, Masami, Yokoyama, Shiro, Nomura, Hiroyuki, Nishino, Koji, Ikeuchi, Takeshi, Kuriyama, Yoko, Nakamura, Seigo

“…We previously reported that L63X and Q934X are BRCA1 common founder variants in Japan. So far, there have been no reports of a correlation between such BRCA…”
Get full text

Risk factors for lymph node metastasis of ovarian, fallopian tube and primary peritoneal cancer in hereditary breast and ovarian cancer syndrome by Mitamura, Takashi, Sekine, Masayuki, Arai, Masami, Shibata, Yuka, Kato, Momoko, Yokoyama, Shiro, Yamashita, Hiroko, Watari, Hidemichi, Yabe, Ichiro, Nomura, Hiroyuki, Enomoto, Takayuki, Nakamura, Seigo

“…Abstract Background To establish an individualized surgical strategy for lymphadenectomy in ovarian cancer patients with the germline BRCA1 and BRCA2…”
Get full text

Application of targeted nanopore sequencing for the screening and determination of structural variants in patients with Lynch syndrome by Yamaguchi, Kiyoshi, Kasajima, Rika, Takane, Kiyoko, Hatakeyama, Seira, Shimizu, Eigo, Yamaguchi, Rui, Katayama, Kotoe, Arai, Masami, Ishioka, Chikashi, Iwama, Takeo, Kaneko, Satoshi, Matsubara, Nagahide, Moriya, Yoshihiro, Nomizu, Tadashi, Sugano, Kokichi, Tamura, Kazuo, Tomita, Naohiro, Yoshida, Teruhiko, Sugihara, Kenichi, Nakamura, Yusuke, Miyano, Satoru, Imoto, Seiya, Furukawa, Yoichi, Ikenoue, Tsuneo

“…Lynch syndrome is a hereditary disease characterized by an increased risk of colorectal and other cancers. Germline variants in the mismatch repair (MMR) genes…”
Get full text

Spinal Dural Arteriovenous Fistulas in a Patient with Cowden Syndrome and a Phosphatase and Tensin Homolog Mutation by Fuse, Atsuhito, Fukae, Jiro, Nakjima, Asuka, Mitsuhashi, Takashi, Kurita, Ami, Teranishi, Kohsuke, Arai, Masami, Shimo, Yasushi, Hattori, Nobutaka

“…Cowden syndrome (CS) is an autosomal dominant syndrome characterized by the development of hamartomas and an increased cancer risk. Most CS patients harbor…”
Get full text

Importance of gastric cancer for the diagnosis and surveillance of Japanese Lynch syndrome patients by Ikenoue, Tsuneo, Arai, Masami, Ishioka, Chikashi, Iwama, Takeo, Kaneko, Satoshi, Matsubara, Nagahide, Moriya, Yoshihiro, Nomizu, Tadashi, Sugano, Kokichi, Tamura, Kazuo, Tomita, Naohiro, Yoshida, Teruhiko, Sugihara, Kenichi, Naruse, Hiromu, Yamaguchi, Kiyoshi, Nojima, Masanori, Nakamura, Yusuke, Furukawa, Yoichi

“…Lynch syndrome (LS) is an autosomal dominantly inherited disease predisposed to not only colorectal cancer but also other LS-related tumors. Although the…”
Get full text

Differences in age at diagnosis of ovarian cancer for each BRCA mutation type in Japan: optimal timing to carry out risk-reducing salpingo-oophorectomy by Sekine, Masayuki, Enomoto, Takayuki, Arai, Masami, Den, Hiroki, Nomura, Hiroyuki, Ikeuchi, Takeshi, Nakamura, Seigo

“…and mutation carriers are recommended to undergo risk-reducing salpingo-oophorectomy (RRSO) by age 40 and 45, respectively. However, the carriers have a…”
Get full text

Clinical background and outcomes of risk-reducing salpingo-oophorectomy for hereditary breast and ovarian cancers in Japan by Nomura, Hidetaka, Sekine, Masayuki, Yokoyama, Shiro, Arai, Masami, Enomoto, Takayuki, Takeshima, Nobuhiro, Nakamura, Seigo

“…Background This study aimed to identify the clinical background and treatment outcomes of risk-reducing salpingo-oophorectomy (RRSO) in Japan for women with…”
Get full text

Prognostic Impact of Distribution of Lymph Node Metastases in Stage III Colon Cancer by Nagasaki, Toshiya, Akiyoshi, Takashi, Fujimoto, Yoshiya, Konishi, Tsuyoshi, Nagayama, Satoshi, Fukunaga, Yosuke, Arai, Masami, Ueno, Masashi

“…Background Complete mesocolic excision (CME) with central vascular ligation (CVL) is a well-known concept in colon cancer surgery. However, data on the…”
Get full text

Corrigendum to “Azithromycin induces read-through of the nonsense Apc allele and prevents intestinal tumorigenesis in C3B6F1 ApcMin/+ mice” [Biomed. Pharmacother. 164 (2023) 114968] by Semba, Ryoko, Morioka, Takamitsu, Yanagihara, Hiromi, Suzuki, Kenshi, Tachibana, Hirotaka, Hamoya, Takahiro, Horimoto, Yoshiya, Imaoka, Tatsuhiko, Saito, Mitsue, Kakinuma, Shizuko, Arai, Masami

Get full text