Search Results - "Masalova, O. V."

DEVELOPMENT AND PROPERTIES OF NEUTRALIZING MONOCLONAL ANTIBODIES FOR FUSION PROTEIN OF RESPIRATORY SYNCYTIAL VIRUS by Kushch, A. A., Klimova, R. R., Fedorova, N. E., Masalova, O. V., Niconova, A. A., Lesnova, E. I., Momotyuk, E. D., Demidova, N. A., Samartseva, T. G., Zverev, V. V.

“…Introduction. Respiratory syncytial virus (RSV) is the most common cause of lower respiratory tract infections in infants and the elderly. The absence of a…”
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CHANGE OF PHENOTYPIC PROPERTIES OF ESCAPE MUTANTS AND READAPTANTS OF INFLUENZA VIRUS A (H1N1) PDM09 UNDER THE INFLUENCE OF SELECTED MUTATIONS IN THE MOLECULE OF HEMAGGLUTININ by Timofeeva, T. A., Rudneva, I. A., Shilov, A. A., Balanova, M. A., Artemov, E. K., Kushch, A. A., Masalova, O. V., Klimova, R. R., Grebennikova, T. V., Kaverin, N. V.

“…Introduction. After the emergence and spread of pandemic H1N1 viruses in 2009, antigenic epitopes recognized by neutralizing antibodies against the…”
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Effect of Hepatitis C virus proteins on the production of proinflammatory and profibrotic cytokines in Huh7.5 human hepatoma cells by Masalova, O. V., Lesnova, E. I., Permyakova, K. Yu, Samokhvalov, E. I., Ivanov, A. V., Kochetkov, S. N., Kushch, A. A.

“…Hepatitis C virus (HCV) is a widespread dangerous human pathogen. Up to 80% of HCV-infected individuals develop chronic infection, which is often accompanied…”
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Preventive Vaccination with Mesenchymal Stem Cells Protects Mice from Lethal Infection Caused by Herpes Simplex Virus 1 by Klimova, R. R., Demidova, N. A., Masalova, O. V., Kushch, A. A.

“…Herpes simplex viruses 1 and 2 (HSV-1 and HSV-2) infect almost all organs and tissues, cause genital herpes—the most common sexually transmitted…”
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DNA immunization with a plasmid carrying the gene of hepatitis C virus protein 5A (NS5A) induces an effective cellular immune response by Masalova, O. V, Lesnova, E. I, Grabovetskii, V. V, Smirnova, O. A, Ulanova, T. I, Burkov, A. N, Ivanov, A. V, Zaberezhnyi, A. D, Ataullakhanov, R. I, Kushch, A. A

“…In spite of extensive research, no effective vaccine against hepatitis C virus (HCV) has been developed so far. DNA immunization is a potent technique of…”
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Obtaining and Characterization of the Monoclonal Antibodies Against G-Protein of the Respiratory Syncytial Virus by Demidova, N. A., Klimova, R. R., Kushch, A. A., Lesnova, E. I., Masalova, O. V., Dorofeeva, A. D., Nikonova, A. A., Fedorova, N. E., Zverev, V. V.

“…The aim of this study was to obtain hybridomas producing monoclonal antibodies (Mabs) to the G-protein of the respiratory syncytial virus (RSV), and to…”
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Polyprenyl Phosphates Induce a High Humoral and Cellular Response to Immunization with Recombinant Proteins of the Replicative Complex of the Hepatitis C Virus by Masalova, O. V., Lesnova, E. I., Onishchuk, A. A., Ivanova, A. M., Gerasimova, E. V., Ivanov, A. V., Narovlyansky, A. N., Sanin, A. V., Pronin, A. V., Kushch, A. A.

“…The search for new adjuvants remains the critical task for the creation of hepatitis C vaccines due to the weak immunogenicity of biotechnological products…”
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Low-molecular-weight regulators of biogenic polyamine metabolism affect cytokine production and expression of hepatitis С virus proteins in Huh7.5 human hepatocarcinoma cells by Masalova, O V, Lesnova, E I, Samokhvalov, E I, Permyakova, K Yu, Ivanov, A V, Kochetkov, S N, Kushch, A A

“…Hepatitis C virus (HCV) induces the expression of the genes of proinflammatory cytokines, the excessive production of which may cause cell death, and…”
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COMPARATIVE CHARACTERISTICS OF THE DEVELOPMENT OF INFLUENZA INFECTION IN MACROPHAGES DIFFERENTIATED FROM MONOCYTES OF THP-1 (INFLUENZA A VIRUSES OF SUBTYPES H1, H5 AND H9) by Sokolova, T. M., Poloskov, V. V., Shuvalov, A. N., Rudneva, I. A., Timofeeva, T. A., Klimova, R. R., Masalova, O. V., Kushch, A. A.

