Search Results - "Martorana, P. A"

Different lung responses to cigarette smoke in two strains of mice sensitive to oxidants by Bartalesi, B, Cavarra, E, Fineschi, S, Lucattelli, M, Lunghi, B, Martorana, P. A, Lungarella, G

“…The development of cigarette smoke-induced pulmonary changes in C57 Bl/6J and DBA/2 mice was investigated. Both strains are sensitive to oxidants and C57Bl/6J…”
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Collagen phagocytosis by lung alveolar macrophages in animal models of emphysema by Lucattelli, M, Cavarra, E, M. de Santi, M, Tetley, T.D, Martorana, P.A, Lungarella, G

“…Under steady state conditions the intracellular pathway is the major route of collagen catabolism in tissues characterised by rapid collagen turnover. In the…”
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Hoe 694, a new Na+/H+ exchange inhibitor and its effects in cardiac ischaemia by Scholz, W., Albus, U., Lang, H.J., Linz, W., Martorana, P.A., Englert, H.C., Schölkens, B.A.

“…1 The benzoylguanidine derivative Hoe 694 ((3‐methylsulphonyl‐4‐piperidino‐benzoyl) guanidine methanesulphonate) was characterized as an inhibitor of Na+/H+…”
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Cardiovascular actions of the furoxan CAS 1609, a novel nitric oxide donor by Bohn, Helmut, Brendel, Joachim, Martorana, Piero A., Schönafinger, Karl

“…1 This study examines the cardiovascular effects of CAS 1609 (4‐hydroxymethyl‐furoxan‐3‐carboxamide) in vitro as well as in vivo in various animal models. 2…”
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Reduction of myocardial reperfusion injury by an inhibitor of poly (ADP-ribose) synthetase in the pig by Bowes, Joanne, Ruetten, Hartmut, Martorana, Piero A, Stockhausen, Hannelore, Thiemermann, Christoph

“…The effect of the Poly (adenosine 5′-diphosphate ribose) synthetase (PARS) inhibitor 3-aminobenzamide on (i) infarct size caused by regional myocardial…”
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Pallid mice with genetic emphysema. Neutrophil elastase burden and elastin loss occur without alteration in the bronchoalveolar lavage cell population by de Santi, M M, Martorana, P A, Cavarra, E, Lungarella, G

“…According to a current hypothesis, pulmonary emphysema results from damage to the elastic fiber network caused by an imbalance within the lower respiratory…”
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Reduction of infarct size by local angiotensin-converting enzyme inhibition is abolished by a bradykinin antagonist by Martorana, P A, Kettenbach, B, Breipohl, G, Linz, W, Schölkens, B A

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Effects of cigarette smoke in mice with different levels of alpha(1)-proteinase inhibitor and sensitivity to oxidants by Cavarra, E, Bartalesi, B, Lucattelli, M, Fineschi, S, Lunghi, B, Gambelli, F, Ortiz, L A, Martorana, P A, Lungarella, G

“…The role of strain difference in the response to cigarette smoke was investigated in mice. Mice of the strains DBA/2 and C57BL/6J responded to acute cigarette…”
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A scanning electron microscopic investigation of genetic emphysema in tight-skin, pallid, and beige mice, three different C57 BL/6J mutants by Keil, M, Lungarella, G, Cavarra, E, van Even, P, Martorana, P A

“…Three mutants of the C57 BL/6J strain, i.e., the tight-skin (Tsk), pallid (pa), and beige (bg) mice have been reported to develop spontaneous emphysema…”
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Effects of nitric oxide synthase inhibition combined with nitric oxide inhalation in a porcine model of endotoxin shock by Klemm, Peter, Thiemermann, Christoph, Winklmaier, Gisela, Martorana, Piero A., Henning, Rainer

“…1 The present investigation compares the effects of intravenous infusion of the NO synthase inhibitor NG‐monomethyl‐l‐arginine (l‐NMMA) with that of an…”
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Antiischemic effects of pirsidomine, a new nitric oxide donor by Martorana, P A, Kettenbach, B, Bohn, H, Schönafinger, K, Henning, R

“…The antiischemic effect of pirsidomine (CAS 936 (3-(cis-2,6-dimethylpiperidino)-N-(4-methoxybenzoyl))-sydnon imine), a new nitric oxide donor, was investigated…”
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Early Induction of Angiotensin I-Converting Enzyme in Rat Carotid Artery After Balloon Injury by Fernandez-Alfonso, Maria S, Martorana, Piero A, Licka, Ivo, van Even, Paul, Trobisch, Dieter, Scholkens, Bernward A, Paul, Martin

“…Several studies have demonstrated the effectiveness of angiotensin I-converting enzyme (ACE) inhibitors in preventing the neointima formation found after…”
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Lung Injury and Degradation of Extracellular Matrix Components by Aspergillus Fumigatus Serine Proteinase by Ladarola, Paolo, Lungarella, Giuseppe, Martorana, Piero A., Viglio, Simona, Guglielminetti, Maria, Korzus, Edward, Gorrini, Marina, Cavarra, Eleonora, Rossi, Antonio, Travis, Jim, Luisetti, Maurizio

“…Aspergillus fumigatus produces a variety of extracellular proteinases that are believed to be virulence factors towards Aspergillus-related lung disease. Among…”
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The effects of L-arginine on neointimal formation and vascular function following balloon injury in heritable hyperlipidaemic rabbits by GREENLEES, C, WADSWORTH, R. M, MARTORANA, P. A, WAINWRIGHT, C. L

“…The aims of this study were to determine the morphological and functional consequences of balloon angioplasty of the left subclavian artery of Froxfield…”
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Coronary endothelial dysfunction after ischemia and reperfusion in the dog: a functional and morphological investigation by Martorana, P A, Goebel, B, Ruetten, H, Koehl, D, Keil, M

“…Coronary endothelial dysfunction is characterized by a lower response to endothelium-dependent vasodilators such as acetylcholine (ACh) and serotonin (5HT),…”
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Does bradykinin play a role in the cardiac antiischemic effect of the ACE-inhibitors ? by MARTORANA, P. A, LINZ, W, SCHOLKENS, B. A

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Ramiprilat prevents the development of acute coronary endothelial dysfunction in the dog by Martorana, P A, Ruetten, H, Goebel, B, Koehl, D, Roegner, B, Schoelkens, B A, Keil, M

“…We investigated the effect of an infusion of ramiprilat on the development of coronary endothelial dysfunction. In anesthetized dogs, the endothelium-dependent…”
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Cardiovascular effects of the new nitric oxide donor, pirsidomine. Hemodynamic profile and tolerance studies in anesthetized and conscious dogs by Bohn, H, Martorana, P A, Schönafinger, K

“…The hemodynamic profile of pirsidomine, a new donor of NO (nitric oxide), was evaluated in dogs. In anesthetized dogs, the intravenous or intraduodenal…”
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Lung collagen synthesis and deposition in tight-skin mice with genetic emphysema by Gardi, C, Martorana, P A, Calzoni, P, van Even, P, de Santi, M M, Cavarra, E, Lungarella, G

“…The tight-skin (Tsk) mouse is a genetic model of pulmonary emphysema linked to a deficiency of serum antielastase. In this mouse occurrence of connective…”
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Experimental cardiovascular benefits of angiotensin-converting enzyme inhibitors: beyond blood pressure reduction by Schölkens, B A, Linz, W, Martorana, P A

“…In an attempt to separate the cardiac effects of converting-enzyme (CE) inhibition from those on blood pressure, experiments were performed in rats and dogs…”
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