Search Results - "Martinuk, Amy"

TRIB1 is a positive regulator of hepatocyte nuclear factor 4-alpha by Soubeyrand, Sébastien, Martinuk, Amy, McPherson, Ruth

“…The TRIB1 locus has been linked to both cardiovascular disease and hepatic steatosis. Recent efforts have revealed TRIB1 to be a major regulator of liver…”
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TRIB1 Is Regulated Post-Transcriptionally by Proteasomal and Non-Proteasomal Pathways by Soubeyrand, Sébastien, Martinuk, Amy, Lau, Paulina, McPherson, Ruth

“…The TRIB1 gene has been associated with multiple malignancies, plasma triglycerides and coronary artery disease (CAD). Despite the clinical significance of…”
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Functional Validation of a Common Nonsynonymous Coding Variant in ZC3HC1 Associated With Protection From Coronary Artery Disease by Linseman, Tara, Soubeyrand, Sébastien, Martinuk, Amy, Nikpay, Majid, Lau, Paulina, McPherson, Ruth

“…BACKGROUND—Although virtually all coronary artery disease associated single-nucleotide polymorphisms identified by genome-wide association studies (GWAS) are…”
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Characterization of a long-acting recombinant human serum albumin-atrial natriuretic factor (ANF) expressed in Pichia pastoris by de Bold, Mercedes Kuroski, Sheffield, William P., Martinuk, Amy, Bhakta, Varsha, Eltringham-Smith, Louise, de Bold, Adolfo J.

“…The cardiac hormone atrial natriuretic factor (ANF) combines pharmacological properties of drugs used to treat essential hypertension (EH), congestive heart…”
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Cardiac hormones ANF and BNP modulate proliferation in the unidirectional mixed lymphocyte reaction by Kuroski de Bold, Mercedes L., PhD, Etchepare, Alejandra, BSc, Martinuk, Amy, MSc, de Bold, Adolfo J., PhD

“…Background Previous investigations have shown that the plasma levels of the cardiac hormone brain natriuretic peptide (BNP) increase during acute cardiac…”
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ERK1/2 regulates hepatocyte Trib1 in response to mitochondrial dysfunction by Soubeyrand, Sébastien, Naing, Thet, Martinuk, Amy, McPherson, Ruth

“…The TRIB1 locus (8q24.13) is a novel locus identified and replicated by several genome-wide association studies for associations with plasma triglycerides,…”
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Functional interaction between COL4A1 / COL4A2 and SMAD3 risk loci for coronary artery disease by Turner, Adam W, Nikpay, Majid, Silva, Anada, Lau, Paulina, Martinuk, Amy, Linseman, Tara A, Soubeyrand, Sebastien, McPherson, Ruth

“…Abstract Objective The COL4A1 / COL4A2 region on chromosome 13q34 is a highly replicated locus for coronary artery disease (CAD). In the normal arterial wall,…”
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Role of Tribbles Pseudokinase 1 (TRIB1) in human hepatocyte metabolism by Soubeyrand, Sébastien, Martinuk, Amy, Naing, Thet, Lau, Paulina, McPherson, Ruth

“…Genome-wide association studies for plasma triglycerides and hepatic steatosis identified a risk locus on chromosome 8q24 close to the TRIB1 gene, encoding…”
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Functional Analysis of a Novel Genome-Wide Association Study Signal in SMAD3 That Confers Protection From Coronary Artery Disease by Turner, Adam W, Martinuk, Amy, Silva, Anada, Lau, Paulina, Nikpay, Majid, Eriksson, Per, Folkersen, Lasse, Perisic, Ljubica, Hedin, Ulf, Soubeyrand, Sebastien, McPherson, Ruth

“…OBJECTIVE—A recent genome-wide association study meta-analysis identified an intronic single nucleotide polymorphism in SMAD3, rs56062135C>T, the minor allele…”
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Functional Analysis of the TRIB1 Associated Locus Linked to Plasma Triglycerides and Coronary Artery Disease by Douvris, Adrianna, Soubeyrand, Sébastien, Naing, Thet, Martinuk, Amy, Nikpay, Majid, Williams, Andrew, Buick, Julie, Yauk, Carole, McPherson, Ruth

“…Background The TRIB1 locus has been linked to hepatic triglyceride metabolism in mice and to plasma triglycerides and coronary artery disease in humans. The…”
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Go protein subunit Goα and the secretory process of the natriuretic peptide hormones ANF and BNP by Roeske, Cassandra, Martinuk, Amy, Choudhry, Asna, Hendy, Geoffrey N, Gollob, Michael, Li, Qiuji, Georgalis, Tina, de Bold, Adolfo J

“…Expression of the G protein subunit Goα has been shown to be prominent in the atria of the rat heart and to be significantly associated with atrial natriuretic…”
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TRIB1 Is Regulated Post-Transcriptionally by Proteasomal and Non-Proteasomal Pathways: e0152346 by Soubeyrand, Sebastien, Martinuk, Amy, Lau, Paulina, McPherson, Ruth

“…The TRIB1 gene has been associated with multiple malignancies, plasma triglycerides and coronary artery disease (CAD). Despite the clinical significance of…”
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Functional Analysis of the TRIB 1 Associated Locus Linked to Plasma Triglycerides and Coronary Artery Disease by Douvris, Adrianna, Soubeyrand, Sébastien, Naing, Thet, Martinuk, Amy, Nikpay, Majid, Williams, Andrew, Buick, Julie, Yauk, Carole, McPherson, Ruth

“…Background The TRIB 1 locus has been linked to hepatic triglyceride metabolism in mice and to plasma triglycerides and coronary artery disease in humans. The…”
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