Search Results - "Martiszus, Briana J"

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    Cinacalcet inhibition of neuronal action potentials preferentially targets the fast inactivated state of voltage-gated sodium channels

    Cinacalcet inhibition of neuronal action potentials preferentially targets the fast inactivated state of voltage-gated sodium channels by Lindner, Jamie S, Rajayer, Salil R, Martiszus, Briana J, Smith, Stephen M

    Published in Frontiers in physiology (19-12-2022)
    “…Voltage-gated sodium channel (VGSC) activation is essential for action potential generation in the brain. Allosteric calcium-sensing receptor (CaSR) agonist,…”
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    Enhanced excitability of cortical neurons in low-divalent solutions is primarily mediated by altered voltage-dependence of voltage-gated sodium channels

    Enhanced excitability of cortical neurons in low-divalent solutions is primarily mediated by altered voltage-dependence of voltage-gated sodium channels by Martiszus, Briana J, Tsintsadze, Timur, Chang, Wenhan, Smith, Stephen M

    Published in eLife (11-05-2021)
    “…Increasing extracellular [Ca2+] ([Ca2+]o) strongly decreases intrinsic excitability in neurons but the mechanism is unclear. By one hypothesis, [Ca2+]o screens…”
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