Search Results - "Marzouk, Adel A"

Synthesis, DFT Calculations, Antiproliferative, Bactericidal Activity and Molecular Docking of Novel Mixed-Ligand Salen/8-Hydroxyquinoline Metal Complexes by Al-Farhan, Badriah Saad, Basha, Maram T., Abdel Rahman, Laila H., El-Saghier, Ahmed M. M., Abou El-Ezz, Doaa, Marzouk, Adel A., Shehata, Mohamed R., Abdalla, Ehab M.

“…Despite the common use of salens and hydroxyquinolines as therapeutic and bioactive agents, their metal complexes are still under development. Here, we report…”
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Development and Assessment of 1,5–Diarylpyrazole/Oxime Hybrids Targeting EGFR and JNK–2 as Antiproliferative Agents: A Comprehensive Study through Synthesis, Molecular Docking, and Evaluation by Abdelrahman, Kamal S, Hassan, Heba A, Abdel-Aziz, Salah A, Marzouk, Adel A, Shams, Raef, Osawa, Keima, Abdel-Aziz, Mohamed, Konno, Hiroyuki

“…New 1,5-diarylpyrazole oxime hybrid derivatives (scaffolds A and B) were designed, synthesized, and then their purity was verified using a variety of…”
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Daptomycin: A Novel Macrocyclic Antibiotic as a Chiral Selector in an Organic Polymer Monolithic Capillary for the Enantioselective Analysis of a Set of Pharmaceuticals by Fouad, Ali, Marzouk, Adel A., Shaykoon, Montaser Sh. A., Ibrahim, Samy M., El-Adl, Sobhy M., Ghanem, Ashraf

“…Daptomycin, a macrocyclic antibiotic, is here used as a new chiral selector in preparation of chiral stationary phase (CSP) in a recently prepared polymer…”
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Design, Synthesis, Biological Evaluation, and Computational Studies of Novel Tri-Aryl Imidazole-Benzene Sulfonamide Hybrids as Promising Selective Carbonic Anhydrase IX and XII Inhibitors by Al-Wahaibi, Lamya H., Youssif, Bahaa G. M., Taher, Ehab S., Abdelazeem, Ahmed H., Abdelhamid, Antar A., Marzouk, Adel A.

“…A novel series of tri-aryl imidazole derivatives 5a–n carrying benzene sulfonamide moiety has been designed for their selective inhibitory against hCA IX and…”
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Design, synthesis and antitrypanosomal activity of heteroaryl-based 1,2,4-triazole and 1,3,4-oxadiazole derivatives by Shaykoon, Montaser Sh, Marzouk, Adel A., Soltan, Osama M., Wanas, Amira S., Radwan, Mohamed M., Gouda, Ahmed M., Youssif, Bahaa G.M., Abdel-Aziz, Mohamed

“…[Display omitted] •Two series of 1,2,4-triazole and 1,3,4-oxadiazole derivatives were designed and synthesized.•3a-b and 4a-b showed higher antitrypanosomal…”
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Design, Synthesis, and Antibacterial Screening of Some Novel Heteroaryl-Based Ciprofloxacin Derivatives as DNA Gyrase and Topoisomerase IV Inhibitors by Al-Wahaibi, Lamya H, Amer, Amer A, Marzouk, Adel A, Gomaa, Hesham A M, Youssif, Bahaa G M, Abdelhamid, Antar A

“…A novel series of ciprofloxacin hybrids comprising various heterocycle derivatives has been synthesized and structurally elucidated using H NMR, C NMR, and…”
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Piperidinium Hydrogen Sulfate (PHS) as an Efficient Ionic Liquid Catalyst for the Synthesis of Imidazole Derivative under Solvent‐Free Condition by Albayati, Mustafa R., Marzouk, Adel. A., Abdelhamid, Antar A.

“…Piperidinium hydrogen sulfate is used as a very important new catalyst for the synthesis of the biologically active compounds from a series of…”
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A facile synthesis of 3D NiFe2O4 nanospheres anchored on a novel ionic liquid modified reduced graphene oxide for electrochemical sensing of ledipasvir: Application to human pharmacokinetic study by El-Wekil, Mohamed M., Mahmoud, Ashraf M., Alkahtani, Saad A., Marzouk, Adel A., Ali, Ramadan

“…Novel and sensitive electrochemical sensor was fabricated for the assay of anti-HCV ledipasvir (LEDV) in different matrices. The designed sensor was based on…”
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A Polymer-based Monolithic Capillary Column with Polymyxin-B Chiral Selector for the Enantioselective Nano-High Performance Liquid Chromatographic Pharmaceutical Analysis by Ghanem, Ashraf, Marzouk, Adel A., El-Adl, Sobhy M., Fouad, Ali

“…•A facile one pot synthesis of new Polymyxin-B antibiotic as chiral selector in polymer monolithic•The new capillary columns (150μmID) operate under reversed…”
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Synthesis and characterization of new Cr(III), Fe(III) and Cu(II) complexes incorporating multi-substituted aryl imidazole ligand: Structural, DFT, DNA binding, and biological implications by Abu-Dief, Ahmed M., Abdel-Rahman, Laila H., Abdelhamid, Antar A., Marzouk, Adel A., Shehata, Mohamed R., Bakheet, Mohamed Abdelaal, Almaghrabi, Omar A., Nafady, Ayman

“…Designing new metal-based molecular antibiotics is an efficient approach to overcome the growing threat of antimicrobial resistance. In this paper, novel…”
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Hydrothermal preparation and characterization of ZnFe2O4 magnetic nanoparticles as an efficient heterogeneous catalyst for the synthesis of multi‐substituted imidazoles and study of their anti‐inflammatory activity by Marzouk, Adel A., Abu‐Dief, Ahmed M., Abdelhamid, Antar A.

