Search Results - "Marton, Melissa"

High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell lines by Yu, Channing, Mannan, Aristotle M, Yvone, Griselda Metta, Ross, Kenneth N, Zhang, Yan-Ling, Marton, Melissa A, Taylor, Bradley R, Crenshaw, Andrew, Gould, Joshua Z, Tamayo, Pablo, Weir, Barbara A, Tsherniak, Aviad, Wong, Bang, Garraway, Levi A, Shamji, Alykhan F, Palmer, Michelle A, Foley, Michael A, Winckler, Wendy, Schreiber, Stuart L, Kung, Andrew L, Golub, Todd R

“…A method called PRISM rapidly identifies drug candidates that are effective against specific cancer cell lines. Hundreds of genetically characterized cell…”
Get full text

Toward performance-diverse small-molecule libraries for cell-based phenotypic screening using multiplexed high-dimensional profiling by Wawer, Mathias J., Li, Kejie, Gustafsdottir, Sigrun M., Ljos, Vebjorn, Bodycombe, Nicole E., Marton, Melissa A., Sokolnicki, Katherine L., Bray, Mark-Anthony, Kemp, Melissa M., Winchester, Ellen, Taylor, Bradley, Grant, George B., Hon, C. Suk-Yee, Duvall, Jeremy R., Wilson, J. Anthony, Bittker, Joshua A., Dančík, Vlado, Narayan, Rajiv, Subramanian, Aravind, Winckler, Wendy, Golub, Todd R., Carpenter, Anne E., Shamji, Alykhan F., Schreiber, Stuart L., Clemons, Paul A.

“…High-throughput screening has become a mainstay of small-molecule probe and early drug discovery. The question of how to build and evolve efficient screening…”
Get full text

Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data by Wainschtein, Pierrick, Jain, Deepti, Zheng, Zhili, Cupples, L. Adrienne, Shadyab, Aladdin H., McKnight, Barbara, Shoemaker, Benjamin M., Mitchell, Braxton D., Psaty, Bruce M., Kooperberg, Charles, Liu, Ching-Ti, Albert, Christine M., Roden, Dan, Chasman, Daniel I., Darbar, Dawood, Lloyd-Jones, Donald M., Arnett, Donna K., Regan, Elizabeth A., Boerwinkle, Eric, Rotter, Jerome I., O’Connell, Jeffrey R., Yanek, Lisa R., de Andrade, Mariza, Allison, Matthew A., McDonald, Merry-Lynn N., Chung, Mina K., Fornage, Myriam, Chami, Nathalie, Smith, Nicholas L., Ellinor, Patrick T., Vasan, Ramachandran S., Mathias, Rasika A., Loos, Ruth J. F., Rich, Stephen S., Lubitz, Steven A., Heckbert, Susan R., Redline, Susan, Guo, Xiuqing, Chen, Y. -D Ida, Laurie, Cecelia A., Hernandez, Ryan D., McGarvey, Stephen T., Goddard, Michael E., Laurie, Cathy C., North, Kari E., Lange, Leslie A., Weir, Bruce S., Yengo, Loic, Yang, Jian, Visscher, Peter M.

“…Analyses of data from genome-wide association studies on unrelated individuals have shown that, for human traits and diseases, approximately one-third to…”
Get full text

Clonal haematopoiesis and risk of chronic liver disease by Wong, Waihay J., Emdin, Connor, Bick, Alexander G., Zekavat, Seyedeh M., Niroula, Abhishek, Pirruccello, James P., Dichtel, Laura, Griffin, Gabriel, Uddin, Md Mesbah, Gibson, Christopher J., Kovalcik, Veronica, Lin, Amy E., McConkey, Marie E., Vromman, Amelie, Sellar, Rob S., Kim, Peter G., Agrawal, Mridul, Weinstock, Joshua, Long, Michelle T., Yu, Bing, Banerjee, Rajarshi, Nicholls, Rowan C., Dennis, Andrea, Kelly, Matt, Loh, Po-Ru, McCarroll, Steve, Boerwinkle, Eric, Vasan, Ramachandran S., Jaiswal, Siddhartha, Johnson, Andrew D., Chung, Raymond T., Corey, Kathleen, Levy, Daniel, Ballantyne, Christie, Ebert, Benjamin L., Natarajan, Pradeep

