Search Results - "Martorell‐Marugán, Jordi"

Stratification of Systemic Lupus Erythematosus Patients Into Three Groups of Disease Activity Progression According to Longitudinal Gene Expression by Toro‐Domínguez, Daniel, Martorell‐Marugán, Jordi, Goldman, Daniel, Petri, Michelle, Carmona‐Sáez, Pedro, Alarcón‐Riquelme, Marta E.

“…Objective The highly heterogeneous clinical presentation of systemic lupus erythematosus (SLE) is characterized by the unpredictable occurrence of disease…”
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Changes in PRC1 activity during interphase modulate lineage transition in pluripotent cells by Asenjo, Helena G., Alcazar-Fabra, María, Espinosa-Martínez, Mencía, Lopez-Onieva, Lourdes, Gallardo, Amador, Dimitrova, Emilia, Feldmann, Angelika, Pachano, Tomas, Martorell-Marugán, Jordi, Carmona-Sáez, Pedro, Sanchez-Pozo, Antonio, Rada-Iglesias, Álvaro, Klose, Robert J., Landeira, David

“…The potential of pluripotent cells to respond to developmental cues and trigger cell differentiation is enhanced during the G1 phase of the cell cycle, but the…”
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A comprehensive database for integrated analysis of omics data in autoimmune diseases by Martorell-Marugán, Jordi, López-Domínguez, Raúl, García-Moreno, Adrián, Toro-Domínguez, Daniel, Villatoro-García, Juan Antonio, Barturen, Guillermo, Martín-Gómez, Adoración, Troule, Kevin, Gómez-López, Gonzalo, Al-Shahrour, Fátima, González-Rumayor, Víctor, Peña-Chilet, María, Dopazo, Joaquín, Sáez-Rodríguez, Julio, Alarcón-Riquelme, Marta E, Carmona-Sáez, Pedro

“…Autoimmune diseases are heterogeneous pathologies with difficult diagnosis and few therapeutic options. In the last decade, several omics studies have provided…”
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Identification of Exosomal MicroRNA Signature by Liquid Biopsy in Hereditary Hemorrhagic Telangiectasia Patients by Pozo-Agundo, Ana, Villaescusa, Nerea, Martorell-Marugán, Jordi, Soriano, Olga, Leyva, Socorro, Jódar-Reyes, Ana Belén, Botella, Luisa María, Carmona-Sáez, Pedro, Blanco, Francisco Javier

“…Hereditary hemorrhagic telangiectasia (HHT) is a rare autosomal dominant vascular dysplasia characterized by epistaxis, mucocutaneous telangiectases, and…”
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NOMePlot: analysis of DNA methylation and nucleosome occupancy at the single molecule by Requena, Francisco, Asenjo, Helena G., Barturen, Guillermo, Martorell-Marugán, Jordi, Carmona-Sáez, Pedro, Landeira, David

“…Recent technical advances highlight that to understand mammalian development and human disease we need to consider transcriptional and epigenetic cell-to-cell…”
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MiRNA expression as outcome predictor in pediatric AML: systematic evaluation of a new model by Ellson, Ivan, Martorell-Marugán, Jordi, Carmona-Sáez, Pedro, Ramos-Mejia, Verónica

“…Accurately predicting patient outcomes is essential for optimizing treatment and improving outcomes in pediatric acute myeloid leukemia (AML). In recent years,…”
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Detecting Differentially Methylated Promoters in Genes Related to Disease Phenotypes Using R by Martorell-Marugán, Jordi, Carmona-Sáez, Pedro

“…DNA methylation in gene promoters plays a major role in gene expression regulation, and alterations in methylation patterns have been associated with several…”
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Protocol for large scale whole blood immune monitoring by mass cytometry and Cyto Quality Pipeline by Rybakowska, Paulina, Van Gassen, Sofie, Martorell Marugán, Jordi, Quintelier, Katrien, Saeys, Yvan, Alarcón-Riquelme, Marta E., Marañón, Concepción

“…Mass cytometry (MC) is a powerful large-scale immune monitoring technology. To maximize MC data quality, we present a protocol for whole blood analysis…”
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DExMA: An R Package for Performing Gene Expression Meta-Analysis with Missing Genes by Villatoro-García, Juan Antonio, Martorell-Marugán, Jordi, Toro-Domínguez, Daniel, Román-Montoya, Yolanda, Femia, Pedro, Carmona-Sáez, Pedro

“…Meta-analysis techniques allow researchers to jointly analyse different studies to determine common effects. In the field of transcriptomics, these methods…”
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mCSEA: detecting subtle differentially methylated regions by Martorell-Marugán, Jordi, González-Rumayor, Víctor, Carmona-Sáez, Pedro

“…Abstract Motivation The identification of differentially methylated regions (DMRs) among phenotypes is one of the main goals of epigenetic analysis. Although…”
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ImaGEO: integrative gene expression meta-analysis from GEO database by Toro-Domínguez, Daniel, Martorell-Marugán, Jordi, López-Domínguez, Raúl, García-Moreno, Adrián, González-Rumayor, Víctor, Alarcón-Riquelme, Marta E, Carmona-Sáez, Pedro

