Search Results - "Mary, Sophie"
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1
Allosteric modulation of ghrelin receptor signaling by lipids
Published in Nature communications (24-06-2021)“…The membrane is an integral component of the G protein-coupled receptor signaling machinery. Here we demonstrate that lipids regulate the signaling efficacy…”
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2
N‑Terminal Liver-Expressed Antimicrobial Peptide 2 (LEAP2) Region Exhibits Inverse Agonist Activity toward the Ghrelin Receptor
Published in Journal of medicinal chemistry (24-01-2019)“…The ghrelin receptor or growth hormone secretagogue receptor (GHSR) is a G-protein-coupled receptor that controls growth hormone and insulin secretion, food…”
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3
Rosacea is associated with conjoined interactions between physical barrier of the skin and microorganisms: A pilot study
Published in Journal of clinical laboratory analysis (01-09-2020)“…Background Rosacea is a common condition characterized by transient or persistent central facial erythema, and often papules and pustules. Currently, the role…”
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4
Ligands and signaling proteins govern the conformational landscape explored by a G protein-coupled receptor
Published in Proceedings of the National Academy of Sciences - PNAS (22-05-2012)“…The dynamic character of G protein-coupled receptors is essential to their function. However, the details of how ligands stabilize a particular conformation to…”
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5
Concerted conformational dynamics and water movements in the ghrelin G protein-coupled receptor
Published in eLife (03-09-2021)“…There is increasing support for water molecules playing a role in signal propagation through G protein-coupled receptors (GPCRs). However, exploration of the…”
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6
Ghrelin receptor conformational dynamics regulate the transition from a preassembled to an active receptor:Gq complex
Published in Proceedings of the National Academy of Sciences - PNAS (03-02-2015)“…Significance G protein-coupled receptors (GPCRs), one of the largest cell surface receptor families, transmit their signals through the coupling of…”
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7
Amphipol-Assisted in Vitro Folding of G Protein-Coupled Receptors
Published in Biochemistry (Easton) (14-07-2009)“…G protein-coupled receptors (GPCRs) regulate numerous physiological functions. The primary difficulty presented by their study in vitro is to obtain them in…”
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8
Nonionic Homopolymeric Amphipols: Application to Membrane Protein Folding, Cell-Free Synthesis, and Solution Nuclear Magnetic Resonance
Published in Biochemistry (Easton) (21-02-2012)“…Nonionic amphipols (NAPols) synthesized by homotelomerization of an amphiphatic monomer are able to keep membrane proteins (MPs) stable and functional in the…”
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9
Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin
Published in Experimental dermatology (01-11-2008)“…: Skin ageing is a complex process determined by the genetic endowment of individual and environmental factors, such as sun exposure. The effects of skin…”
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10
3T-MRI analysis of epidermis and dermis moisturizing using the T2-mapping sequence
Published in Skin research and technology (01-05-2013)Get more information
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11
Biogenesis of N-cadherin-dependent cell-cell contacts in living fibroblasts is a microtubule-dependent kinesin-driven mechanism
Published in Molecular biology of the cell (01-01-2002)“…Cadherin-mediated cell-cell adhesion is a dynamic process that is regulated during embryonic development, cell migration, and differentiation. Different…”
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12
High Constitutive Activity Is an Intrinsic Feature of Ghrelin Receptor Protein
Published in The Journal of biological chemistry (01-02-2012)“…Despite its central role in signaling and the potential therapeutic applications of inverse agonists, the molecular mechanisms underlying G protein-coupled…”
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13
Exploratory study of the typology of various grades of mature skin
Published in Skin research and technology (01-02-2013)“…Post-menopausal skin aging has intrinsic as well as extrinsic origins, and this process induces important disparities of appearance and feeling within an age…”
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14
Glutathione S-transferase M1 and multidrug resistance protein 1 act in synergy to protect melanoma cells from vincristine effects
Published in Molecular pharmacology (01-04-2004)“…Previous studies have shown that glutathione S-transferases (GSTs) can operate in synergy with efflux transporters, multi-drug resistance proteins (MRPs), to…”
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15
Engineering a G protein‐coupled receptor for structural studies: Stabilization of the BLT1 receptor ground state
Published in Protein science (01-04-2009)“…Structural characterization of membrane proteins is hampered by their instability in detergent solutions. We modified here a G protein‐coupled receptor, the…”
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16
G Protein Activation by the Leukotriene B4 Receptor Dimer
Published in The Journal of biological chemistry (25-07-2008)“…There is compelling evidence that G protein-coupled receptors exist as homo- and heterodimers, but the way these assemblies function at the molecular level…”
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17
Skin radiance: how to quantify? Validation of an optical method
Published in Skin research and technology (01-02-2007)“…The aim of this study was to validate an optic device used to measure the quantity of light reflected by the skin, which depends on the brightness of the skin…”
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18
Cdc42Hs and Rac1 GTPases Induce the Collapse of the Vimentin Intermediate Filament Network
Published in The Journal of biological chemistry (20-10-2000)“…In this study we show that expression of active Cdc42Hs and Rac1 GTPases, two Rho family members, leads to the reorganization of the vimentin intermediate…”
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19
Expression of Central and Peripheral Cannabinoid Receptors in Human Immune Tissues and Leukocyte Subpopulations
Published in European journal of biochemistry (15-08-1995)“…Two proteins with seven transmembrane‐spanning domains typical of guanosine‐nucleotide‐binding‐protein‐coupled receptors have been identified as cannabinoid…”
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20
Age-related changes in skin topography and microcirculation
Published in Archives of Dermatological Research (01-03-2006)“…Skin topography and microvasculature undergo characteristic changes with age. Although several non-invasive bioengineering methods are currently available to…”
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