Search Results - "Masada, Masahiro"

Effects of Atorvastatin, Amlodipine, and Their Combination on Vascular Dysfunction in Insulin-Resistant Rats by Okamura, Tomio, Tawa, Masashi, Geddawy, Ayman, Shimosato, Takashi, Iwasaki, Hirotaka, Shintaku, Haruo, Yoshida, Yuichi, Masada, Masahiro, Shinozaki, Kazuya, Imamura, Takeshi

“…Deficiency of tetrahydrobiopterin (BH4) in the vascular tissue contributes to endothelial dysfunction through reduced eNOS activity and increased superoxide…”
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Genomic structures of Cyp9m10 in pyrethroid resistant and susceptible strains of Culex quinquefasciatus by Itokawa, Kentaro, Komagata, Osamu, Kasai, Shinji, Okamura, Yoshika, Masada, Masahiro, Tomita, Takashi

“…Development of insecticide resistance reduces the efficacy of controlling measures against the medical and agricultural insect pests. Cytochrome P450s are one…”
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Cis-acting mutation and duplication: History of molecular evolution in a P450 haplotype responsible for insecticide resistance in Culex quinquefasciatus by Itokawa, Kentaro, Komagata, Osamu, Kasai, Shinji, Masada, Masahiro, Tomita, Takashi

“…A cytochrome P450 gene, Cyp9m10, is more than 200-fold overexpressed in a pyrethroid resistant strain of Culex quinquefasciatus, JPal-per. The haplotype of…”
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Overexpression of endothelial nitric oxide synthase accelerates atherosclerotic lesion formation in apoE-deficient mice by Ozaki, Masanori, Kawashima, Seinosuke, Yamashita, Tomoya, Hirase, Tetsuaki, Namiki, Masayuki, Inoue, Nobutaka, Hirata, Ken-ichi, Yasui, Hiroyuki, Sakurai, Hiromu, Yoshida, Yuichi, Masada, Masahiro, Yokoyama, Mitsuhiro

“…Nitric oxide (NO) derived from endothelial NO synthase (eNOS) is regarded as a protective factor against atherosclerosis. Therefore, augmentation of eNOS…”
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Oral Administration of Tetrahydrobiopterin Prevents Endothelial Dysfunction and Vascular Oxidative Stress in the Aortas of Insulin-Resistant Rats by Shinozaki, Kazuya, Nishio, Yoshihiko, Okamura, Tomio, Yoshida, Yuichi, Maegawa, Hiroshi, Kojima, Hideto, Masada, Masahiro, Toda, Noboru, Kikkawa, Ryuichi, Kashiwagi, Atsunori

“…We have reported that a deficiency of tetrahydrobiopterin (BH4), an active cofactor of endothelial NO synthase (eNOS), contributes to the endothelial…”
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Pitavastatin Restores Vascular Dysfunction in Insulin-Resistant State by Inhibiting NAD(P)H Oxidase Activity and Uncoupled Endothelial Nitric Oxide Synthase-Dependent Superoxide Production by Shinozaki, Kazuya, Nishio, Yoshihiko, Ayajiki, Kazuhide, Yoshida, Yuichi, Masada, Masahiro, Kashiwagi, Atsunori, Okamura, Tomio

“…3-Hydroxyl-3-methylglutaryl coenzyme A reductase inhibitors (statins) may benefit the vasculopathy of insulin resistance independent of its lipid-lowering…”
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Stress and Vascular Responses: Oxidative Stress and Endothelial Dysfunction in the Insulin-Resistant State by Shinozaki, Kazuya, Kashiwagi, Atsunori, Masada, Masahiro, Okamura, Tomio

“…Although insulin-resistant states have been associated with endothelial dysfunction due to increased vascular oxidative stress, the underlying mechanisms are…”
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Coronary endothelial dysfunction in the insulin-resistant state is linked to abnormal pteridine metabolism and vascular oxidative stress by Shinozaki, Kazuya, Hirayama, Atsushi, Nishio, Yoshihiko, Yoshida, Yuichi, Ohtani, Tomohito, Okamura, Tomio, Masada, Masahiro, Kikkawa, Ryuichi, Kodama, Kazuhisa, Kashiwagi, Atsunori

“…OBJECTIVES We investigated whether abnormal pteridine metabolism is related to coronary endothelial dysfunction in insulin-resistant subjects. BACKGROUND…”
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Malfunction of Vascular Control in Lifestyle-Related Diseases: Mechanisms Underlying Endothelial Dysfunction in the Insulin-Resistant State by Shinozaki, Kazuya, Ayajiki, Kazuhide, Kashiwagi, Atsunori, Masada, Masahiro, Okamura, Tomio

