The triad of Iron deficiency anemia, hepatosplenomegaly and growth retardation with normal serum zinc levels in a 14-year-old boy

The triad of Iron deficiency anemia, hepatosplenomegaly and growth retardation with normal serum zinc levels in a 14-year-old boy

A triad of iron deficiency anemia, hepatosplenomegaly and growth retardation occurring in tandem with zinc deficiency has been reported in the past as components of either Prasad's syndrome or hypopituitarism. There are no documented cases of such triad occurring in the presence of normal serum...

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Bibliographic Details
Published in:Nigerian journal of clinical practice Vol. 18; no. 5; pp. 690 - 692
Main Authors: Rwegerera, G M, Joel, D R, Bakilana, C, Maruza, M P
Format: Journal Article
Language:English
Published: India Medknow Publications and Media Pvt. Ltd 01-09-2015
Subjects:
Adolescent
Anemia, Iron-Deficiency - diagnosis
Anemia, Iron-Deficiency - diet therapy
Care and treatment
Diagnosis
Growth Disorders
Health aspects
Hepatomegaly - diagnosis
Humans
Iron - administration & dosage
Iron deficiency anemia
Male
Malnutrition
Medical examination
Puberty, Delayed
Splenomegaly
Splenomegaly - diagnosis
Syndrome
Treatment Outcome
Zinc - blood
Zinc - deficiency
Nigeria
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Summary:A triad of iron deficiency anemia, hepatosplenomegaly and growth retardation occurring in tandem with zinc deficiency has been reported in the past as components of either Prasad's syndrome or hypopituitarism. There are no documented cases of such triad occurring in the presence of normal serum zinc levels. We report a case of a 14-year-old boy who presented with iron deficiency anemia, hepatosplenomegaly, geophagia and growth retardation with pubertal delay. Investigations ruled out hypopituitarism and coeliac disease. The patient improved dramatically and attained puberty within 15 months of intense nutritional intervention. In conclusion, iron deficiency anemia occurring in the triad without zinc deficiency as seen in this case report has not been reported before; this calls for more research to be able to explain the findings.
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ISSN:1119-3077
DOI:10.4103/1119-3077.151802