Search Results - "Masaeli, Mahdokht"
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Quantitative diagnosis of malignant pleural effusions by single-cell mechanophenotyping
Published in Science translational medicine (20-11-2013)“…Biophysical characteristics of cells are attractive as potential diagnostic markers for cancer. Transformation of cell state or phenotype and the accompanying…”
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Continuous Inertial Focusing and Separation of Particles by Shape
Published in Physical review. X (01-09-2012)“…An effective approach to separating shaped particles is needed to isolate disease-causing cells for diagnostics or to aid in purifying nonspherical particles…”
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Fabrication of three-dimensional porous cell-laden hydrogel for tissue engineering
Published in Biofabrication (01-09-2010)“…For tissue engineering applications, scaffolds should be porous to enable rapid nutrient and oxygen transfer while providing a three-dimensional (3D)…”
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Advances in high-throughput single-cell microtechnologies
Published in Current opinion in biotechnology (01-02-2014)“…Graphical abstract…”
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Interface-Directed Self-Assembly of Cell-Laden Microgels
Published in Small (Weinheim an der Bergstrasse, Germany) (23-04-2010)“…Cell‐laden hydrogels show great promise for creating engineered tissues. However, a major shortcoming with these systems has been the inability to fabricate…”
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Engineering fluid flow using sequenced microstructures
Published in Nature communications (07-05-2013)Get full text
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COSMOS: a platform for real-time morphology-based, label-free cell sorting using deep learning
Published in Communications biology (22-09-2023)“…Cells are the singular building blocks of life, and a comprehensive understanding of morphology, among other properties, is crucial to the assessment of…”
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Author Correction: COSMOS: a platform for real-time morphology-based, label-free cell sorting using deep learning
Published in Communications biology (09-10-2023)Get full text
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Artificial intelligence-driven morphology-based enrichment of malignant cells from body fluid
Published in Modern pathology (01-08-2023)“…Cell morphology is a fundamental feature used to evaluate patient specimens in pathologic analysis. However, traditional cytopathology analysis of patient…”
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Microstructure-induced helical vortices allow single-stream and long-term inertial focusing
Published in Lab on a chip (07-08-2013)“…Fluid inertia has been used to position microparticles in confined channels because it leads to precise and predictable particle migration across streamlines…”
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Engineering fluid flow using sequenced microstructures
Published in Nature communications (01-05-2013)“…Controlling the shape of fluid streams is important across scales: from industrial processing to control of biomolecular interactions. Previous approaches to…”
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Multiparameter mechanical and morphometric screening of cells
Published in Scientific reports (02-12-2016)“…We introduce a label-free method to rapidly phenotype and classify cells purely based on physical properties. We extract 15 biophysical parameters from cells…”
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Research highlights: microfluidics meets big data
Published in Lab on a chip (07-03-2014)“…In this issue we highlight a collection of recent work in which microfluidic parallelization and automation have been employed to address the increasing need…”
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Cell Biophysics for Label-free Single-Cell Analysis and Sorting
Published 01-01-2013“…Recent studies have shown that accurate characterization of biological samples is only possible by analyzing single cells rather than the average response from…”
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Abstract 20983: Size Based Microfluidic Enrichment of Human Inducedpluripotent Cell-derived Cardiomyocytes
Published in Circulation (New York, N.Y.) (11-11-2016)“…While human induced pluripotent stem cell (iPSC)-derived CMs offer a tantalizing cellular model for drug discovery and understanding mechanisms underlying…”
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Abstract 1686: Characterizing tumor heterogeneity through label-free, morphology-based live cell sorting
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract The complexity of cancer is compounded by the continuous emergence of malignant cell populations that drive tumor heterogeneity and challenges…”
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Inertially-induced secondary flow in microchannels
Published 18-10-2011“…We report a novel technique to passively create strong secondary flows at moderate to high flow rates in microchannels, accurately control them and finally,…”
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