“…Chronic liver disease is a major public health burden worldwide 1 . Although different aetiologies and mechanisms of liver injury exist, progression of chronic…”
Get full text

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response by Luo, Yang, Kanai, Masahiro, Choi, Wanson, Li, Xinyi, Sakaue, Saori, Yamamoto, Kenichi, Ogawa, Kotaro, Gutierrez-Arcelus, Maria, Gregersen, Peter K., Stuart, Philip E., Elder, James T., Forer, Lukas, Schönherr, Sebastian, Fuchsberger, Christian, Smith, Albert V., Fellay, Jacques, Carrington, Mary, Haas, David W., Guo, Xiuqing, Palmer, Nicholette D., Chen, Yii-Der Ida, Rotter, Jerome I., Taylor, Kent D., Rich, Stephen S., Correa, Adolfo, Wilson, James G., Kathiresan, Sekar, Cho, Michael H., Metspalu, Andres, Esko, Tonu, Okada, Yukinori, Han, Buhm, McLaren, Paul J., Raychaudhuri, Soumya

“…Fine-mapping to plausible causal variation may be more effective in multi-ancestry cohorts, particularly in the MHC, which has population-specific structure…”
Get full text

A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies by Li, Zilin, Li, Xihao, Zhou, Hufeng, Gaynor, Sheila M., Selvaraj, Margaret Sunitha, Arapoglou, Theodore, Quick, Corbin, Liu, Yaowu, Chen, Han, Sun, Ryan, Dey, Rounak, Arnett, Donna K., Auer, Paul L., Bielak, Lawrence F., Bis, Joshua C., Blackwell, Thomas W., Blangero, John, Boerwinkle, Eric, Bowden, Donald W., Brody, Jennifer A., Cade, Brian E., Conomos, Matthew P., Correa, Adolfo, Cupples, L. Adrienne, Curran, Joanne E., de Vries, Paul S., Duggirala, Ravindranath, Franceschini, Nora, Freedman, Barry I., Göring, Harald H. H., Guo, Xiuqing, Kalyani, Rita R., Kooperberg, Charles, Kral, Brian G., Lange, Leslie A., Lin, Bridget M., Manichaikul, Ani, Manning, Alisa K., Martin, Lisa W., Mathias, Rasika A., Meigs, James B., Mitchell, Braxton D., Montasser, May E., Morrison, Alanna C., Naseri, Take, O’Connell, Jeffrey R., Palmer, Nicholette D., Peyser, Patricia A., Psaty, Bruce M., Raffield, Laura M., Redline, Susan, Reiner, Alexander P., Reupena, Muagututi’a Sefuiva, Rice, Kenneth M., Rich, Stephen S., Smith, Jennifer A., Taylor, Kent D., Taub, Margaret A., Vasan, Ramachandran S., Weeks, Daniel E., Wilson, James G., Yanek, Lisa R., Zhao, Wei, Rotter, Jerome I., Willer, Cristen J., Natarajan, Pradeep, Peloso, Gina M., Lin, Xihong

“…Large-scale whole-genome sequencing studies have enabled analysis of noncoding rare-variant (RV) associations with complex human diseases and traits…”
Get full text

Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis by Weinstock, Joshua S., Gopakumar, Jayakrishnan, Burugula, Bala Bharathi, Jahn, Nikolaus, Belk, Julia A., Bouzid, Hind, Daniel, Bence, Miao, Zhuang, Ly, Nghi, Mack, Taralynn M., Luna, Sofia E., Prothro, Katherine P., Mitchell, Shaneice R., Laurie, Cecelia A., Broome, Jai G., Taylor, Kent D., Guo, Xiuqing, Sinner, Moritz F., von Falkenhausen, Aenne S., Shuldiner, Alan R., O’Connell, Jeffrey R., Lewis, Joshua P., Boerwinkle, Eric, Chami, Nathalie, Kenny, Eimear E., Loos, Ruth J. F., Fornage, Myriam, Hou, Lifang, Lloyd-Jones, Donald M., Redline, Susan, Cade, Brian E., Psaty, Bruce M., Bis, Joshua C., Brody, Jennifer A., Yun, Jeong H., Qiao, Dandi, Palmer, Nicholette D., Freedman, Barry I., Bowden, Donald W., Cho, Michael H., Vasan, Ramachandran S., Yanek, Lisa R., Becker, Lewis C., Kardia, Sharon L. R., Peyser, Patricia A., He, Jiang, Rienstra, Michiel, Van der Harst, Pim, Kaplan, Robert, Heckbert, Susan R., Smith, Nicholas L., Wiggins, Kerri L., Arnett, Donna K., Irvin, Marguerite R., Tiwari, Hemant, Cutler, Michael J., Knight, Stacey, Muhlestein, J. Brent, Correa, Adolfo, Raffield, Laura M., Gao, Yan, de Andrade, Mariza, Rotter, Jerome I., Rich, Stephen S., Konkle, Barbara A., Johnsen, Jill M., Wheeler, Marsha M., Smith, J. Gustav, Melander, Olle, Nilsson, Peter M., Custer, Brian S., Duggirala, Ravindranath, Curran, Joanne E., Blangero, John, Xiao, Shujie, Yang, Mao, Gu, C. Charles, Chen, Yii-Der Ida, Lee, Wen-Jane, Marcus, Gregory M., Kane, John P., Pullinger, Clive R., Shoemaker, M. Benjamin, Darbar, Dawood, Roden, Dan M., Kooperberg, Charles, Zhou, Ying, Manson, JoAnn E., Desai, Pinkal, Johnson, Andrew D., Mathias, Rasika A., Abecasis, Goncalo R., Kang, Hyun M., Satpathy, Ansuman T., Natarajan, Pradeep, Kitzman, Jacob O., Whitsel, Eric A., Reiner, Alexander P., Bick, Alexander G., Jaiswal, Siddhartha

“…Mutations in a diverse set of driver genes increase the fitness of haematopoietic stem cells (HSCs), leading to clonal haematopoiesis 1 . These lesions are…”
Get full text

Whole genome sequence analysis of blood lipid levels in >66,000 individuals by Selvaraj, Margaret Sunitha, Li, Xihao, Li, Zilin, Pampana, Akhil, Zhang, David Y., Park, Joseph, Aslibekyan, Stella, Bis, Joshua C., Brody, Jennifer A., Cade, Brian E., Chuang, Lee-Ming, Chung, Ren-Hua, Curran, Joanne E., de las Fuentes, Lisa, de Vries, Paul S., Duggirala, Ravindranath, Freedman, Barry I., Graff, Mariaelisa, Guo, Xiuqing, Heard-Costa, Nancy, Hidalgo, Bertha, Hwu, Chii-Min, Irvin, Marguerite R., Kelly, Tanika N., Kral, Brian G., Lange, Leslie, Li, Xiaohui, Lisa, Martin, Lubitz, Steven A., Manichaikul, Ani W., Michael, Preuss, Montasser, May E., Morrison, Alanna C., Naseri, Take, O’Connell, Jeffrey R., Palmer, Nicholette D., Peyser, Patricia A., Reupena, Muagututia S., Smith, Jennifer A., Sun, Xiao, Taylor, Kent D., Tracy, Russell P., Tsai, Michael Y., Wang, Zhe, Wang, Yuxuan, Bao, Wei, Wilkins, John T., Yanek, Lisa R., Zhao, Wei, Arnett, Donna K., Blangero, John, Boerwinkle, Eric, Bowden, Donald W., Chen, Yii-Der Ida, Correa, Adolfo, Cupples, L. Adrienne, Dutcher, Susan K., Ellinor, Patrick T., Fornage, Myriam, Gabriel, Stacey, Germer, Soren, Gibbs, Richard, He, Jiang, Kaplan, Robert C., Kardia, Sharon L. R., Kim, Ryan, Kooperberg, Charles, Loos, Ruth J. F., Viaud-Martinez, Karine A, Mathias, Rasika A., McGarvey, Stephen T., Mitchell, Braxton D., Nickerson, Deborah, North, Kari E., Psaty, Bruce M., Redline, Susan, Reiner, Alexander P., Vasan, Ramachandran S., Rich, Stephen S., Willer, Cristen, Rotter, Jerome I., Rader, Daniel J., Lin, Xihong, Peloso, Gina M., Natarajan, Pradeep