“…Nanoparticles are key focus of research for a wide range of novel applications. As such, ZnFe2O4 magnetic nanoparticles were synthesized hydrothermally and…”
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Design, synthesis and antiproliferative evaluation of new tricyclic fused thiazolopyrimidines targeting topoisomerase II: Molecular docking and apoptosis inducing activity by Nemr, Mohamed T.M., Sonousi, Amr, Marzouk, Adel A.

“…[Display omitted] •Thiazolopyrimidines derivatives were designed and synthesized as topoisomerase II alpha inhibitors.•Compound 3a was found to be the most…”
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Crystal structure of 1-[2-(4-chloro-phen-yl)-4,5-diphenyl-1 H -imidazol-1-yl]propan-2-ol by Mohamed, Shaaban K, Marzouk, Adel A, Albayati, Mustafa R, Abdelhamid, Antar A, Simpson, Jim

“…The title compound, C H ClN O, crystallizes with two unique mol-ecules in the asymmetric unit. In each mol-ecule, the central imidazole ring is substituted at…”
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Design, Synthesis, Biological Evaluation, and Computational Studies of Novel Fluorinated Candidates as PI3K Inhibitors: Targeting Fluorophilic Binding Sites by Tantawy, Ahmed H, El-Behairy, Mohammed Farrag, Abd-Allah, Walaa Hamada, Jiang, Hong, Wang, Man-Qun, Marzouk, Adel A

“…Highly fluorinated candidates containing anticancer pharmacophores like thiosemicarbazone (5a–e) and its cyclic analogues hydrazineylidenethiazolidine (6a–e),…”
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2-[2-(4-Meth-oxy-phen-yl)-4,5-diphenyl-1H-imidazol-1-yl]ethanol by Mohamed, Shaaban Kamel, Akkurt, Mehmet, Marzouk, Adel A, Abbasov, Vagif M, Gurbanov, Atash V

“…In the title compound, C24H22N2O2, the central imidazole ring makes dihedral angles of 49.45 (8), 88.94 (9) and 19.43 (8)° with the benzene ring and the two…”
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Crystal structure of 1-[2-(2,6-di-chloro-phen-yl)-4,5-diphenyl-1H-imidazol-1-yl]propan-2-ol by Akkurt, Mehmet, Jasinski, Jerry P, Mohamed, Shaaban K, Marzouk, Adel A, Albayati, Mustafa R

“…The central imidazole ring of the title compound, C24H20Cl2N2O, is twisted with respect to with the planes of the 2,6-di-chloro-benzene and two phenyl rings,…”
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Crystal structure of 1-[2-(4-nitro-phen-yl)-4,5-diphenyl-1 H -imidazol-1-yl]propan-2-ol by Simpson, Jim, Mohamed, Shaaban K, Marzouk, Adel A, Abdelhamid, Antar A, Albayati, Mustafa R

“…The title compound, C H N O , crystallizes with two unique but closely r.m.s. overlay fit = 0.215 Å) comparable mol-ecules (1 and 2) in the asymmetric unit of…”
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2-(3,4-Di-meth-oxy-phen-yl)-1-pentyl-4,5-diphenyl-1H-imidazole by Mohamed, Shaaban K, Akkurt, Mehmet, Marzouk, Adel A, Singh, Kuldip, Albayati, Mustafa R

“…The central imidazole ring in the title compound, C28H30N2O2, makes dihedral angles of 28.42 (13), 71.22 (15) and 29.50 (14)°, respectively, with the phenyl…”
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Functionalized polymer monoliths with carbamylated amylose for the enantioselective reversed phase nano-liquid chromatographic separation of a set of racemic pharmaceuticals by Fouad, Ali, Marzouk, Adel A., Ibrahim, Samy M., El-Adl, Sobhy M., Ghanem, Ashraf

“…•The first encapsulation of three carbamylated amylose in organic polymer monolith.•Baseline separation was achieved under rare reversed phase chromatographic…”
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2-(4-Bromo-phen-yl)-1-pentyl-4,5-diphenyl-1H-imidazole by Mohamed, Shaaban K, Akkurt, Mehmet, Singh, Kuldip, Marzouk, Adel A, Albayati, Mustafa R

“…The title compound, C26H25BrN2, is isomorphous with the chloro derivative [2-(4-chloro-phen-yl)-1-pentyl-4,5-diphenyl-1H-imidazole; Mohamed et al. (2013 ▶)…”
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