Search Results - "Marucci, Luca"

Estrogens and Insulin-Like Growth Factor 1 Modulate Neoplastic Cell Growth in Human Cholangiocarcinoma by Alvaro, Domenico, Barbaro, Barbara, Franchitto, Antonio, Onori, Paolo, Glaser, Shannon S., Alpini, Gianfranco, Francis, Heather, Marucci, Luca, Sterpetti, Paola, Ginanni-Corradini, Stefano, Onetti Muda, Andrea, Dostal, David E., De Santis, Adriano, Attili, Adolfo F., Benedetti, Antonio, Gaudio, Eugenio

“…We investigated the expression of estrogen receptors (ERs), insulin-like growth factor 1 (IGF-1), and IGF-1R (receptor) in human cholangiocarcinoma and…”
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Autocrine/paracrine regulation of the growth of the biliary tree by the neuroendocrine hormone serotonin by Marzioni, Marco, Glaser, Shannon, Francis, Heather, Marucci, Luca, Benedetti, Antonio, Alvaro, Domenico, Taffetani, Silvia, Ueno, Yoshiyuki, Roskams, Tania, Phinizy, Jo Lynne, Venter, Juliet, Fava, Giammarco, LeSage, Gene D., Alpini, Gianfranco

“…Background & Aims : The biliary tree is the target of cholangiopathies that are chronic cholestatic liver diseases characterized by loss of proliferative…”
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cAMP stimulates the secretory and proliferative capacity of the rat intrahepatic biliary epithelium through changes in the PKA/Src/MEK/ERK1/2 pathway by Francis, Heather, Glaser, Shannon, Ueno, Yoshiyuki, LeSage, Gene, Marucci, Luca, Benedetti, Antonio, Taffetani, Silvia, Marzioni, Marco, Alvaro, Domenico, Venter, Julie, Reichenbach, Ramona, Fava, Giammarco, Lynne Phinizy, Jo, Alpini, Gianfranco

“…To evaluate if increased cholangiocyte cAMP levels alone are sufficient to enhance cholangiocyte proliferation and secretion. Normal rats were treated in vivo…”
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Insulin and insulin‐like growth factor‐1 stimulate proliferation and type I collagen accumulation by human hepatic stellate cells: Differential effects on signal transduction pathways by Svegliati‐Baroni, Gianluca, Ridolfi, Francesco, Di Sario, Antonio, Casini, Alessandro, Marucci, Luca, Gaggiotti, Giorgio, Orlandoni, Paolo, Macarri, Giampiero, Perego, Lucia, Benedetti, Antonio, Folli, Franco

“…Insulin and insulin‐like growth factor (IGF‐1) are mitogenic for fibroblasts and smooth muscle cells. IGF‐1 increases in inflamed and fibrotic tissues and…”
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Cholinergic system modulates growth, apoptosis, and secretion of cholangiocytes from bile duct–ligated rats by LeSage, Gene, Alvaro ‡, Domenico, Benedetti §, Antonio, Glaser ∥, Shannon, Marucci §, Luca, Baiocchi ¶, Leonardo, Eisel #, Wendy, Caligiuri, Alessandra, Phinizy ∥, Jo Lynne, Rodgers ¶, Rebecca, Francis ∥, Heather, Alpini ,¶,#, Gianfranco

“…Background & Aims: To investigate the role of the cholinergic system in regulation of cholangiocyte functions, we evaluated the effects of vagotomy on…”
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Endothelin inhibits cholangiocarcinoma growth by a decrease in the vascular endothelial growth factor expression by Fava, Giammarco, DeMorrow, Sharon, Gaudio, Eugenio, Franchitto, Antonio, Onori, Paolo, Carpino, Guido, Glaser, Shannon, Francis, Heather, Coufal, Monique, Marucci, Luca, Alvaro, Domenico, Marzioni, Marco, Horst, Trenton, Mancinelli, Romina, Benedetti, Antonio, Alpini, Gianfranco

