Search Results - "Martinus, Ryan D."

Role of Mitochondrial Stress Protein HSP60 in Diabetes-Induced Neuroinflammation by Liyanagamage, Donisha Shani Niharika Keembiya, Martinus, Ryan D.

“…Diabetes mellitus is the most common metabolic disorder characterized by hyperglycemia and associated malfunctions of the metabolism of carbohydrates,…”
Get full text

Does Hsp60 Provide a Link between Mitochondrial Stress and Inflammation in Diabetes Mellitus? by Juwono, Joshua, Martinus, Ryan D.

“…The focus of this review is to summarise the known relationships between the expression of heat shock protein 60 (Hsp60) and its association with the…”
Get full text

Hyperglycaemia and oxidative stress upregulate HSP60 & HSP70 expression in HeLa cells by Hall, Luke, Martinus, Ryan D

“…Heat Shock Proteins 60 & 70 (HSP60 & HSP70) are intracellular protein that has been shown to be present at elevated levels in systemic circulation in Type 2…”
Get full text

The effect of complement C5a on mitochondrial functions of PC12 cells by Martinus, Ryan D, Cook, Christian J

“…C5a is thought to play a role during complement-activated neuronal apoptotic cell death in the central nervous system. The mechanisms responsible are however…”
Get full text

Pterocellin A isolated from marine bryozoan Pterocella vesiculosa is cytotoxic to human HeLa cells via mitochondrial apoptotic processes by Wang, Alice T., Prinsep, Michèle R., Martinus, Ryan D.

“…Pterocellin A is a novel bioactive alkaloid isolated from the New Zealand marine bryozoan Pterocella vesiculosa . It exhibits potent antitumour activity…”
Get full text

Comparative proteomics of skeletal muscle mitochondria from myostatin‐null mice by Puddick, Jonathan, Martinus, Ryan D.

“…Myostatin, a secreted protein, is a negative regulator of skeletal muscle growth. Down‐regulating its expression increases skeletal muscle mass that is…”
Get full text

Expression of chaperonin 60 in the hippocampus of the streptozotocin diabetic rat by Yuan, Jiang, Young, Brian J, Martinus, Ryan D

“…Mitochondrial dysfunction and oxidative stress are implicated in the pathological changes observed in the diabetic central nervous system. In this study, using…”
Get full text

Selective Induction of Mitochondrial Chaperones in Response to Loss of the Mitochondrial Genome by Martinus, Ryan D., Garth, Graeme P., Webster, Tracie L., Cartwright, Peter, Naylor, Dean J., Høj, Peter B., Hoogenraad, Nicholas J.

“…Molecular chaperones are known to play key roles in the synthesis, transport and folding of nuclear‐encoded mitochondrial proteins and of proteins encoded by…”
Get full text

Mitochondrial ATP synthase subunit c storage in the ceroid-lipofuscinoses (Batten disease) by Palmer, D N, Fearnley, I M, Walker, J E, Hall, N A, Lake, B D, Wolfe, L S, Haltia, M, Martinus, R D, Jolly, R D

“…The ceroid-lipofuscinoses (Batten disease) are neurodegenerative inherited lysosomal storage diseases of children and animals. A common finding is the…”
Get more information

Upregulation of P-glycoprotein in rat hepatoma ρ° cells: Implications for drug-DNA interactions by Pillay, Vinochani, Martinus, Ryan D., Hill, John S., Phillips, Don R.

“…Rat hepatoma cells lacking mitochondrial DNA (ρ° cells) were used as a model system to examine the possible roles of mitochondrial DNA as a target for the…”
Get full text

Role of chaperones in the biogenesis and maintenance of the mitochondrion by Martinus, R D, Ryan, M T, Naylor, D J, Herd, S M, Hoogenraad, N J, Høj, P B

“…All cells depend on correctly folded proteins for optimal function. A central question in cellular biology is how such folded structures are formed and…”
Get more information

Sheep and other animals with ceroid-lipofuscinoses: their relevance to Batten disease by Jolly, R D, Martinus, R D, Palmer, D N

“…Distinct pathological and histopathological changes distinguish the ceroid-lipofuscinoses from other storage diseases of humans and animals. These various…”
Get more information