“…Blood lipids are heritable modifiable causal factors for coronary artery disease. Despite well-described monogenic and polygenic bases of dyslipidemia,…”
Get full text

Powerful, scalable and resource-efficient meta-analysis of rare variant associations in large whole genome sequencing studies by Li, Xihao, Quick, Corbin, Zhou, Hufeng, Gaynor, Sheila M., Liu, Yaowu, Chen, Han, Selvaraj, Margaret Sunitha, Sun, Ryan, Dey, Rounak, Arnett, Donna K., Bielak, Lawrence F., Bis, Joshua C., Blangero, John, Boerwinkle, Eric, Bowden, Donald W., Brody, Jennifer A., Cade, Brian E., Correa, Adolfo, Cupples, L. Adrienne, Curran, Joanne E., de Vries, Paul S., Duggirala, Ravindranath, Freedman, Barry I., Göring, Harald H. H., Guo, Xiuqing, Haessler, Jeffrey, Kalyani, Rita R., Kooperberg, Charles, Kral, Brian G., Lange, Leslie A., Manichaikul, Ani, Martin, Lisa W., McGarvey, Stephen T., Mitchell, Braxton D., Montasser, May E., Morrison, Alanna C., Naseri, Take, O’Connell, Jeffrey R., Palmer, Nicholette D., Peyser, Patricia A., Psaty, Bruce M., Raffield, Laura M., Redline, Susan, Reiner, Alexander P., Reupena, Muagututi’a Sefuiva, Rice, Kenneth M., Rich, Stephen S., Sitlani, Colleen M., Smith, Jennifer A., Taylor, Kent D., Vasan, Ramachandran S., Willer, Cristen J., Wilson, James G., Yanek, Lisa R., Zhao, Wei, Rotter, Jerome I., Natarajan, Pradeep, Peloso, Gina M., Li, Zilin, Lin, Xihong

“…Meta-analysis of whole genome sequencing/whole exome sequencing (WGS/WES) studies provides an attractive solution to the problem of collecting large sample…”
Get full text

Genome sequencing unveils a regulatory landscape of platelet reactivity by Keramati, Ali R., Chen, Ming-Huei, Rodriguez, Benjamin A. T., Yanek, Lisa R., Bhan, Arunoday, Gaynor, Brady J., Ryan, Kathleen, Brody, Jennifer A., Zhong, Xue, Wei, Qiang, Kammers, Kai, Kanchan, Kanika, Iyer, Kruthika, Kowalski, Madeline H., Pitsillides, Achilleas N., Cupples, L. Adrienne, Li, Bingshan, Schlaeger, Thorsten M., Shuldiner, Alan R., O’Connell, Jeffrey R., Ruczinski, Ingo, Mitchell, Braxton D., Faraday, Nauder, Taub, Margaret A., Becker, Lewis C., Lewis, Joshua P., Mathias, Rasika A., Johnson, Andrew D.