“…Background: Endothelins (ET‐1, ET‐2, ET‐3) are peptides with vasoactive properties interacting with ETA and ETB receptors. ET‐1 inhibits secretin‐stimulated…”
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Taurocholate prevents the loss of intrahepatic bile ducts due to vagotomy in bile duct-ligated rats by Marzioni, Marco, LeSage, Gene D, Glaser, Shannon, Patel, Tushar, Marienfeld, Carla, Ueno, Yoshiyuki, Francis, Heather, Alvaro, Domenico, Tadlock, Laura, Benedetti, Antonio, Marucci, Luca, Baiocchi, Leonardo, Phinizy, Jo Lynne, Alpini, Gianfranco

“…The aim of this study was to determine whether taurocholate prevents vagotomy-induced cholangiocyte apoptosis. After bile duct ligation (BDL) + vagotomy, rats…”
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Corticosteroids modulate the secretory processes of the rat intrahepatic biliary epithelium by Alvaro, Domenico, Gigliozzi, Alessandro, Marucci, Luca, Alpini, Gianfranco, Barbaro, Barbara, Monterubbianesi, Rita, Minetola, Lara, Mancino, Maria Grazia, Medina, Juan F., Attili, Adolfo F., Benedetti, Antonio

“…We investigated the expression of glucocorticoid receptors (GcRs) in the intrahepatic biliary epithelium and the role of corticosteroids in the regulation of…”
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Taurocholate feeding prevents CCl4-induced damage of large cholangiocytes through PI3-kinase-dependent mechanism by Marucci, Luca, Alpini, Gianfranco, Glaser, Shannon S, Alvaro, Domenico, Benedetti, Antonio, Francis, Heather, Phinizy, Jo Lynne, Marzioni, Marco, Mauldin, Jeremy, Venter, Julie, Baumann, Brandy, Ugili, Laura, LeSage, Gene

“…Bile acids are cytoprotective in hepatocytes by activating phosphatidylinositol-3-kinase (PI3-K) and its downstream signal AKT. Our aim was to determine…”
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The function of alkaline phosphatase in the liver: Regulation of intrahepatic biliary epithelium secretory activities in the rat by Alvaro, Domenico, Benedetti, Antonio, Marucci, Luca, Delle Monache, Marco, Monterubbianesi, Rita, Di Cosimo, Emanuele, Perego, Lucia, Macarri, Giampiero, Glaser, Shannon, Le Sage, Gene, Alpini, Gianfranco

“…We studied the effects of alkaline phosphatase (AP) on the secretory processes of the rat intrahepatic biliary epithelium as well as the role of the…”
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Chronic ethanol feeding increases apoptosis and cell proliferation in rat liver by Baroni, G S, Marucci, L, Benedetti, A, Mancini, R, Jezequel, A M, Orlandi, F

“…The present study was conducted to evaluate if the increased rate of apoptosis previously reported in the liver of ethanol-treated rats was accompanied by…”
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Leptin enhances cholangiocarcinoma cell growth by Fava, Giammarco, Alpini, Gianfranco, Rychlicki, Chiara, Saccomanno, Stefania, DeMorrow, Sharon, Trozzi, Luciano, Candelaresi, Cinzia, Venter, Julie, Di Sario, Antonio, Marzioni, Marco, Bearzi, Italo, Glaser, Shannon, Alvaro, Domenico, Marucci, Luca, Francis, Heather, Svegliati-Baroni, Gianluca, Benedetti, Antonio

“…Cholangiocarcinoma is a strongly aggressive malignancy with a very poor prognosis. Effective therapeutic strategies are lacking because molecular mechanisms…”
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γ-aminobutyric acid inhibits cholangiocarcinoma growth by cyclic AMP-dependent regulation of the protein kinase A/extracellular signal-regulated kinase 1/2 pathway by FAVA, Giammarco, MARUCCI, Luca, TAFFETANI, Silvia, MARZIONI, Marco, SUMMERS, Ryun, REICHENBACH, Ramona, ALPINI, Gianfranco, GLASER, Shannon, FRANCIS, Heather, DE MORROW, Sharon, BENEDETTI, Antonio, ALVARO, Domenico, VENTER, Julie, MEININGER, Cynthia, PATEL, Tushar

