Search Results - "Mary E. P. Goad"
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Regulation of Muscle Growth by Multiple Ligands Signaling through Activin Type II Receptors
Published in Proceedings of the National Academy of Sciences - PNAS (13-12-2005)“…Myostatin is a secreted protein that normally functions as a negative regulator of muscle growth. Agents capable of blocking the myostatin signaling pathway…”
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Characterization of the WAVE1 Knock-Out Mouse: Implications for CNS Development
Published in The Journal of neuroscience (15-04-2003)“…Developing neurons must respond to a wide range of extracellular signals during the process of brain morphogenesis. One mechanism through which immature…”
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‘Agricultural’ animals still need a protocol in this case
Published in Lab animal (01-07-2019)Get full text
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The c-Jun NH2-Terminal Kinase Is Essential for Epidermal Growth Factor Expression during Epidermal Morphogenesis
Published in Proceedings of the National Academy of Sciences - PNAS (28-09-2004)“…The c-Jun NH2-terminal kinase (JNK) group of mitogen-activated protein kinases is activated in response to a wide array of cellular stresses and…”
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A high G418-resistant neo(R) transgenic mouse and mouse embryonic fibroblast (MEF) feeder layers for cytotoxicity and gene targeting in vivo and in vitro
Published in Drug and chemical toxicology (New York, N.Y. 1978) (01-10-2011)“…Aminoglycoside antibiotics have been in use since 1944 with the discovery of streptomycin. The aim of this study was to derive a new, highly resistant…”
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Regulation and function of the interleukin 13 receptor alpha 2 during a T helper cell type 2-dominant immune response
Published in The Journal of experimental medicine (17-03-2003)“…Highly polarized type 2 cytokine responses can be harmful and even lethal to the host if they are too vigorous or persist too long. Therefore, it is important…”
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JNK initiates a cytokine cascade that causes Pax2 expression and closure of the optic fissure
Published in Genes & development (15-05-2003)“…The c-Jun NH(2)-terminal kinase (JNK) group of mitogen-activated protein kinases is stimulated in response to a wide array of cellular stresses and…”
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The c-Jun NH 2 -terminal kinase is essential for epidermal growth factor expression during epidermal morphogenesis
Published in Proceedings of the National Academy of Sciences - PNAS (28-09-2004)“…The c-Jun NH 2 -terminal kinase (JNK) group of mitogen-activated protein kinases is activated in response to a wide array of cellular stresses and…”
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Animal Use for In Vitro Work: How Much Justification Is Enough?
Published in Lab animal (01-05-2004)Get full text
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The c-Jun NH sub(2)-terminal kinase is essential for epidermal growth factor expression during epidermal morphogenesis
Published in Proceedings of the National Academy of Sciences - PNAS (28-09-2004)“…The c-Jun NH sub(2)-terminal kinase (JNK) group of mitogen-activated protein kinases is activated in response to a wide array of cellular stresses and…”
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Hepatic toxicity and recovery of Fischer 344 rats following exposure to 2-aminoanthracene by intraperitoneal injection
Published in Toxicologic pathology (2000)Get full text
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Tissue specific toxicities of the anticancer drug 6-thioguanine is dependent on the Hprt status in transgenic mice
Published in The Journal of pharmacology and experimental therapeutics (01-08-1997)“…6-Thioguanine (6TG) a cytostatic antimetabolite is currently used to treat patients with cancer, in particular leukemias. However, one drawback of such use is…”
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Expression of hygR in transgenic mice causes resistance to toxic effects of hygromycin B in vivo
Published in The Journal of pharmacology and experimental therapeutics (01-05-1997)“…Aminoglycoside antibiotics are indispensable for treatment of serious bacterial infections, and despite careful attention to dosage regimens, nephrotoxicity…”
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In Vitro Release of Colchicine Using Poly(phosphazenes): The Development of Delivery Systems for Musculoskeletal Use
Published in Pharmaceutical development and technology (1998)“…ABSTRACT A colchicine release system utilizing biodegradable poly (phosphazenes) was investigated in vitro for intra-articular administration. Polymer…”
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Establishment and validation of an isolated rat lung model for pulmonary metabolism studies
Published in Journal of applied toxicology (01-03-1999)“…An isolated rat lung model was established and validated for use in pulmonary metabolism studies. During the establishment phase of the study, several problems…”
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