Search Results - "Maryanski, Janet L"
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EBV infection is common in gingival epithelial cells of the periodontium and worsens during chronic periodontitis
Published in PloS one (19-12-2013)“…An amplifying role for oral epithelial cells (ECs) in Epstein-Barr Virus (EBV) infection has been postulated to explain oral viral shedding. However, while…”
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2
Obligatory Role for Cooperative Signaling by Pre-TCR and Notch during Thymocyte Differentiation
Published in The Journal of immunology (1950) (01-05-2004)“…The first checkpoint during T cell development, known as beta selection, requires the successful rearrangement of the TCR-beta gene locus. Notch signaling has…”
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CD1c-Related DCs that Express CD207/Langerin, but Are Distinguishable from Langerhans Cells, Are Consistently Present in Human Tonsils
Published in Frontiers in immunology (25-05-2016)“…Several subsets of dendritic cells (DCs) are present in the oropharyngeal tonsillar tissues and are thought to behave as major actors in development and…”
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4
Massive clonal expansion of polycytotoxic skin and blood CD8 + T cells in patients with toxic epidermal necrolysis
Published in Science advances (01-03-2021)“…Toxic epidermal necrolysis (TEN) is a life-threatening cutaneous adverse drug reaction. To better understand why skin symptoms are so severe, we conducted a…”
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Comparative T Cell Receptor Repertoire Selection by Antigen after Adoptive Transfer: A Glimpse at an Antigen-Specific Preimmune Repertoire
Published in Proceedings of the National Academy of Sciences - PNAS (18-07-2000)“…The low frequency of precursor cells specific for any particular antigen (Ag) makes it difficult to characterize preimmune T cell receptor (TCR) repertoires…”
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T cell receptor gene rearrangement lineage analysis reveals clues for the origin of highly restricted antigen-specific repertoires
Published in The Journal of experimental medicine (03-03-2003)“…Due to ordered, stage-specific T cell receptor (TCR)-beta and -alpha locus gene rearrangements and cell division during T cell development, a given, ancestral…”
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Memory TCR repertoires analyzed long-term reflect those selected during the primary response
Published in International immunology (01-07-1996)“…Normal T cell repertoire selection and evolution in antigen-specific responses is poorly understood. We have recently described an MHC class I-restricted…”
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Single-Cell PCR Analysis of TCR Repertoires Selected by Antigen In Vivo: A High Magnitude CD8 Response Is Comprised of Very Few Clones
Published in Immunity (Cambridge, Mass.) (01-01-1996)“…Taking advantage of a potent MHC class I–restricted response that allows the identification of antigen- selected CD8 T cells directly ex vivo, we characterized…”
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Cloned cytotoxic T cells recognize an epitope in the circumsporozoite protein and protect against malaria
Published in Nature (London) (28-09-1989)“…Protective immunity against malaria is induced by vaccination of hosts with irradiation-attenuated sporozoites. This immunity is mediated in part by…”
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The Diversity of Antigen-Specific TCR Repertoires Reflects the Relative Complexity of Epitopes Recognized
Published in Human Immunology (01-05-1997)“…Antigen-selected T cell receptor (TCR) repertoires vary in complexity from very limited to extremely diverse. We have previously characterized two different…”
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Book Review Journal Article -
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A Natural Structural Variant of the Mouse TCR beta-Chain Displays Intrinsic Receptor Function and Antigen Specificity
Published in Journal of Immunology (15-12-2006)“…The Cbeta0 alternate cassette exon is located between the Jbeta1 and Cbeta1 genes in the mouse TCR beta-locus. In T cells with a VDJbeta1 rearrangement, the…”
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12
H-2-restricted cytolytic T cells specific for HLA can recognize a synthetic HLA peptide
Published in Nature (London) (11-12-1986)“…It is generally accepted that T lymphocytes recognize antigens in the context of molecules encoded by genes in the major histocompatibility complex (MHC). MHC…”
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A quantitative, single-cell PCR analysis of an antigen-specific TCR repertoire selected during an in vivo CD8 response:: direct evidence for a wide range of clone sizes with uniform tissue distribution
Published in Molecular immunology (01-08-1999)“…The development of T cell effector and memory responses against foreign antigens (Ags) involves the activation, differentiation and proliferation of naive T…”
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14
Specific binding of antigenic peptides to cell-associated MHC class I molecules
Published in Nature (London) (02-05-1991)“…T lymphocytes recognize antigen in the form of peptides that associate with specific alleles of class I or class II major histocompatibility (MHC) molecules…”
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15
Massive clonal expansion of polycytotoxic skin and blood CD8+ T cells in patients with toxic epidermal necrolysis patients
Published in Science advances (19-03-2021)“…This study highlights the key role of polycytotoxic CD8 + T cells in the severity of toxic epidermal necrolysis. Toxic epidermal necrolysis (TEN) is a…”
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16
NMR studies of an oligoproline-containing peptide analog that binds specifically to the H-2Kd histocompatibility molecule
Published in Biochemistry (Easton) (01-10-1991)“…T lymphocytes expressing variable cell surface antigen receptors recognize "processed" forms of antigen, presented on the surface of other cells by molecules…”
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Specificity of peptide presentation by a set of hybrid mouse class I MHC molecules
Published in Nature (London) (17-12-1987)“…The class I molecules of the major histocompatibility complex (H-2 in mouse, HLA in man) are membrane proteins composed of a polymorphic heavy chain associated…”
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EBV Infection Is Common in Gingival Epithelial Cells of the Periodontium and Worsens during Chronic Periodontitis: e80336
Published in PloS one (01-12-2013)“…An amplifying role for oral epithelial cells (ECs) in Epstein-Barr Virus (EBV) infection has been postulated to explain oral viral shedding. However, while…”
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19
T cell receptor genes in a series of class I major histocompatibility complex-restricted cytotoxic T lymphocyte clones specific for a Plasmodium berghei nonapeptide : implications for T cell allelic exclusion and antigen-specific repertoire
Published in The Journal of experimental medicine (01-12-1991)“…We report here the first extensive study of a T cell repertoire for a class I major histocompatibility complex (MHC)-restricted cytotoxic T lymphocyte (CTL)…”
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Multiple T-cell clones specific for the same foreign pMHC ligand can be generated from a single, ancestral TCR-VDJ[beta] precursor
Published in Immunologic research (01-10-2004)“…Owing to ordered, stage-specific T-cell receptor (TCR) gene rearrangements and cell division during T-cell development, small cohorts of "half-sibling" T cells…”
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