“…We studied the effect of the inhibitory neurotransmitter, gamma-aminobutyric acid (GABA), in the regulation of cholangiocarcinoma growth. We determined the in…”
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Alpha-1 adrenergic receptor agonists modulate ductal secretion of BDL rats via Ca(2+)- and PKC-dependent stimulation of cAMP by LeSage, Gene D, Alvaro, Domenico, Glaser, Shannon, Francis, Heather, Marucci, Luca, Roskams, Tania, Phinizy, Jo Lynne, Marzioni, Marco, Benedetti, Antonio, Taffetani, Silvia, Barbaro, Barbara, Fava, Giammarco, Ueno, Yoshiyuki, Alpini, Gianfranco

“…Acetylcholine potentiates secretin-stimulated ductal secretion by Ca(2+)-calcineurin-mediated modulation of adenylyl cyclase. D2 dopaminergic receptor agonists…”
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Nerve growth factor modulates the proliferative capacity of the intrahepatic biliary epithelium in experimental cholestasis by Gigliozzi, Alessandro, Alpini, Gianfranco, Svegliati Baroni, Gianluca, Marucci, Luca, Drudi Metalli, Veronica, Glaser, Shannon S., Francis, Heather, Grazia Mancino, Maria, Ueno, Yoshiyuki, Barbaro, Barbara, Benedetti, Antonio, Attili, Adolfo F., Alvaro, Domenico

“…Background & Aims: We evaluated the expression of neurotrophins in rat cholangiocytes and the role and mechanisms by which nerve growth factor (NGF) modulates…”
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Adrenergic receptor agonists prevent bile duct injury induced by adrenergic denervation by increased cAMP levels and activation of Akt by Glaser, Shannon, Alvaro, Domenico, Francis, Heather, Ueno, Yoshiyuki, Marucci, Luca, Benedetti, Antonio, De Morrow, Sharon, Marzioni, Marco, Mancino, Maria Grazia, Phinizy, Jo Lynne, Reichenbach, Ramona, Fava, Giammarco, Summers, Ryun, Venter, Julie, Alpini, Gianfranco

“…Loss of parasympathetic innervation after vagotomy impairs cholangiocyte proliferation, which is associated with depressed cAMP levels, impaired ductal…”
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α‐1 adrenergic receptor agonists modulate ductal secretion of BDL rats via Ca2+‐ and PKC‐dependent stimulation of cAMP by LeSage, Gene D., Alvaro, Domenico, Glaser, Shannon, Francis, Heather, Marucci, Luca, Roskams, Tania, Phinizy, Jo Lynne, Marzioni, Marco, Benedetti, Antonio, Taffetani, Silvia, Barbaro, Barbara, Fava, Giammarco, Ueno, Yoshiyuki, Alpini, Gianfranco

“…Acetylcholine potentiates secretin‐stimulated ductal secretion by Ca2+‐calcineurin–mediated modulation of adenylyl cyclase. D2 dopaminergic receptor agonists…”
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Cell proliferation and drug resistance in hepatocellular carcinoma are modulated by Rho GTPase signals by Sterpetti, Paola, Marucci, Luca, Candelaresi, Cinzia, Toksoz, Deniz, Alpini, Gianfranco, Ugili, Laura, Baroni, Gianluca Svegliati, Macarri, Giampiero, Benedetti, Antonio

“…Hepatocellular carcinoma is highly resistant to chemotherapeutic agents, thus the need to discover effective therapeutic molecules to suppress cancer cell…”
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Corticosteroids modulate the secretory processes of the rat intrahepatic biliary epithelium by Alvaro, Domenico, Marucci, Luca, Gigliozzi, Alessandro, Apini, Gianfranco, Papa, Emanuela, Monache, Marco Delle, Monterubbianesi, Rita, Capocaccia, Livio, Benedetti, Antonio

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Gastrin inhibits cholangiocyte growth in bile duct-ligated rats by interaction with cholecystokinin-B/Gastrin receptors via D-myo-inositol 1,4,5-triphosphate-, Ca(2+)-, and protein kinase C alpha-dependent mechanisms by Glaser, S, Benedetti, A, Marucci, L, Alvaro, D, Baiocchi, L, Kanno, N, Caligiuri, A, Phinizy, J L, Chowdury, U, Papa, E, LeSage, G, Alpini, G

“…We studied the role of gastrin in regulating cholangiocyte proliferation induced by bile duct ligation (BDL). In purified cholangiocytes, we evaluated (1) for…”
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