“…It is tempting to speculate that increased vasoconstriction and loss of endothelium-dependent vasodilation might be etiological factors of elevated blood…”
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Supplement of Tetrahydrobiopterin by a Gene Transfer of GTP Cyclohydrolase I cDNA Improves Vascular Dysfunction in Insulin-Resistant Rats by Shinozaki, Kazuya, Nishio, Yoshihiko, Yoshida, Yuichi, Koya, Daisuke, Ayajiki, Kazuhide, Masada, Masahiro, Kashiwagi, Atsunori, Okamura, Tomio

“…Deficiency of tetrahydrobiopterin (BH4) in the vascular tissue contributes to endothelial dysfunction in the insulin-resistant state. We intended to develop a…”
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Alterations of tetrahydrobiopterin biosynthesis and pteridine levels in mouse tissues during growth and aging by Yoshida, Yu-Ichi, Eda, Setsuko, Masada, Masahiro

“…In the present study, we investigated age-related changes in pteridine levels and enzymatic activity responsible for tetrahydrobiopterin biosynthesis in mouse…”
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Stress and Vascular Responses: Oxidative Stress and Endothelial Dysfunction in the Insulin-Resistant State by Shinozaki, Kazuya, Kashiwagi, Atsunori, Masada, Masahiro, Okamura, Tomio

“…Although insulin-resistant states have been associated with endothelial dysfunction due to increased vascular oxidative stress, the underlying mechanisms are…”
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Tetrahydrobiopterin and Endothelial Dysfunction in Cardiovascular Diseases by Shinozaki Kazuya, Kashiwagi Atsunori, Masada Masahiro, Okamura Tomio

“…Endothelial vasodilator dysfunction is a characteristic feature of patients at risk for coronary atheroscierosis. We have reported that insulin resistance may…”
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Transient assay for in vivo splicing in tobacco leaf cells by particle bombardment by Mitsui, M, Murohashi, Y, Asano, Y, Masada, M, Kodama, H

“…We present a method for detecting spliced products from transiently expressed genes using an intron construct containing the target intron and neighboring…”
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Complexes of serine acetyltransferase and isozymes of cysteine synthase in spinach [Spinacia oleracea] leaves by Zhu, X. (Chiba Univ., Matsudo (Japan). Faculty of Horticulture), Yamaguchi, T, Masada, M

“…Polyclonal antibodies against cysteine synthase (CSase; EC 4.2.99.8) isozymes 1, 2, and 3 were used for the detection of complexes of these isozymes with…”
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Comparative studies on cysteine synthase isozymes from spinach leaves by Yamaguchi, Takayuki, Masada, Masahiro

“…Three types of cysteine synthase (CSase, EC 4.2.99.8) isozymes were purified from spinach leaves. Each isozyme was isolated to homogeneity by preparative PAGE…”
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Purification and characterization of a novel cysteine synthase isozyme from spinach [Spinacia oleracea] hydrated seeds by Yamaguchi, T. (Chiba Univ., Matsudo (Japan). Faculty of Horticulture), Zhu, X, Masada, M

“…A novel type of cysteine synthase (CSase, EC 4.2.99.8) isozyme, designated as CSase 1', was purified to homogeneity from hydrated spinach seeds. The enzyme had…”
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Purification and some properties of GTP cyclohydrolase I from spinach [Spinacia oleracea] leaves by Sohta, Y. (Chiba Univ., Matsudo (Japan). Faculty of Horticulture), Ohta, T, Masada, M

“…GTP cyclohydrolase I (EC 3.5.4.16) has been purified for the first time from a higher plant, spinach leaves. The purified preparation appeared to be…”
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Molecular Mechanisms of Endothelial Dysfunction in the Insulin-Resistant State: the Roles of Abnormal Pteridine Metabolism by Shinozaki Kazuya, Kashiwagi Atsunori, Masada Masahiro, Okamura Tomio

“…Although abnormalities in endothelial function are described in various insulin-resistant conditions, including obesity, diabetes, and hypertension in both…”
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Angiotensin II receptor blockade reduces salt sensitivity of blood pressure through restoration of renal nitric oxide synthesis in patients with diabetic nephropathy by Imanishi, Masahito, Okada, Noriyuki, Konishi, Yoshio, Morikawa, Takashi, Maeda, Isseki, Kitabayashi, Chizuko, Masada, Masahiro, Shirahashi, Nobuo, Wilcox, Christopher S, Nishiyama, Akira

“…Introduction: We have previously demonstrated the increased salt sensitivity of blood pressure (BP) in diabetic patients with early nephropathy. Here, we…”
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