“…Macrophages (Mf) play an important role in the pathogenesis of influenza infection, but the obtaining of Mf in large quantities is difficult. In connection…”
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Effect of amino acid substitutions in small subunit of avian H5N2 influenza virus hemagglutinin on selection of the mutants resistant to neutralizing monoclonal antibodies by Ignatieva, A V, Timofeeva, T A, Rudneva, I A, Shilov, A A, Masalova, O V, Klimova, R R, Kushch, A A, Ilyushina, N A, Kaverin, N V

“…Changes associated with the resistance to physical and chemical factors in the hemagglutinin (HA) of influenza A viruses may play an important role in the…”
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Effect of amino acid substitutions in the small subunit of the avian H5N2 influenza virus hemagglutinin on selection of the mutants, resistant to neutralizing monoclonal antibodies by Ignatieva, A. V., Timofeeva, T. A., Rudneva, I. A., Shilov, A. A., Masalova, O. V., Klimova, R. R., Kushch, A. A., Ilyushina, N. A., Kaverin, N. V.

“…Mutations in the hemagglutinin (HA) protein molecule of influenza A viruses associated with the virus’s resistance to physical and chemical factors can play…”
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Enhancement of the immune response by codelivery of hepatitis C virus recombinant DNA and proteins of the replicative complex by Masalova, O. V., Lesnova, E. I., Permyakova, K. Yu, Ivanov, A. V., Tunitskaya, V. L., Kushch, A. A.

“…The plasmids encoding amino acid sequences corresponding to the hepatitis C virus (HCV) are regarded as promising candidates for anti-HCV vaccines. However,…”
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Detection of hepatitis C virus core protein circulating within different virus particle populations by Masalova, O. V., Atanadze, S. N., Samokhvalov, E. I., Petrakova, N. V., Kalinina, T. I., Smirnov, V. D., Khudyakov, Y. E., Fields, H. A., Kushch, A. A.

“…Progress in studying pathogenesis and increasing the reliability of hepatitis C diagnosis can be achieved by analysis of different forms of virus particles…”
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Detection of conservative and variable epitopes of the pandemic influenza virus A(H1N1)pdm09 hemagglutinin using monoclonal antibodies by Masalova, O V, Chichev, E V, Fediakina, I T, Mukasheva, E A, Klimova, R R, Shchelkanov, M Iu, Burtseva, E I, Ivanova, V T, Kushch, A A, L'vov, D K

“…The goal of this work was to analyze the antigenic structure of the hemagglutinin (HA) of the pandemic influenza virus A(H1N1)pdm09 using monoclonal antibodies…”
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Comparative analysis of the immune response to DNA constructions encoding hepatitis C virus nonstructural proteins by Masalova, O V, Lesnova, E I, Ivanov, A V, Pichugin, A V, Permiakova, K Iu, Smirnova, O A, Tynitskaia, V L, Ulanova, T I, Burkov, A N, Kochetkov, S N, Ataullakhanov, R I, Kushch, A A

“…A promising approach to construction of antiviral vaccines consists in activation of cellular immunity with the DNA vaccines. The goal of this work was to…”
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The combined application of nucleotide and amino acid sequences of NS3 hepatitis C virus protein, DNA encoding granulocyte macrophage colony-stimulating factor, and inhibitor of regulatory T cells induces effective immune responce against Hepatitis C virus by Masalova, O. V., Lesnova, E. I., Shingarova, L. N., Tunitskaya, V. L., Ulanova, T. I., Burkov, A. N., Kushch, A. A.

“…Hepatitis C is related to the most important socially significant human infectious diseases. However, there is no vaccine for the hepatitis C virus. The…”
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SOLUBLE FORMS OF MEMBRANOUS ANTIGENS IN SERUM OF PATIENTS WITH HEPATITIS C by Vishnevskaya, T. V., Masalova, O. V., Shkurko, T. V., Evsegneeva, I. V., Ptytzina, Yu. S., Kravchenko, G. A., Rechkina, E. F., Kelly, E. I., Blokhina, N. P., Novikov, V. V., Kushch, A. A.

“…The level of soluble forms (s–forms) of membranous antigenes can reflect the cellular immunity state and play a role of diagnostic and predictive markers in…”
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The combined application of nucleotide and amino acid sequences of NS3 hepatitis C virus protein, DNA encoding granulocyte macrophage colony-stimulating factor and inhibitor of regulatory T cells induces effective immune response against hepatitis C virus by Masalova, O V, Lesnova, E I, Shingarova, L N, Tunitskaia, V L, Ulanova, T I, Burkov, A N, Kushch, A A

“…Hepatitis C is related to the most important socially significant human infectious diseases; however, vaccine against this virus up to now has notbeen created…”
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Development of monoclonal antibodies to highly pathogenic avian influenza H5N1 virus and their application to diagnostics, prophylaxis, and therapy by Masalova, O V, Klimova, R R, Chichev, E V, Fediakina, I T, Loginova, S Y, Borisevich, S V, Bondarev, V P, Deryabin, P G, Lvov, D K, Kushch, A A

“…A panel of 17 monoclonal antibodies (MAbs) against highly pathogenic avian influenza virus (HPAIV) A/Duck/Novosibirsk/56/05 A/H5N1 (subclade 2.2) isolated in…”
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DNA immunization with a plasmid containing gene of hepatitis C virus protein 5A (NS5A) induces the effective cellular immune response by Masalova, O V, Lesnova, E I, Grabovetskiĭ, V V, Smirnova, O A, Ulanova, T I, Burkov, A N, Ivanov, A V, Zaberezhnyĭ, A D, Ataullakhanov, R I, Kushch, A A

“…In spite of extensive research, no effective vaccine against hepatitis C virus (HCV) has been developed so far. DNA immunization is a potent technique of…”
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