“…Abstract Summary The Gene Expression Omnibus (GEO) database provides an invaluable resource of publicly available gene expression data that can be integrated…”
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DatAC: A visual analytics platform to explore climate and air quality indicators associated with the COVID-19 pandemic in Spain by Martorell-Marugán, Jordi, Villatoro-García, Juan Antonio, García-Moreno, Adrián, López-Domínguez, Raúl, Requena, Francisco, Merelo, Juan Julián, Lacasaña, Marina, de Dios Luna, Juan, Díaz-Mochón, Juan J., Lorente, Jose A., Carmona-Sáez, Pedro

“…The coronavirus disease 2019 (COVID-19) pandemic has caused an unprecedented global health crisis, with several countries imposing lockdowns to control the…”
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Exploring the interplay between climate, population immunity and SARS-CoV-2 transmission dynamics in Mediterranean countries by Villatoro-García, Juan Antonio, López-Domínguez, Raúl, Martorell-Marugán, Jordi, Luna, Juan de Dios, Lorente, José Antonio, Carmona-Sáez, Pedro

“…The relationship between SARS-CoV-2 transmission and environmental factors has been analyzed in numerous studies since the outbreak of the pandemic, resulting…”
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A survey of gene expression meta-analysis: methods and applications by Toro-Domínguez, Daniel, Villatoro-García, Juan Antonio, Martorell-Marugán, Jordi, Román-Montoya, Yolanda, Alarcón-Riquelme, Marta E, Carmona-Sáez, Pedro

“…Abstract The increasing use of high-throughput gene expression quantification technologies over the last two decades and the fact that most of the published…”
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Placental DNA methylation signatures of maternal smoking during pregnancy and potential impacts on fetal growth by Everson, Todd M., Vives-Usano, Marta, Seyve, Emie, Cardenas, Andres, Lacasaña, Marina, Craig, Jeffrey M., Lesseur, Corina, Baker, Emily R., Fernandez-Jimenez, Nora, Heude, Barbara, Perron, Patrice, Gónzalez-Alzaga, Beatriz, Halliday, Jane, Deyssenroth, Maya A., Karagas, Margaret R., Íñiguez, Carmen, Bouchard, Luigi, Carmona-Sáez, Pedro, Loke, Yuk J., Hao, Ke, Belmonte, Thalia, Charles, Marie A., Martorell-Marugán, Jordi, Muggli, Evelyne, Chen, Jia, Fernández, Mariana F., Tost, Jorg, Gómez-Martín, Antonio, London, Stephanie J., Sunyer, Jordi, Marsit, Carmen J., Lepeule, Johanna, Hivert, Marie-France, Bustamante, Mariona

“…Maternal smoking during pregnancy (MSDP) contributes to poor birth outcomes, in part through disrupted placental functions, which may be reflected in the…”
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EZH2 endorses cell plasticity to non-small cell lung cancer cells facilitating mesenchymal to epithelial transition and tumour colonization by Gallardo, Amador, Molina, Aldara, Asenjo, Helena G., Lopez-Onieva, Lourdes, Martorell-Marugán, Jordi, Espinosa-Martinez, Mencia, Griñan-Lison, Carmen, Alvarez-Perez, Juan Carlos, Cara, Francisca E., Navarro-Marchal, Saul A., Carmona-Sáez, Pedro, Medina, Pedro P., Marchal, Juan Antonio, Granados-Principal, Sergio, Sánchez-Pozo, Antonio, Landeira, David

“…Reversible transition between the epithelial and mesenchymal states are key aspects of carcinoma cell dissemination and the metastatic disease, and thus,…”
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The SWI/SNF complex regulates the expression of miR-222, a tumor suppressor microRNA in lung adenocarcinoma by Peinado, Paola, Andrades, Alvaro, Martorell-Marugán, Jordi, Haswell, Jeffrey R, Slack, Frank J, Carmona-Sáez, Pedro, Medina, Pedro P

“…Abstract SWitch/Sucrose Non-Fermentable (SWI/SNF) chromatin remodeling complexes are key epigenetic regulators that are recurrently mutated in cancer. Most…”
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Scoring personalized molecular portraits identify Systemic Lupus Erythematosus subtypes and predict individualized drug responses, symptomatology and disease progression by Toro-Domínguez, Daniel, Martorell-Marugán, Jordi, Martinez-Bueno, Manuel, López-Domínguez, Raúl, Carnero-Montoro, Elena, Barturen, Guillermo, Goldman, Daniel, Petri, Michelle, Carmona-Sáez, Pedro, Alarcón-Riquelme, Marta E

“…Abstract Objectives Systemic Lupus Erythematosus is a complex autoimmune disease that leads to significant worsening of quality of life and mortality. Flares…”
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DREIMT: a drug repositioning database and prioritization tool for immunomodulation by Troulé, Kevin, López-Fernández, Hugo, García-Martín, Santiago, Reboiro-Jato, Miguel, Carretero-Puche, Carlos, Martorell-Marugán, Jordi, Martín-Serrano, Guillermo, Carmona-Sáez, Pedro, Glez-Peña, Daniel, Al-Shahrour, Fátima, Gómez-López, Gonzalo

“…Abstract Motivation Drug immunomodulation modifies the response of the immune system and can be therapeutically exploited in pathologies such as cancer and…”
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Response to the letter 'testing the effectiveness of MyPROSLE in classifying patients with lupus nephritis' by Toro-Domínguez, Daniel, Martorell-Marugán, Jordi, Martinez-Bueno, Manuel, López-Domínguez, Raúl, Carnero-Montoro, Elena, Barturen, Guillermo, Goldman, Daniel, Petri, Michelle, Carmona-Sáez, Pedro, Alarcón-Riquelme, Marta E

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