“…Platelet aggregation at the site of atherosclerotic vascular injury is the underlying pathophysiology of myocardial infarction and stroke. To build upon prior…”
Get full text

Whole Genome Association Study of the Plasma Metabolome Identifies Metabolites Linked to Cardiometabolic Disease in Black Individuals by Tahir, Usman A., Katz, Daniel H., Avila-Pachecho, Julian, Bick, Alexander G., Pampana, Akhil, Robbins, Jeremy M., Yu, Zhi, Chen, Zsu-Zsu, Benson, Mark D., Cruz, Daniel E., Ngo, Debby, Deng, Shuliang, Shi, Xu, Zheng, Shuning, Eisman, Aaron S., Farrell, Laurie, Hall, Michael E., Correa, Adolfo, Tracy, Russell P., Durda, Peter, Taylor, Kent D., Liu, Yongmei, Johnson, W. Craig, Guo, Xiuqing, Yao, Jie, Chen, Yii-Der Ida, Manichaikul, Ani W., Ruberg, Frederick L., Blaner, William S., Jain, Deepti, Bouchard, Claude, Sarzynski, Mark A., Rich, Stephen S., Rotter, Jerome I., Wang, Thomas J., Wilson, James G., Clish, Clary B., Natarajan, Pradeep, Gerszten, Robert E.

“…Integrating genetic information with metabolomics has provided new insights into genes affecting human metabolism. However, gene-metabolite integration has…”
Get full text

Ultrasensitive plasma-based monitoring of tumor burden using machine-learning-guided signal enrichment by Widman, Adam J., Shah, Minita, Frydendahl, Amanda, Halmos, Daniel, Khamnei, Cole C., Øgaard, Nadia, Rajagopalan, Srinivas, Arora, Anushri, Deshpande, Aditya, Hooper, William F., Quentin, Jean, Bass, Jake, Zhang, Mingxuan, Langanay, Theophile, Andersen, Laura, Steinsnyder, Zoe, Liao, Will, Rasmussen, Mads Heilskov, Henriksen, Tenna Vesterman, Jensen, Sarah Østrup, Nors, Jesper, Therkildsen, Christina, Sotelo, Jesus, Brand, Ryan, Schiffman, Joshua S., Shah, Ronak H., Cheng, Alexandre Pellan, Maher, Colleen, Spain, Lavinia, Krause, Kate, Frederick, Dennie T., den Brok, Wendie, Lohrisch, Caroline, Shenkier, Tamara, Simmons, Christine, Villa, Diego, Mungall, Andrew J., Moore, Richard, Zaikova, Elena, Cerda, Viviana, Kong, Esther, Lai, Daniel, Malbari, Murtaza S., Marton, Melissa, Manaa, Dina, Winterkorn, Lara, Gelmon, Karen, Callahan, Margaret K., Boland, Genevieve, Potenski, Catherine, Wolchok, Jedd D., Saxena, Ashish, Turajlic, Samra, Imielinski, Marcin, Berger, Michael F., Aparicio, Sam, Altorki, Nasser K., Postow, Michael A., Robine, Nicolas, Andersen, Claus Lindbjerg, Landau, Dan A.

“…In solid tumor oncology, circulating tumor DNA (ctDNA) is poised to transform care through accurate assessment of minimal residual disease (MRD) and…”
Get full text

A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels by de Vries, Paul S., Jain, Deepti, Polasek, Ozren, Yanek, Lisa R., Martinez-Perez, Angel, Rudan, Igor, Faraday, Nauder, Rosendaal, Frits R., van Rooij, Frank, Curran, Joanne E., Osburn, William O., O'Connell, Jeffrey R., Doyle, Margaret F., Moissl, Angela P., Deleuze, Jean-François, Almasy, Laura, Alonso, Alvaro, Ament, Seth, Applebaum-Bowden, Deborah, Becker, Diane, Bielak, Larry, Casaburi, Richard, Casella, James, Chavan, Sameer, Comhair, Suzy, Crapo, James, Damcott, Coleen, DeBaun, Michael, Duggirala, Ravi, Ekunwe, Lynette, Ellinor, Patrick, Franceschini, Nora, Frazar, Chris, Gao, Yan, Gass, Margery, Gerszten, Robert, Glahn, David, Gong, Da-Wei, Gross, Colin, Guan, Yue, Hernandez, Ryan, Hidalgo, Bertha, Hoth, Karin, Hsiung, Chao (Agnes), Jain, Deepti, Johnson, Craig, Johnston, Rich, Kelly, Shannon, Khan, Alyna, Kim, Wonji, Kimoff, John, Lin, Henry, Lin, Honghuang, Luo, James, Manning, Alisa, Mathai, Susan, May, Susanne, McGoldrick, Daniel, Mestroni, Luisa, Mignot, Emmanuel, Nickerson, Deborah, Boorgula, Meher Preethi, Preuss, Michael, Psaty, Bruce, Qasba, Pankaj, Qiao, Dandi, Rafaels, Nicholas, Ramachandran, Vasan S., Robillard, Rebecca, Robine, Nicolas, Rotter, Jerome, Saleheen, Danish, Salvi, Sejal, Schwander, Karen, Silverman, Edwin, Skomro, Robert, Snively, Beverly, Sofer, Tamar, Sotoodehnia, Nona, Taylor, Kent D., Tiwari, Hemant, Tsai, Michael, Van Den Berg, David, VandeHaar, Peter, Walts, Avram, Wang, Fei Fei, Wessel, Jennifer, Williams, Kayleen, Winterkorn, Lara, Wu, Joseph, Lindstrom, Sara, Smith, Erin N., MacDonald, James, Braekkan, Sigrid K., Heit, John A., Kooperberg, Charles, März, Winfried, Rotter, Jerome I., Ikram, M. Arfan, Desch, Karl C.

“…•We identified 7 new genetic regions for factor VIII levels, 1 for von Willebrand factor levels, and 3 in a combined analysis.•Silencing B3GNT2 and CD36…”
Get full text

Variant-specific inflation factors for assessing population stratification at the phenotypic variance level by Sofer, Tamar, Zheng, Xiuwen, Laurie, Cecelia A., Gogarten, Stephanie M., Brody, Jennifer A., Conomos, Matthew P., Bis, Joshua C., Thornton, Timothy A., Szpiro, Adam, O’Connell, Jeffrey R., Lange, Ethan M., Gao, Yan, Cupples, L. Adrienne, Psaty, Bruce M., Rice, Kenneth M.

“…In modern Whole Genome Sequencing (WGS) epidemiological studies, participant-level data from multiple studies are often pooled and results are obtained from a…”
Get full text

Abstract 337: Balanced-strand sequencing for highly efficient duplex variant calling in circulating tumor DNA by Widman, Adam, Cheng, Alexandre P., Sossin, Aaron, Rajagopalan, Srinivas, Al Assaad, Majd, Deochand, Sunil, Steinsnyder, Zoe, Manaa, Dina, Marton, Melissa, Reeves, Catherine, Rusinek, Itai, Meiri, Eti, Barad, Omer, Shipony, Zohar, Gilad, Shlomit, Jaimovich, Ariel, Sigouros, Michael, Manohar, Jyothi, King, Abigail, Wilkes, David, Otilano, John, Elemento, Olivier, Faltas, Bishoy M., Mosquera, Juan M., Landau, Dan A.

“…Abstract Several approaches for the detection of circulating tumor DNA (ctDNA) are anchored in the accurate identification of cancer-specific single nucleotide…”
Get full text

Epigenome-wide DNA methylation association study of circulating IgE levels identifies novel targets for asthma by Recto, Kathryn, Huan, Tianxiao, Lee, Gha Young, Bui, Helena, Abecasis, Gonçalo, Aguet, Francois, Albert, Christine, Anugu, Pramod, Arnett, Donna K., Aslibekyan, Stella, Barr, R. Graham, Becker, Diane, Becker, Lewis, Beitelshees, Amber, Benjamin, Emelia, Bis, Joshua, Blackwell, Thomas, Bowden, Donald W., Casas Romero, Juan P., Chang, Yi-Cheng, Chen, Wei-Min, Choi, Seung Hoan, Comhair, Suzy, David, Sean, DeMeo, Dawn, Doddapaneni, Harsha, Duan, Qing, Dugan-Perez, Shannon, El Boueiz, Adel, Flickinger, Matthew, Fornage, Myriam, Fulton, Lucinda, Gabriel, Stacey, Gong, Da-Wei, Haessler, Jeff, He, Jiang, Heckbert, Susan, Hobbs, Brian, Hoth, Karin, Hung, Yi-Jen, Jain, Deepti, Jaquish, Cashell, Johnston, Rich, Kaplan, Robert, Kelly, Shannon, Kenny, Eimear, Kim, Wonji, Kimoff, John, Lange, Christoph, Laurie, Cathy, Laurie, Cecelia, Lee, Wen-Jane, Levine, David, Levy, Daniel, Lewis, Joshua, Li, Xiaohui, Lin, Honghuang, Manichaikul, Ani, Martin, Lisa, Mathias, Rasika, McFarland, Sean, McGoldrick, Daniel, McHugh, Caitlin, Metcalf, Ginger, Min, Nancy, Minster, Ryan L., Montgomery, Courtney, Muzny, Donna, Nelson, Sarah C., Nickerson, Deborah, Okwuonu, Geoffrey, Pack, Allan, Pankow, James, Peyser, Patricia, Preethi Boorgula, Meher, Preuss, Michael, Qasba, Pankaj, Raffield, Laura, Robillard, Rebecca, Roselli, Carolina, Rotter, Jerome, Runnels, Alexi, Sandow, Kevin, Seidman, Jonathan, Smith, Josh, Smith, Nicholas, Sofer, Tamar, Storm, Garrett, Streeten, Elizabeth, Taylor, Matthew, Taylor, Simeon, Vaidya, Dhananjay, Van Den Berg, David, Vrieze, Scott, Walts, Avram, Williams, L. Keoki, Williams, Scott, Wu, Joseph, Zhang, Yingze, Levy, Daniel

“…Identifying novel epigenetic signatures associated with serum immunoglobulin E (IgE) may improve our understanding of molecular mechanisms underlying asthma…”
Get full text

Abstract 5709: Whole genome error-corrected sequencing for sensitive circulating tumor DNA cancer monitoring by Cheng, Alexandre P., Widman, Adam J., Arora, Anushri, Rusinek, Itai, Hooper, William F., Murray, Rebecca, Halmos, Daniel, Langanay, Theophile, Inghirami, Giorgio, Germer, Soren, Marton, Melissa, Helland, Adrienne, Furatero, Rob, McClintock, Jaime, Winterkorn, Lara, Steinsnyder, Zoe, Wang, Yohyoh, Rajagopalan, Srinivas, Alimohamed, Asrar I., Malbari, Murtaza S., Saxena, Ashish, Callahan, Margaret K., Frederick, Dennie T., Spain, Lavinia, Jaimovich, Ariel, Lipson, Doron, Turajlic, Samra, Zody, Michael C., Altorki, Nasser K., Wolchok, Jedd D., Postow, Michael A., Robine, Nicolas, Boland, Genevieve, Landau, Dan A.

“…Abstract In many areas of oncology, we lack sensitive tumor-burden monitoring to guide critical decision making. While circulating tumor DNA (ctDNA) promises…”
Get full text